KR20170139030A - 비-알코올성 지방간염의 예방 및/또는 치료에서 (4-하이드록시-2-메틸-1,1-디옥시도-2H-벤조[e][1,2]티아진-3-일)(나프탈렌-2-일)메탄온의 용도 - Google Patents

비-알코올성 지방간염의 예방 및/또는 치료에서 (4-하이드록시-2-메틸-1,1-디옥시도-2H-벤조[e][1,2]티아진-3-일)(나프탈렌-2-일)메탄온의 용도 Download PDF

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Publication number
KR20170139030A
KR20170139030A KR1020177030299A KR20177030299A KR20170139030A KR 20170139030 A KR20170139030 A KR 20170139030A KR 1020177030299 A KR1020177030299 A KR 1020177030299A KR 20177030299 A KR20177030299 A KR 20177030299A KR 20170139030 A KR20170139030 A KR 20170139030A
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KR
South Korea
Prior art keywords
compound
benzo
liver
methyl
thiazin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020177030299A
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English (en)
Korean (ko)
Inventor
마리 라모뜨
디디에르 ?끄로
디디에르 ??끄로
그랑 브뤼노 르
Original Assignee
피에르 파브르 메디카먼트
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Application filed by 피에르 파브르 메디카먼트 filed Critical 피에르 파브르 메디카먼트
Publication of KR20170139030A publication Critical patent/KR20170139030A/ko
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
KR1020177030299A 2015-04-21 2016-04-20 비-알코올성 지방간염의 예방 및/또는 치료에서 (4-하이드록시-2-메틸-1,1-디옥시도-2H-벤조[e][1,2]티아진-3-일)(나프탈렌-2-일)메탄온의 용도 Withdrawn KR20170139030A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1553574 2015-04-21
FR1553574A FR3035326B1 (fr) 2015-04-21 2015-04-21 Utilisation de la (4-hydroxy-2-methyl-1,1-dioxido-2h-benzo[e][1,2]thiazin-3-yl)(naphtalen-2-yl)methanone dans la prevention et/ou le traitement de la steatohepatite non-alcoolique
PCT/EP2016/058760 WO2016169983A1 (fr) 2015-04-21 2016-04-20 Utilisation de la (4-hydroxy-2-methyl-1,1-dioxido-2h-benzo[e][1,2]thiazin-3-yl)(naphthalen-2-yl) methanone dans la prevention et/ou le traitement de la steatohepatite non-alcoolique

Publications (1)

Publication Number Publication Date
KR20170139030A true KR20170139030A (ko) 2017-12-18

Family

ID=53484018

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020177030299A Withdrawn KR20170139030A (ko) 2015-04-21 2016-04-20 비-알코올성 지방간염의 예방 및/또는 치료에서 (4-하이드록시-2-메틸-1,1-디옥시도-2H-벤조[e][1,2]티아진-3-일)(나프탈렌-2-일)메탄온의 용도

Country Status (12)

Country Link
US (1) US20180140609A1 (enExample)
EP (1) EP3285774B1 (enExample)
JP (1) JP2018513175A (enExample)
KR (1) KR20170139030A (enExample)
CN (1) CN107530355A (enExample)
AU (1) AU2016251601A1 (enExample)
BR (1) BR112017021586A2 (enExample)
CA (1) CA2981933A1 (enExample)
FR (1) FR3035326B1 (enExample)
MX (1) MX2017013453A (enExample)
RU (1) RU2017137262A (enExample)
WO (1) WO2016169983A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102177304B1 (ko) 2018-07-23 2020-11-10 제이투에이치바이오텍 (주) 비알콜성 지방간염의 예방 또는 치료용 약학 조성물
RU2706026C1 (ru) * 2018-12-28 2019-11-13 Государственное бюджетное учреждение здравоохранения города Москвы Московский клинический научно-практический центр им. А.С. Логинова Департамента здравоохранения города Москвы Способ лечения неалкогольной жировой болезни печени и сахарного диабета второго типа

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0107383D0 (en) * 2001-03-23 2001-05-16 Univ Edinburgh Lipid profile modulation
JP2007197369A (ja) * 2006-01-26 2007-08-09 Sankyo Co Ltd ベンゾチアジン誘導体
FR2942797B1 (fr) * 2009-03-03 2011-04-29 Pf Medicament Derives de benzothiazines, leur preparation et leur application a titre de medicaments
KR101134447B1 (ko) * 2009-11-30 2012-04-10 에스케이 주식회사 아세트아마이드기를 갖는 사이클릭설폰아미드 유도체, 이의 제조방법 및 이를 함유하는 약학 조성물
JP2011213685A (ja) * 2010-04-01 2011-10-27 Kowa Co ベンゾイミダゾリルピペリジン誘導体を有効成分とする１１β−ヒドロキシステロイドデヒドロゲナーゼ１阻害剤
EP2563780B1 (en) * 2010-04-29 2015-05-06 The University Of Edinburgh 3,3-disubstituted-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1h-pyrazol-4-yl)-thiophen-3-yl]-methanones as inhibitors of 11(beta)-hsd1
JP5901025B2 (ja) * 2011-04-19 2016-04-06 第一三共株式会社 テトラヒドロチアゼピン誘導体

Also Published As

Publication number Publication date
WO2016169983A1 (fr) 2016-10-27
RU2017137262A3 (enExample) 2019-09-30
CN107530355A (zh) 2018-01-02
JP2018513175A (ja) 2018-05-24
EP3285774B1 (fr) 2020-01-08
BR112017021586A2 (pt) 2018-07-03
MX2017013453A (es) 2017-12-07
US20180140609A1 (en) 2018-05-24
FR3035326A1 (fr) 2016-10-28
FR3035326B1 (fr) 2017-05-12
EP3285774A1 (fr) 2018-02-28
RU2017137262A (ru) 2019-05-21
CA2981933A1 (fr) 2016-10-27
AU2016251601A1 (en) 2017-11-30

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PA0105 International application

Patent event date: 20171020

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination