AU2014248562B2 - Oral formulation of polyglucosamine derivatives in combination with a non-fermentable sugar - Google Patents

Oral formulation of polyglucosamine derivatives in combination with a non-fermentable sugar Download PDF

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Publication number
AU2014248562B2
AU2014248562B2 AU2014248562A AU2014248562A AU2014248562B2 AU 2014248562 B2 AU2014248562 B2 AU 2014248562B2 AU 2014248562 A AU2014248562 A AU 2014248562A AU 2014248562 A AU2014248562 A AU 2014248562A AU 2014248562 B2 AU2014248562 B2 AU 2014248562B2
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AU
Australia
Prior art keywords
composition
paag
polyglucosamine
amount
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2014248562A
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English (en)
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AU2014248562A1 (en
Inventor
Shenda Baker
Stacy M. Townsend
William P. Wiesmann
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Synedgen Inc
Original Assignee
Synedgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Publication of AU2014248562A1 publication Critical patent/AU2014248562A1/en
Application granted granted Critical
Publication of AU2014248562B2 publication Critical patent/AU2014248562B2/en
Priority to AU2019202092A priority Critical patent/AU2019202092A1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/736—Chitin; Chitosan; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C17/00—Devices for cleaning, polishing, rinsing or drying teeth, teeth cavities or prostheses; Saliva removers; Dental appliances for receiving spittle
    • A61C17/16—Power-driven cleaning or polishing devices
    • A61C17/20—Power-driven cleaning or polishing devices using ultrasonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4993—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dentistry (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2014248562A 2013-03-12 2014-03-12 Oral formulation of polyglucosamine derivatives in combination with a non-fermentable sugar Active AU2014248562B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2019202092A AU2019202092A1 (en) 2013-03-12 2019-03-26 Oral formulation of polyglucosamine derivatives in combination with a non-fermentable sugar

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361778077P 2013-03-12 2013-03-12
US61/778,077 2013-03-12
PCT/US2014/024864 WO2014165226A2 (en) 2013-03-12 2014-03-12 Oral formulation of polyglucosamine derivatives in combination with a non-fermentable sugar

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2019202092A Division AU2019202092A1 (en) 2013-03-12 2019-03-26 Oral formulation of polyglucosamine derivatives in combination with a non-fermentable sugar

Publications (2)

Publication Number Publication Date
AU2014248562A1 AU2014248562A1 (en) 2015-10-01
AU2014248562B2 true AU2014248562B2 (en) 2019-01-03

Family

ID=51659323

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2014248562A Active AU2014248562B2 (en) 2013-03-12 2014-03-12 Oral formulation of polyglucosamine derivatives in combination with a non-fermentable sugar
AU2019202092A Abandoned AU2019202092A1 (en) 2013-03-12 2019-03-26 Oral formulation of polyglucosamine derivatives in combination with a non-fermentable sugar

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2019202092A Abandoned AU2019202092A1 (en) 2013-03-12 2019-03-26 Oral formulation of polyglucosamine derivatives in combination with a non-fermentable sugar

Country Status (6)

Country Link
US (2) US20160022564A1 (enExample)
EP (1) EP2968080B1 (enExample)
JP (2) JP6842916B2 (enExample)
AU (2) AU2014248562B2 (enExample)
CA (1) CA2905404C (enExample)
WO (1) WO2014165226A2 (enExample)

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US8119780B2 (en) 2006-06-02 2012-02-21 Synedgen, Inc. Chitosan-derivative compounds and methods of controlling microbial populations
GB2463181B (en) 2007-05-14 2013-03-27 Univ New York State Res Found Induction of a physiological dispersion response in bacterial cells in a biofilm
EP3311823B1 (en) 2009-09-02 2020-11-25 Synedgen, Inc. Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds
EP2555760B1 (en) 2010-04-06 2019-10-16 Synedgen, Inc. Chitosan derivatives for the treatment of mucositis or ulceration
CA2883704C (en) 2012-09-20 2021-09-28 Synedgen, Inc. Methods for treatment or prevention of damage resulting from radiation, trauma or shock
WO2014165226A2 (en) 2013-03-12 2014-10-09 Synedgen, Inc. Oral formulation of polyglucosamine derivatives in combination with a non-fermentable sugar
EP3190886B1 (en) 2014-09-11 2024-04-10 Synedgen, Inc. Compositions for use in the treatment of acute respiratory distress syndrome
ITUB20155193A1 (it) * 2015-11-03 2017-05-03 Italfarmaco Spa Sospensioni orali di Givinostat fisicamente e chimicamente stabili
GB201701404D0 (en) 2017-01-27 2017-03-15 Micropharm Ltd Therapies for treating inflammatory disorders
CN107334782A (zh) * 2017-07-26 2017-11-10 吉林省始祖生物波医学研究院有限公司 一种抑菌消炎剂及其制备方法和应用
EP3727336A1 (en) 2017-12-20 2020-10-28 3M Innovative Properties Company Oral compositions and methods of use
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
GB201812261D0 (en) * 2018-07-27 2018-09-12 Micropharm Ltd Therapies for treating oral mucositis
US12083209B2 (en) 2020-02-18 2024-09-10 Sunstar Americas, Inc. Oral care composition

Citations (1)

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Also Published As

Publication number Publication date
JP6842916B2 (ja) 2021-03-17
WO2014165226A3 (en) 2014-12-31
AU2014248562A1 (en) 2015-10-01
JP2016512545A (ja) 2016-04-28
JP2019137702A (ja) 2019-08-22
US10765616B2 (en) 2020-09-08
CA2905404C (en) 2021-07-20
WO2014165226A2 (en) 2014-10-09
US20180289609A1 (en) 2018-10-11
US20160022564A1 (en) 2016-01-28
EP2968080A2 (en) 2016-01-20
AU2019202092A1 (en) 2019-04-18
CA2905404A1 (en) 2014-10-09
EP2968080B1 (en) 2023-05-10
EP2968080A4 (en) 2016-08-31

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