AU2015205370B2 - Hydroxy formamide derivatives and their use - Google Patents

Hydroxy formamide derivatives and their use Download PDF

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Publication number
AU2015205370B2
AU2015205370B2 AU2015205370A AU2015205370A AU2015205370B2 AU 2015205370 B2 AU2015205370 B2 AU 2015205370B2 AU 2015205370 A AU2015205370 A AU 2015205370A AU 2015205370 A AU2015205370 A AU 2015205370A AU 2015205370 B2 AU2015205370 B2 AU 2015205370B2
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AU
Australia
Prior art keywords
methyl
furan
hydroxyformamido
heptanamido
carbamoyl
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Ceased
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AU2015205370A
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AU2015205370A1 (en
Inventor
Sarah E. Dowdell
Hilary Schenck Eidam
Mark ELBAN
Ryan Michael Fox
Marlys Hammond
Mark A. Hilfiker
Tram H. Hoang
Lara S. Kallander
Brian Griffin Lawhorn
Sharada Manns
Joanne Philp
David G. Washburn
Guosen Ye
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GlaxoSmithKline Intellectual Property No 2 Ltd
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GlaxoSmithKline Intellectual Property No 2 Ltd
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Publication of AU2015205370A1 publication Critical patent/AU2015205370A1/en
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    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
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  • General Chemical & Material Sciences (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
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  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
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AU2015205370A 2014-01-10 2015-01-09 Hydroxy formamide derivatives and their use Ceased AU2015205370B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461925848P 2014-01-10 2014-01-10
US61/925,848 2014-01-10
PCT/IB2015/050179 WO2015104684A1 (en) 2014-01-10 2015-01-09 Hydroxy formamide derivatives and their use

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AU2015205370A1 AU2015205370A1 (en) 2016-07-21
AU2015205370B2 true AU2015205370B2 (en) 2017-11-30

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US (2) US10450288B2 (enExample)
EP (1) EP3092233A1 (enExample)
JP (2) JP2017507915A (enExample)
KR (1) KR20160106684A (enExample)
CN (2) CN109970797A (enExample)
AU (1) AU2015205370B2 (enExample)
BR (1) BR112016016130A2 (enExample)
CA (1) CA2936467A1 (enExample)
CL (1) CL2016001746A1 (enExample)
CR (1) CR20160316A (enExample)
DO (1) DOP2016000170A (enExample)
EA (1) EA031654B1 (enExample)
IL (1) IL246653A0 (enExample)
MA (1) MA39171A1 (enExample)
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Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
KR20160106684A (ko) * 2014-01-10 2016-09-12 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 히드록시포름아미드 유도체 및 그의 용도
WO2017006295A1 (en) * 2015-07-08 2017-01-12 Glaxosmithkline Intellectual Property (No.2) Limited Hydroxy formamide derivatives and their use
JP2018525353A (ja) 2015-07-09 2018-09-06 グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー２）、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ （Ｎｏ．２） Ｌｉｍｉｔｅｄ Ｂｍｐ１、ｔｌｌ１および／またはｔｌｌ２の阻害剤としての使用するための、ｎ−ヒドロキシホルムアミド化合物およびそれらを含んでなる組成物
CN106699604B (zh) * 2017-01-09 2019-01-01 四川同晟生物医药有限公司 一种沙库比曲及其中间体的制备方法
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