AU2015205370B2 - Hydroxy formamide derivatives and their use - Google Patents

Hydroxy formamide derivatives and their use Download PDF

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Publication number
AU2015205370B2
AU2015205370B2 AU2015205370A AU2015205370A AU2015205370B2 AU 2015205370 B2 AU2015205370 B2 AU 2015205370B2 AU 2015205370 A AU2015205370 A AU 2015205370A AU 2015205370 A AU2015205370 A AU 2015205370A AU 2015205370 B2 AU2015205370 B2 AU 2015205370B2
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AU
Australia
Prior art keywords
methyl
furan
hydroxyformamido
heptanamido
carbamoyl
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Ceased
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AU2015205370A
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AU2015205370A1 (en
Inventor
Sarah E. Dowdell
Hilary Schenck Eidam
Mark ELBAN
Ryan Michael Fox
Marlys Hammond
Mark A. Hilfiker
Tram H. Hoang
Lara S. Kallander
Brian Griffin Lawhorn
Sharada Manns
Joanne Philp
David G. Washburn
Guosen Ye
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GlaxoSmithKline Intellectual Property No 2 Ltd
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GlaxoSmithKline Intellectual Property No 2 Ltd
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Publication of AU2015205370A1 publication Critical patent/AU2015205370A1/en
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    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
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  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
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AU2015205370A 2014-01-10 2015-01-09 Hydroxy formamide derivatives and their use Ceased AU2015205370B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461925848P 2014-01-10 2014-01-10
US61/925,848 2014-01-10
PCT/IB2015/050179 WO2015104684A1 (en) 2014-01-10 2015-01-09 Hydroxy formamide derivatives and their use

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AU2015205370A1 AU2015205370A1 (en) 2016-07-21
AU2015205370B2 true AU2015205370B2 (en) 2017-11-30

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US (2) US10450288B2 (enExample)
EP (1) EP3092233A1 (enExample)
JP (2) JP2017507915A (enExample)
KR (1) KR20160106684A (enExample)
CN (2) CN106103431B (enExample)
AU (1) AU2015205370B2 (enExample)
BR (1) BR112016016130A2 (enExample)
CA (1) CA2936467A1 (enExample)
CL (1) CL2016001746A1 (enExample)
CR (1) CR20160316A (enExample)
DO (1) DOP2016000170A (enExample)
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CN106103431B (zh) * 2014-01-10 2019-03-15 葛兰素史密斯克莱知识产权（第2 号）有限公司 羟基甲酰胺衍生物及其用途
WO2017006295A1 (en) * 2015-07-08 2017-01-12 Glaxosmithkline Intellectual Property (No.2) Limited Hydroxy formamide derivatives and their use
EP3319961A1 (en) 2015-07-09 2018-05-16 Glaxosmithkline Intellectual Property (No. 2) Limited N-hydroxyformamide compounds and compositions comprising them for use as bmp1, tll1 and/or tll2 inhibitors
CN106699604B (zh) * 2017-01-09 2019-01-01 四川同晟生物医药有限公司 一种沙库比曲及其中间体的制备方法
US9862675B1 (en) * 2017-07-05 2018-01-09 King Fahd University Of Petroleum And Minerals Method of N-formylating amines with a phosphonic anhydride
EP3886798B1 (en) 2018-11-29 2026-01-28 Venatorx Pharmaceuticals, Inc. Combination compositions comprising a beta-lactamase inhibitor and uses thereof
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