AU2014306959B2 - Methods for increasing forced expiratory volume in asthmatics using benralizumab - Google Patents

Methods for increasing forced expiratory volume in asthmatics using benralizumab Download PDF

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Publication number
AU2014306959B2
AU2014306959B2 AU2014306959A AU2014306959A AU2014306959B2 AU 2014306959 B2 AU2014306959 B2 AU 2014306959B2 AU 2014306959 A AU2014306959 A AU 2014306959A AU 2014306959 A AU2014306959 A AU 2014306959A AU 2014306959 B2 AU2014306959 B2 AU 2014306959B2
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AU
Australia
Prior art keywords
methods
benralizumab
asthmatics
expiratory volume
forced expiratory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2014306959A
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English (en)
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AU2014306959A1 (en
Inventor
Donald Raible
Lorin Roskos
Bing Wang
Christine Ward
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AstraZeneca AB
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AstraZeneca AB
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Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of AU2014306959A1 publication Critical patent/AU2014306959A1/en
Assigned to ASTRAZENECA AB reassignment ASTRAZENECA AB Request for Assignment Assignors: MEDIMMUNE, LLC
Application granted granted Critical
Publication of AU2014306959B2 publication Critical patent/AU2014306959B2/en
Priority to AU2020201277A priority Critical patent/AU2020201277A1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Endocrinology (AREA)
AU2014306959A 2013-08-12 2014-08-07 Methods for increasing forced expiratory volume in asthmatics using benralizumab Active AU2014306959B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2020201277A AU2020201277A1 (en) 2013-08-12 2020-02-21 Methods for increasing forced expiratory volume in asthmatics using benralizumab

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361864948P 2013-08-12 2013-08-12
US61/864,948 2013-08-12
PCT/US2014/050119 WO2015023507A2 (en) 2013-08-12 2014-08-07 Methods for increasing forced expiratory volume in asthmatics using benralizumab

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2020201277A Division AU2020201277A1 (en) 2013-08-12 2020-02-21 Methods for increasing forced expiratory volume in asthmatics using benralizumab

Publications (2)

Publication Number Publication Date
AU2014306959A1 AU2014306959A1 (en) 2016-02-04
AU2014306959B2 true AU2014306959B2 (en) 2019-11-21

Family

ID=52448838

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2014306959A Active AU2014306959B2 (en) 2013-08-12 2014-08-07 Methods for increasing forced expiratory volume in asthmatics using benralizumab
AU2020201277A Abandoned AU2020201277A1 (en) 2013-08-12 2020-02-21 Methods for increasing forced expiratory volume in asthmatics using benralizumab

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2020201277A Abandoned AU2020201277A1 (en) 2013-08-12 2020-02-21 Methods for increasing forced expiratory volume in asthmatics using benralizumab

Country Status (25)

Country Link
US (1) US9441046B2 (zh)
EP (3) EP3875487A1 (zh)
JP (3) JP6746496B2 (zh)
KR (1) KR102337599B1 (zh)
CN (2) CN105451769A (zh)
AU (2) AU2014306959B2 (zh)
BR (1) BR112016002317A8 (zh)
CA (1) CA2917603C (zh)
CY (2) CY1122033T1 (zh)
DK (2) DK3520811T3 (zh)
ES (2) ES2733602T3 (zh)
HK (2) HK1222559A1 (zh)
HR (2) HRP20190920T1 (zh)
HU (2) HUE043497T2 (zh)
LT (2) LT3520811T (zh)
ME (1) ME03403B (zh)
MX (2) MX2016001384A (zh)
PL (2) PL3033104T3 (zh)
PT (2) PT3520811T (zh)
RS (2) RS58711B1 (zh)
RU (1) RU2703568C2 (zh)
SG (1) SG11201600483QA (zh)
SI (2) SI3033104T1 (zh)
TR (1) TR201907907T4 (zh)
WO (1) WO2015023507A2 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014306956B2 (en) 2013-08-12 2019-11-21 Astrazeneca Ab Methods for reducing exacerbation rates of asthma using benralizumab
KR102337601B1 (ko) * 2013-08-12 2021-12-10 아스트라제네카 아베 벤랄리주맙을 이용하여 천식 증상을 개선시키는 방법
US20150104447A1 (en) * 2013-10-15 2015-04-16 Medimmune, Llc Methods for treating chronic obstructive pulmonary disease using benralizumab
SI3060229T1 (sl) * 2013-10-24 2021-11-30 Astrazeneca Ab Stabilne vodne formulacije protiteles
TW202110479A (zh) * 2019-05-16 2021-03-16 瑞典商阿斯特捷利康公司 使用貝那利珠單抗治療增強型患者群體慢性阻塞性肺病之方法
TW202214692A (zh) * 2020-06-05 2022-04-16 瑞典商阿斯特捷利康公司 治療患有鼻瘜肉的患者的重度氣喘之方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013066780A2 (en) * 2011-11-01 2013-05-10 Medimmune, Llc Methods for reducing the frequency and severity of acute exacerbations of asthma

Family Cites Families (16)

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ES2233974T3 (es) 1995-09-11 2005-06-16 Kyowa Hakko Kogyo Co., Ltd. Anticuerpo contra la cadena alfa del receptor de la interleucina 5 humana.
US6746839B1 (en) * 1998-01-12 2004-06-08 Interleukin Genetics, Inc. Diagnostics and therapeutics for an obstructive airway disease
ES2571230T3 (es) 1999-04-09 2016-05-24 Kyowa Hakko Kirin Co Ltd Procedimiento para controlar la actividad de una molécula inmunofuncional
EP1266663A4 (en) 2000-02-15 2003-07-23 Kyowa Hakko Kogyo Kk EOSINOPHILE SPECIFIC APOPTOSE INDUCTORS
US6946292B2 (en) 2000-10-06 2005-09-20 Kyowa Hakko Kogyo Co., Ltd. Cells producing antibody compositions with increased antibody dependent cytotoxic activity
US8093357B2 (en) 2002-03-01 2012-01-10 Xencor, Inc. Optimized Fc variants and methods for their generation
WO2005035583A1 (ja) 2003-10-08 2005-04-21 Kyowa Hakko Kogyo Co., Ltd. Ｉｌ－５受容体に特異的に結合する抗体組成物
US20060014680A1 (en) 2004-07-13 2006-01-19 Caiding Xu Peptides and compounds that bind to the IL-5 receptor
WO2007041635A2 (en) 2005-10-03 2007-04-12 Xencor, Inc. Fc variants with optimized fc receptor binding properties
JP2010527356A (ja) * 2007-05-14 2010-08-12 メディミューン，エルエルシー 好酸球レベルを低下させる方法
RU2383345C1 (ru) * 2008-08-07 2010-03-10 Государственное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия Росздрава" (ГОУ ВПО "НИЖГМА РОСЗДРАВА") Способ лечения больных бронхиальной астмой
EP3447491A3 (en) * 2010-12-16 2019-06-05 F. Hoffmann-La Roche AG Diagnosis and treatments relating to th2 inhibition
CN102544908B (zh) 2010-12-17 2016-01-06 富士康(昆山)电脑接插件有限公司 电连接器组件及插头连接器
WO2012158954A1 (en) * 2011-05-18 2012-11-22 Medimmune, Llc Methods of diagnosing and treating pulmonary diseases or disorders
AU2014306956B2 (en) * 2013-08-12 2019-11-21 Astrazeneca Ab Methods for reducing exacerbation rates of asthma using benralizumab
KR102337601B1 (ko) * 2013-08-12 2021-12-10 아스트라제네카 아베 벤랄리주맙을 이용하여 천식 증상을 개선시키는 방법

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013066780A2 (en) * 2011-11-01 2013-05-10 Medimmune, Llc Methods for reducing the frequency and severity of acute exacerbations of asthma

Also Published As

Publication number Publication date
MX2021003826A (es) 2021-05-27
CA2917603A1 (en) 2015-02-19
CA2917603C (en) 2023-05-16
SI3033104T1 (sl) 2019-06-28
LT3520811T (lt) 2021-03-25
RS58711B1 (sr) 2019-06-28
SI3520811T1 (sl) 2021-04-30
CY1124399T1 (el) 2022-07-22
CN105451769A (zh) 2016-03-30
EP3033104A4 (en) 2017-03-22
HK1225300A1 (zh) 2017-09-08
EP3033104B1 (en) 2019-04-03
ES2866426T3 (es) 2021-10-19
PT3520811T (pt) 2021-03-15
RS61565B1 (sr) 2021-04-29
JP2020125304A (ja) 2020-08-20
RU2703568C2 (ru) 2019-10-21
AU2014306959A1 (en) 2016-02-04
SG11201600483QA (en) 2016-02-26
JP6746496B2 (ja) 2020-08-26
EP3033104A2 (en) 2016-06-22
HRP20190920T1 (hr) 2019-07-12
BR112016002317A8 (pt) 2018-06-12
TR201907907T4 (tr) 2019-06-21
AU2020201277A1 (en) 2020-03-12
KR20160043049A (ko) 2016-04-20
WO2015023507A8 (en) 2015-09-24
PL3520811T3 (pl) 2021-08-02
EP3520811A1 (en) 2019-08-07
PT3033104T (pt) 2019-06-27
LT3033104T (lt) 2019-06-25
EP3520811B1 (en) 2020-12-30
HK1222559A1 (zh) 2017-07-07
BR112016002317A2 (pt) 2017-12-12
CN111588849A (zh) 2020-08-28
ES2733602T3 (es) 2019-12-02
US20150044203A1 (en) 2015-02-12
DK3520811T3 (da) 2021-03-22
ME03403B (me) 2020-01-20
RU2016108809A3 (zh) 2018-06-18
KR102337599B1 (ko) 2021-12-10
JP2016527325A (ja) 2016-09-08
PL3033104T3 (pl) 2019-09-30
RU2016108809A (ru) 2017-09-18
WO2015023507A3 (en) 2015-04-09
CY1122033T1 (el) 2020-10-14
EP3875487A1 (en) 2021-09-08
US9441046B2 (en) 2016-09-13
JP2022120010A (ja) 2022-08-17
MX2016001384A (es) 2016-08-03
HUE053627T2 (hu) 2021-07-28
WO2015023507A2 (en) 2015-02-19
HRP20210406T1 (hr) 2021-04-30
DK3033104T3 (da) 2019-06-17
HUE043497T2 (hu) 2019-08-28

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Owner name: ASTRAZENECA AB

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