AU2015236106A1 - Non-toxic adjuvant formulation comprising a monophosphoryl lipid a (MPLA)-containing liposome composition and a saponin - Google Patents
Non-toxic adjuvant formulation comprising a monophosphoryl lipid a (MPLA)-containing liposome composition and a saponin Download PDFInfo
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- AU2015236106A1 AU2015236106A1 AU2015236106A AU2015236106A AU2015236106A1 AU 2015236106 A1 AU2015236106 A1 AU 2015236106A1 AU 2015236106 A AU2015236106 A AU 2015236106A AU 2015236106 A AU2015236106 A AU 2015236106A AU 2015236106 A1 AU2015236106 A1 AU 2015236106A1
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- mpla
- adjuvant formulation
- saponin
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Landscapes
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| JP6661454B2 (ja) * | 2016-04-21 | 2020-03-11 | 株式会社東海理化電機製作所 | 表示装置、表示板の製造方法 |
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| PL3615005T3 (pl) * | 2017-04-28 | 2025-10-06 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Kompozycje i sposoby dostarczania szczepionki |
| CN107669692B (zh) * | 2017-09-07 | 2020-09-29 | 中国人民解放军第二军医大学 | Mpla在制备电离辐射致肠道损伤防治药物中的应用 |
| KR102755593B1 (ko) * | 2017-09-08 | 2025-01-20 | 액세스 투 어드밴스드 헬스 인스티튜트 | 사포닌을 포함하는 리포솜 제형 및 사용 방법 |
| WO2020243166A1 (en) * | 2019-05-28 | 2020-12-03 | The Regents Of The University Of California | Th1-polarizing adjuvants for enhancing immunogenicity of hiv antigens |
| CN110613844B (zh) * | 2019-10-23 | 2024-02-27 | 中国医学科学院生物医学工程研究所 | 一种迷你联合佐剂纳米颗粒及其制备方法和应用 |
| US11744874B2 (en) | 2019-12-20 | 2023-09-05 | Nammi Therapeutics, Inc. | Formulated and/or co-formulated liposome compositions containing toll-like receptor (“TLR”) agonist prodrugs useful in the treatment of cancer and methods thereof |
| EP3892296A1 (en) * | 2020-04-07 | 2021-10-13 | InnoMedica Holding AG | Immunogenic composition comprising an antigenic moiety and a liposomal formulation, method of producing the composition, the composition for use as a medicament, in particular for use as a vaccine |
| CN115087435A (zh) * | 2020-06-30 | 2022-09-20 | 艾金株式会社 | 包含阳离子脂质体的用于抑制皂素溶血的组合物 |
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| CN112546233A (zh) * | 2020-12-25 | 2021-03-26 | 常州大学 | 一种负载水不溶性免疫调节分子的透明质酸复合材料及其制备方法 |
| CN114366810B (zh) * | 2022-02-15 | 2024-11-22 | 中国人民解放军陆军军医大学 | 一种可高效诱导体液和细胞免疫的天然微生物和植物来源复合双佐剂及其制备方法和应用 |
| EP4493153A1 (en) * | 2022-03-14 | 2025-01-22 | Pfizer Inc. | Methods for producing an adjuvant |
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| KR20250113501A (ko) | 2022-12-01 | 2025-07-25 | 화이자 인코포레이티드 | 폐렴구균 접합체 백신 제형 |
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| US4302459A (en) | 1980-03-19 | 1981-11-24 | The United States Of America As Represented By The Secretary Of The Army | Liposome carriers in leishmaniasis chemotherapy with 8-aminoquinoline derivatives |
| US5231112A (en) | 1984-04-12 | 1993-07-27 | The Liposome Company, Inc. | Compositions containing tris salt of cholesterol hemisuccinate and antifungal |
| US5916588A (en) | 1984-04-12 | 1999-06-29 | The Liposome Company, Inc. | Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use |
| US4684479A (en) | 1985-08-14 | 1987-08-04 | Arrigo Joseph S D | Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures |
| US6759057B1 (en) | 1986-06-12 | 2004-07-06 | The Liposome Company, Inc. | Methods and compositions using liposome-encapsulated non-steroidal anti-inflammatory drugs |
| CN1093255A (zh) * | 1986-06-17 | 1994-10-12 | 恩特雷麦德有限公司 | 抗甾醇疫苗 |
| IE60901B1 (en) | 1986-08-21 | 1994-08-24 | Vestar Inc | Improved treatment of systemic fungal infections with phospholipid particles encapsulating polyene antifungal antibiotics |
| US6406713B1 (en) | 1987-03-05 | 2002-06-18 | The Liposome Company, Inc. | Methods of preparing low-toxicity drug-lipid complexes |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| AU598958B2 (en) | 1987-11-12 | 1990-07-05 | Vestar, Inc. | Improved amphotericin b liposome preparation |
| US5888519A (en) | 1988-06-02 | 1999-03-30 | The United States Of America As Represented By The Secretary Of The Army | Encapsulated high-concentration lipid a compositions as immunogenic agents to produce human antibodies to prevent or treat gram-negative bacterial infections |
| US5215680A (en) | 1990-07-10 | 1993-06-01 | Cavitation-Control Technology, Inc. | Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles |
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| AU5959494A (en) * | 1992-12-29 | 1994-07-19 | Entremed, Inc | Vaccines against sterols |
| GB9320668D0 (en) * | 1993-10-07 | 1993-11-24 | Secr Defence | Liposomes containing particulare materials |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| US6846489B1 (en) * | 1995-04-25 | 2005-01-25 | Smithkline Beecham Biologicals S.A. | Vaccines containing a saponin and a sterol |
| EP0929293B1 (en) | 1996-08-23 | 2003-10-22 | Sequus Pharmaceuticals, Inc. | Liposomes containing a cisplatin compound |
| US6056973A (en) | 1996-10-11 | 2000-05-02 | Sequus Pharmaceuticals, Inc. | Therapeutic liposome composition and method of preparation |
| EP0932390A1 (en) | 1996-10-11 | 1999-08-04 | Sequus Pharmaceuticals, Inc. | Therapeutic liposome composition and method |
| NZ336538A (en) | 1996-10-15 | 2001-11-30 | Liposome Co Inc | N-acyl phosphatidylethanolamine-mediated liposomal drug delivery |
| US6231859B1 (en) | 1996-12-02 | 2001-05-15 | Aquila Biopharmaceuticals, Inc. | Saponin adjuvant compositions |
| GB9817052D0 (en) * | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| MX2009009213A (es) * | 2007-03-01 | 2010-03-15 | Univ America Catholic | Bacteriofago t4 unido a un substrato. |
| GB0910046D0 (en) * | 2009-06-10 | 2009-07-22 | Glaxosmithkline Biolog Sa | Novel compositions |
| WO2012088414A1 (en) * | 2010-12-23 | 2012-06-28 | Ludwig Institute For Cancer Research Ltd. | Liposomal formulation of nonglycosidic ceramides and uses thereof |
-
2015
- 2015-03-25 CA CA2943190A patent/CA2943190A1/en not_active Abandoned
- 2015-03-25 SG SG11201607396WA patent/SG11201607396WA/en unknown
- 2015-03-25 AU AU2015236106A patent/AU2015236106A1/en not_active Abandoned
- 2015-03-25 MX MX2016012168A patent/MX2016012168A/es unknown
- 2015-03-25 RU RU2016141622A patent/RU2016141622A/ru not_active Application Discontinuation
- 2015-03-25 WO PCT/US2015/022461 patent/WO2015148648A1/en not_active Ceased
- 2015-03-25 KR KR1020167026025A patent/KR102242875B1/ko active Active
- 2015-03-25 JP JP2017502920A patent/JP6608422B2/ja active Active
- 2015-03-25 US US15/127,081 patent/US10434167B2/en active Active
- 2015-03-25 SG SG10201808315UA patent/SG10201808315UA/en unknown
- 2015-03-25 EP EP15716264.5A patent/EP3122380B1/en active Active
- 2015-03-25 CN CN201580026334.9A patent/CN107124869B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10434167B2 (en) | 2019-10-08 |
| SG10201808315UA (en) | 2018-10-30 |
| RU2016141622A3 (enExample) | 2018-10-26 |
| KR20170007242A (ko) | 2017-01-18 |
| KR102242875B1 (ko) | 2021-04-20 |
| RU2016141622A (ru) | 2018-04-25 |
| EP3122380B1 (en) | 2025-03-19 |
| CA2943190A1 (en) | 2015-10-01 |
| CN107124869B (zh) | 2022-04-01 |
| US20170182152A1 (en) | 2017-06-29 |
| WO2015148648A1 (en) | 2015-10-01 |
| CN107124869A (zh) | 2017-09-01 |
| MX2016012168A (es) | 2017-04-25 |
| JP2017515889A (ja) | 2017-06-15 |
| EP3122380A1 (en) | 2017-02-01 |
| JP6608422B2 (ja) | 2019-11-20 |
| SG11201607396WA (en) | 2016-10-28 |
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