AU2016251601A1 - Use of (4-hydroxy-2-methyl-1,1-dioxido-2H-benzo(e)(1,2)thiazine-3-yl)(naphthalene-2-yl) methanone in the prevention and/or treatment of non-alcoholic steatohepatitis - Google Patents

Use of (4-hydroxy-2-methyl-1,1-dioxido-2H-benzo(e)(1,2)thiazine-3-yl)(naphthalene-2-yl) methanone in the prevention and/or treatment of non-alcoholic steatohepatitis Download PDF

Info

Publication number
AU2016251601A1
AU2016251601A1 AU2016251601A AU2016251601A AU2016251601A1 AU 2016251601 A1 AU2016251601 A1 AU 2016251601A1 AU 2016251601 A AU2016251601 A AU 2016251601A AU 2016251601 A AU2016251601 A AU 2016251601A AU 2016251601 A1 AU2016251601 A1 AU 2016251601A1
Authority
AU
Australia
Prior art keywords
compound
benzo
methyl
dioxido
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2016251601A
Other languages
English (en)
Inventor
Didier Junquero
Marie Lamothe
Bruno Le Grand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Publication of AU2016251601A1 publication Critical patent/AU2016251601A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
AU2016251601A 2015-04-21 2016-04-20 Use of (4-hydroxy-2-methyl-1,1-dioxido-2H-benzo(e)(1,2)thiazine-3-yl)(naphthalene-2-yl) methanone in the prevention and/or treatment of non-alcoholic steatohepatitis Abandoned AU2016251601A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1553574 2015-04-21
FR1553574A FR3035326B1 (fr) 2015-04-21 2015-04-21 Utilisation de la (4-hydroxy-2-methyl-1,1-dioxido-2h-benzo[e][1,2]thiazin-3-yl)(naphtalen-2-yl)methanone dans la prevention et/ou le traitement de la steatohepatite non-alcoolique
PCT/EP2016/058760 WO2016169983A1 (fr) 2015-04-21 2016-04-20 Utilisation de la (4-hydroxy-2-methyl-1,1-dioxido-2h-benzo[e][1,2]thiazin-3-yl)(naphthalen-2-yl) methanone dans la prevention et/ou le traitement de la steatohepatite non-alcoolique

Publications (1)

Publication Number Publication Date
AU2016251601A1 true AU2016251601A1 (en) 2017-11-30

Family

ID=53484018

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2016251601A Abandoned AU2016251601A1 (en) 2015-04-21 2016-04-20 Use of (4-hydroxy-2-methyl-1,1-dioxido-2H-benzo(e)(1,2)thiazine-3-yl)(naphthalene-2-yl) methanone in the prevention and/or treatment of non-alcoholic steatohepatitis

Country Status (12)

Country Link
US (1) US20180140609A1 (enExample)
EP (1) EP3285774B1 (enExample)
JP (1) JP2018513175A (enExample)
KR (1) KR20170139030A (enExample)
CN (1) CN107530355A (enExample)
AU (1) AU2016251601A1 (enExample)
BR (1) BR112017021586A2 (enExample)
CA (1) CA2981933A1 (enExample)
FR (1) FR3035326B1 (enExample)
MX (1) MX2017013453A (enExample)
RU (1) RU2017137262A (enExample)
WO (1) WO2016169983A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102177304B1 (ko) 2018-07-23 2020-11-10 제이투에이치바이오텍 (주) 비알콜성 지방간염의 예방 또는 치료용 약학 조성물
RU2706026C1 (ru) * 2018-12-28 2019-11-13 Государственное бюджетное учреждение здравоохранения города Москвы Московский клинический научно-практический центр им. А.С. Логинова Департамента здравоохранения города Москвы Способ лечения неалкогольной жировой болезни печени и сахарного диабета второго типа

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0107383D0 (en) * 2001-03-23 2001-05-16 Univ Edinburgh Lipid profile modulation
JP2007197369A (ja) * 2006-01-26 2007-08-09 Sankyo Co Ltd ベンゾチアジン誘導体
FR2942797B1 (fr) * 2009-03-03 2011-04-29 Pf Medicament Derives de benzothiazines, leur preparation et leur application a titre de medicaments
KR101134447B1 (ko) * 2009-11-30 2012-04-10 에스케이 주식회사 아세트아마이드기를 갖는 사이클릭설폰아미드 유도체, 이의 제조방법 및 이를 함유하는 약학 조성물
JP2011213685A (ja) * 2010-04-01 2011-10-27 Kowa Co ベンゾイミダゾリルピペリジン誘導体を有効成分とする１１β−ヒドロキシステロイドデヒドロゲナーゼ１阻害剤
EP2563780B1 (en) * 2010-04-29 2015-05-06 The University Of Edinburgh 3,3-disubstituted-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1h-pyrazol-4-yl)-thiophen-3-yl]-methanones as inhibitors of 11(beta)-hsd1
JP5901025B2 (ja) * 2011-04-19 2016-04-06 第一三共株式会社 テトラヒドロチアゼピン誘導体

Also Published As

Publication number Publication date
WO2016169983A1 (fr) 2016-10-27
RU2017137262A3 (enExample) 2019-09-30
CN107530355A (zh) 2018-01-02
JP2018513175A (ja) 2018-05-24
EP3285774B1 (fr) 2020-01-08
BR112017021586A2 (pt) 2018-07-03
MX2017013453A (es) 2017-12-07
US20180140609A1 (en) 2018-05-24
FR3035326A1 (fr) 2016-10-28
FR3035326B1 (fr) 2017-05-12
EP3285774A1 (fr) 2018-02-28
RU2017137262A (ru) 2019-05-21
CA2981933A1 (fr) 2016-10-27
KR20170139030A (ko) 2017-12-18

Similar Documents

Publication Publication Date Title
DK2605655T3 (en) METHODS OF TREATING SMALL COGNITIVE DISABILITY (MCI) AND RELATED DISORDERS
EP3973965A1 (en) Medical use of pentacyclic triterpenoid saponin compound and pharmaceutical composition thereof
US10870616B2 (en) Derivatives of sobetirome
CN103037692A (zh) 用于抑制肌萎缩的方法
JP2022513449A (ja) 新規な甲状腺模倣物
JP5302900B2 (ja) 脂肪性肝疾患の治療用医薬組成物
US20180140609A1 (en) Use of (4-hydroxy-2-methyl-1,1-dioxido-2h-benzo[e][1,2]thiazine-3-yl)(naphthalene-2-yl) methanone in the prevention and/or treatment of non-alcoholic steatohepatitis
US20200268687A1 (en) Chiral beta-hydroxyethylamines and their use in the treatment of hyperglycemia
TW202135811A (zh) 使用整聯蛋白抑制劑組合治療肝臟疾病
JP4814789B2 (ja) ６−ヒドロキシベンズブロマロン又はその塩からなる医薬組成物
EP2615094A2 (en) Sesterterpene compounds and use thereof
CN116514892B (zh) 甾类化合物、其制备方法和应用
WO2019170157A1 (zh) 一种噻吩[3,2-d]并嘧啶-4-酮类化合物的药物新用途
EP4610250A1 (en) Gpr139 receptor agonist, preparation method therefor, and application thereof
US20230346765A1 (en) Methods of treating xanthine oxidase-related diseases with niflumic acid and derivatives thereof
TWI326215B (en) Use of vasopeptidase inhibitors in the treatment of metabolic diseases, nephropathy and age associated diseases
US11203582B2 (en) Benzamide derivatives for inhibiting endoplasmic reticulum (ER) stress
US20100041716A1 (en) Nitroxides for use in treating or preventing hypercholesterolemia
US20230348364A1 (en) Isotopic thyromimetic compounds
JP2008538413A (ja) Ｍｔｐ阻害化合物をスクリーニングするための方法
HK40011743A (en) Methods of treating alport syndrome using bardoxolone methyl or analogs thereof

Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application