AU2014225373B2 - Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis - Google Patents

Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis Download PDF

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Publication number
AU2014225373B2
AU2014225373B2 AU2014225373A AU2014225373A AU2014225373B2 AU 2014225373 B2 AU2014225373 B2 AU 2014225373B2 AU 2014225373 A AU2014225373 A AU 2014225373A AU 2014225373 A AU2014225373 A AU 2014225373A AU 2014225373 B2 AU2014225373 B2 AU 2014225373B2
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AU
Australia
Prior art keywords
zoledronic acid
osteoarthritis
steroid
halogen
prednisolone
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Active
Application number
AU2014225373A
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English (en)
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AU2014225373A1 (en
Inventor
Ketan Desai
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Levolta Pharmaceuticals Inc
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Levolta Pharmaceuticals Inc
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Application filed by Levolta Pharmaceuticals Inc filed Critical Levolta Pharmaceuticals Inc
Publication of AU2014225373A1 publication Critical patent/AU2014225373A1/en
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Publication of AU2014225373B2 publication Critical patent/AU2014225373B2/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
AU2014225373A 2013-03-08 2014-03-07 Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis Active AU2014225373B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/791,685 US9012432B2 (en) 2013-03-08 2013-03-08 Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis
US13/791,685 2013-03-08
PCT/US2014/022169 WO2014138712A1 (en) 2013-03-08 2014-03-07 Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis

Publications (2)

Publication Number Publication Date
AU2014225373A1 AU2014225373A1 (en) 2015-10-22
AU2014225373B2 true AU2014225373B2 (en) 2018-07-05

Family

ID=51488530

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2014225373A Active AU2014225373B2 (en) 2013-03-08 2014-03-07 Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis

Country Status (12)

Country Link
US (1) US9012432B2 (enExample)
EP (1) EP2964209B1 (enExample)
JP (2) JP6839491B2 (enExample)
KR (1) KR102253394B1 (enExample)
CN (1) CN105324113B (enExample)
AU (1) AU2014225373B2 (enExample)
BR (1) BR112015021503B1 (enExample)
CA (1) CA2941346C (enExample)
EA (1) EA032067B1 (enExample)
ES (1) ES2904365T3 (enExample)
MX (1) MX377447B (enExample)
WO (1) WO2014138712A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017155233A1 (ko) 2016-03-09 2017-09-14 주식회사 바이오펩 염증성 질환의 예방 또는 치료용 펩타이드 및 이의 용도
US10913772B2 (en) 2016-03-09 2021-02-09 Kine Sciences Co., Ltd. Peptide for preventing or treating inflammatory diseases and use thereof
US10913771B2 (en) 2016-03-09 2021-02-09 Kine Sciences Co., Ltd. Peptide for preventing or treating inflammatory diseases and use thereof
WO2017155234A1 (ko) 2016-03-09 2017-09-14 주식회사 바이오펩 염증성 질환의 예방 또는 치료용 펩타이드 및 이의 용도
KR101897122B1 (ko) 2016-03-09 2018-09-10 주식회사 바이오펩 염증성 질환의 예방 또는 치료용 펩타이드 및 이의 용도
JP7127616B2 (ja) 2019-06-04 2022-08-30 横河電機株式会社 情報処理装置、アラーム管理システム、及びアラーム管理方法
WO2021163432A1 (en) * 2020-02-12 2021-08-19 Levolta Pharmaceuticals, Inc. Co-administration of prednisolone/methyl prednisolone and zoledronic acid to treat and prevent osteoarthritis
CN114028571B (zh) * 2021-11-18 2023-04-28 中国医学科学院基础医学研究所 含氮双膦酸盐联合糖皮质激素在预防或治疗病毒性肺炎中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110263537A1 (en) * 2010-04-26 2011-10-27 Ketan Desai Co-administration of steroids and zoledronic acid to prevent and treat side effects from zoledronic acid infusion

Family Cites Families (12)

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EP0275821B1 (de) 1986-11-21 1992-02-26 Ciba-Geigy Ag Neue substituierte Alkandiphosphonsäuren
US7018647B1 (en) * 1999-12-27 2006-03-28 Teikoku Seiyaku Co., Ltd Patches for external use
GB0029111D0 (en) 2000-11-29 2001-01-10 Novartis Ag Organic compounds
CA2449934A1 (en) * 2001-06-08 2002-12-19 Ortho-Mcneil Pharmaceutical, Inc. Treating pain by targeting hyperpolarization-activated, cyclic nucleotide-gated channels
WO2003086415A1 (en) * 2002-04-05 2003-10-23 Merck & Co., Inc. Method for inhibiting bone resorption with an alendronate and vitamin d formulation
MXPA06003063A (es) * 2003-09-19 2006-05-31 Pfizer Prod Inc Composiciones farmaceuticas y metodos que comprenden combinaciones de derivados de 2-alquiliden-19-nor-vitamina- d y un bisfosfonato.
EP1758653A2 (en) * 2004-06-17 2007-03-07 Osteologix A/S Treatments comprising strontium for rheumatic and arthritic diseases and pain
JP5240925B2 (ja) * 2005-05-25 2013-07-17 カロシン ファーマ, インコーポレイテッド 変形性関節症を処置するための方法および組成物
US20070048372A1 (en) * 2005-08-18 2007-03-01 Srz Properties, Inc. Method for treating non-inflammatory osteoarthritic pain
MX2009001248A (es) * 2006-08-03 2009-02-11 Nitec Pharma Ag Tratamiento con glucocorticoide de liberacion prolongada de enfermedad reumatoide.
WO2010071866A2 (en) * 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Combination therapy for arthritis with tranilast
JP5648174B2 (ja) * 2009-05-04 2015-01-07 ヌボ リサーチ インコーポレイテッド 神経腫、神経絞扼、および他の状態と関連する疼痛を処置する方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110263537A1 (en) * 2010-04-26 2011-10-27 Ketan Desai Co-administration of steroids and zoledronic acid to prevent and treat side effects from zoledronic acid infusion

Also Published As

Publication number Publication date
WO2014138712A1 (en) 2014-09-12
MX377447B (es) 2025-03-10
BR112015021503B1 (pt) 2022-09-06
MX2015011671A (es) 2016-05-12
KR102253394B1 (ko) 2021-05-20
ES2904365T3 (es) 2022-04-04
JP2016510765A (ja) 2016-04-11
US20140256681A1 (en) 2014-09-11
CA2941346A1 (en) 2014-09-12
AU2014225373A1 (en) 2015-10-22
EP2964209B1 (en) 2021-10-27
US9012432B2 (en) 2015-04-21
CN105324113A (zh) 2016-02-10
BR112015021503A2 (pt) 2018-05-15
JP6839491B2 (ja) 2021-03-17
EP2964209A1 (en) 2016-01-13
EP2964209A4 (en) 2016-08-03
JP2019104762A (ja) 2019-06-27
CA2941346C (en) 2020-03-10
CN105324113B (zh) 2018-07-03
EA032067B1 (ru) 2019-04-30
KR20150125001A (ko) 2015-11-06
EA201591638A1 (ru) 2016-02-29

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