AU2015364640B2 - Polymorphic and amorphous forms of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide - Google Patents

Polymorphic and amorphous forms of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide Download PDF

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AU2015364640B2
AU2015364640B2 AU2015364640A AU2015364640A AU2015364640B2 AU 2015364640 B2 AU2015364640 B2 AU 2015364640B2 AU 2015364640 A AU2015364640 A AU 2015364640A AU 2015364640 A AU2015364640 A AU 2015364640A AU 2015364640 B2 AU2015364640 B2 AU 2015364640B2
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polymorph
hydroxy
methyl
dioxocyclohexa
butanamide
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AU2015364640A1 (en
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Christopher R. Cornell
Peter Giannousis
Mahmoud Mirmehrabi
Paul Mollard
Shazad Suchit
Kieron E. Wesson
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PTC Therapeutics Inc
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PTC Therapeutics Inc
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AU2015364640A 2014-12-16 2015-12-16 Polymorphic and amorphous forms of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide Active AU2015364640B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2020207880A AU2020207880C1 (en) 2014-12-16 2020-07-24 Polymorphic and amorphous forms of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide
AU2022202949A AU2022202949B2 (en) 2014-12-16 2022-05-03 Polymorphic and amorphous forms of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl- 3,6-dioxocyclohexa-1,4-dienyl)butanamide

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Application Number Priority Date Filing Date Title
US201462092743P 2014-12-16 2014-12-16
US62/092,743 2014-12-16
US201562133276P 2015-03-13 2015-03-13
US62/133,276 2015-03-13
PCT/US2015/066211 WO2016100579A1 (en) 2014-12-16 2015-12-16 Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide

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AU2020207880A Division AU2020207880C1 (en) 2014-12-16 2020-07-24 Polymorphic and amorphous forms of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide

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AU2015364640A1 AU2015364640A1 (en) 2017-07-27
AU2015364640B2 true AU2015364640B2 (en) 2020-08-13

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AU2015364640A Active AU2015364640B2 (en) 2014-12-16 2015-12-16 Polymorphic and amorphous forms of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide
AU2020207880A Active AU2020207880C1 (en) 2014-12-16 2020-07-24 Polymorphic and amorphous forms of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide
AU2022202949A Active AU2022202949B2 (en) 2014-12-16 2022-05-03 Polymorphic and amorphous forms of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl- 3,6-dioxocyclohexa-1,4-dienyl)butanamide

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AU2022202949A Active AU2022202949B2 (en) 2014-12-16 2022-05-03 Polymorphic and amorphous forms of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl- 3,6-dioxocyclohexa-1,4-dienyl)butanamide

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US (5) US10251847B2 (https=)
EP (2) EP3233786B1 (https=)
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KR (1) KR102626895B1 (https=)
CN (2) CN107531616B (https=)
AU (3) AU2015364640B2 (https=)
BR (1) BR112017012988B1 (https=)
CA (1) CA2971252C (https=)
DK (1) DK3233786T3 (https=)
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SI (1) SI3233786T1 (https=)
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CA2741767C (en) 2008-10-28 2017-09-12 Ptc Therapeutics, Inc. Process for the production of alpha-tocotrienol and derivatives
JP2014520894A (ja) 2011-07-19 2014-08-25 エジソン ファーマシューティカルズ， インコーポレイテッド 非アルファトコトリエノールの存在下でのアルファトコトリエノールの選択的酸化のための方法
AU2015364640B2 (en) 2014-12-16 2020-08-13 Ptc Therapeutics, Inc. Polymorphic and amorphous forms of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide
EP3390377B1 (en) 2015-12-16 2026-03-25 PTC Therapeutics, Inc. Improved methods for enriching alpha-tocotrienol from mixed tocol compositions
WO2017106803A1 (en) 2015-12-17 2017-06-22 Bioelectron Technology Corporation Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
JP2018083799A (ja) 2016-11-15 2018-05-31 バイオエレクトロン テクノロジー コーポレイション ２−置換アミノ−ナフト［１，２−ｄ］イミダゾール−５−オン化合物またはその製薬学上許容される塩
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