AU2014222390B2 - Method of preparing 2-((5Z,8Z,11 Z,14Z,17Z)-icosa-5,8,1 1,14,17-pentaenyloxy)butanoic acid - Google Patents

Method of preparing 2-((5Z,8Z,11 Z,14Z,17Z)-icosa-5,8,1 1,14,17-pentaenyloxy)butanoic acid Download PDF

Info

Publication number
AU2014222390B2
AU2014222390B2 AU2014222390A AU2014222390A AU2014222390B2 AU 2014222390 B2 AU2014222390 B2 AU 2014222390B2 AU 2014222390 A AU2014222390 A AU 2014222390A AU 2014222390 A AU2014222390 A AU 2014222390A AU 2014222390 B2 AU2014222390 B2 AU 2014222390B2
Authority
AU
Australia
Prior art keywords
acid
icosa
epa
reaction
butanoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2014222390A
Other languages
English (en)
Other versions
AU2014222390A1 (en
Inventor
Ragnar Hovland
Tore Skjaeret
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pronova Biopharma Norge AS
Original Assignee
Pronova Biopharma Norge AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pronova Biopharma Norge AS filed Critical Pronova Biopharma Norge AS
Publication of AU2014222390A1 publication Critical patent/AU2014222390A1/en
Application granted granted Critical
Publication of AU2014222390B2 publication Critical patent/AU2014222390B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/47—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AU2014222390A 2013-02-28 2014-02-27 Method of preparing 2-((5Z,8Z,11 Z,14Z,17Z)-icosa-5,8,1 1,14,17-pentaenyloxy)butanoic acid Active AU2014222390B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361770601P 2013-02-28 2013-02-28
US61/770,601 2013-02-28
PCT/IB2014/000954 WO2014132135A2 (en) 2013-02-28 2014-02-27 Methods of preparing fatty acid derivatives

Publications (2)

Publication Number Publication Date
AU2014222390A1 AU2014222390A1 (en) 2015-09-17
AU2014222390B2 true AU2014222390B2 (en) 2018-05-31

Family

ID=50972746

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2014222390A Active AU2014222390B2 (en) 2013-02-28 2014-02-27 Method of preparing 2-((5Z,8Z,11 Z,14Z,17Z)-icosa-5,8,1 1,14,17-pentaenyloxy)butanoic acid

Country Status (15)

Country Link
US (1) US9365482B2 (zh)
EP (1) EP2961727B1 (zh)
JP (2) JP6325580B2 (zh)
KR (1) KR102179351B1 (zh)
CN (2) CN107673964B (zh)
AR (1) AR094942A1 (zh)
AU (1) AU2014222390B2 (zh)
DK (1) DK2961727T3 (zh)
ES (1) ES2619714T3 (zh)
HR (1) HRP20170383T1 (zh)
HU (1) HUE031763T2 (zh)
PL (1) PL2961727T3 (zh)
PT (1) PT2961727T (zh)
TW (1) TWI624453B (zh)
WO (1) WO2014132135A2 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019111048A1 (en) 2017-12-06 2019-06-13 Basf As Fatty acid derivatives for treating non-alcoholic steatohepatitis
EP3796901A2 (en) 2018-05-23 2021-03-31 Northsea Therapeutics B.V. Structurally modified fatty acids for improving glycemic control and treating inflammatory bowel disease
MX2023007347A (es) 2020-12-22 2023-08-16 Northsea Therapeutics B V Terapias de combinacion que comprenden acidos grasos estructuralmente mejorados que contienen oxigeno para el tratamiento de la esteatohepatitis no alcoholica.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010128401A1 (en) * 2009-05-08 2010-11-11 Pronova Biopharma Norge As Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0791217B2 (ja) * 1988-11-21 1995-10-04 宇部興産株式会社 光学活性な２−フェノキシブタン酸の製造法
BRPI0718393A2 (pt) * 2006-11-03 2013-11-26 Pronova Biopharma Norge As Álcoois de ácido graxo
WO2009134147A1 (en) * 2008-05-02 2009-11-05 Pronova Biopharma Norge As Lipid compositions containing derivatives of epa and dha an their use thereof
WO2010033466A1 (en) * 2008-09-16 2010-03-25 Phenomix Corporation Macrocyclic inhibitors of hepatitis c protease
EP2248798A1 (en) * 2009-05-08 2010-11-10 Pronova BioPharma Norge AS Novel lipid compounds
JP2014505017A (ja) 2010-11-05 2014-02-27 プロノヴァ・バイオファーマ・ノルゲ・アーエス 脂質化合物を用いる処置方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010128401A1 (en) * 2009-05-08 2010-11-11 Pronova Biopharma Norge As Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas

Also Published As

Publication number Publication date
EP2961727A2 (en) 2016-01-06
KR102179351B1 (ko) 2020-11-18
KR20160002732A (ko) 2016-01-08
CN107673964A (zh) 2018-02-09
DK2961727T3 (en) 2017-03-13
JP2016508523A (ja) 2016-03-22
WO2014132135A2 (en) 2014-09-04
TWI624453B (zh) 2018-05-21
ES2619714T3 (es) 2017-06-26
AR094942A1 (es) 2015-09-09
PL2961727T3 (pl) 2017-06-30
JP6325580B2 (ja) 2018-05-16
HRP20170383T1 (hr) 2017-05-05
US20160009625A1 (en) 2016-01-14
US9365482B2 (en) 2016-06-14
JP2018127479A (ja) 2018-08-16
HUE031763T2 (en) 2017-07-28
PT2961727T (pt) 2017-03-08
EP2961727B1 (en) 2016-12-28
CN105102414B (zh) 2017-08-04
AU2014222390A1 (en) 2015-09-17
TW201500342A (zh) 2015-01-01
CN107673964B (zh) 2021-03-23
WO2014132135A3 (en) 2014-11-27
CN105102414A (zh) 2015-11-25

Similar Documents

Publication Publication Date Title
US11472785B2 (en) Process for purification of tetrahydrocannabinolic- and cannabidiolic acid from plant material extract
Zhu et al. Copper-mediated synthesis of α-trifluoromethylthio-and seleno-α, β-unsaturated carbonyl compounds
JP2020111757A (ja) 高度不飽和脂肪酸アルキルエステル含有組成物の製造方法
AU2014222390B2 (en) Method of preparing 2-((5Z,8Z,11 Z,14Z,17Z)-icosa-5,8,1 1,14,17-pentaenyloxy)butanoic acid
WO2013082265A1 (en) Compositions comprising 20-carbon fatty acids and methods of making and using same
JP6659563B2 (ja) 高純度プロスタグランジンの新規製造方法
US10322996B2 (en) Method for producing N-retinoylcysteic acid alkyl ester
EP2812314A1 (en) Amine salts of prostaglandin analogs
CN103360411B (zh) 依维莫司结晶提纯方法
Taguri et al. Stereospecific inversion of secondary tosylates to yield chiral methyl-branched building blocks, applied to the asymmetric synthesis of leafminer sex pheromones
Piers et al. Stereospecific deconjugation of alkyl (E)-and (Z)-3-trimethylstannyl-2-alkenoates
CN112939826B (zh) 利用大孔吸附树脂从反应液中提取分离硝磺草酮的方法
CN102093272B (zh) 消旋卡多曲化合物及其制法
CN111065641A (zh) 柠檬酸伊沙佐米的制备方法
WO2013008175A1 (fr) Procede de preparation du trans-resveratrol et de ses analogues
JP3401295B2 (ja) ハロゲン化脂肪族カルボニル化合物の製造方法
JPH09316034A (ja) （メタ）アクリル酸低級アルキルエステルの製造における低級アルキルアルコールの回収方法及びそのエステルの製造方法
JP4719830B2 (ja) トランス−カラノライドケトン中間体の製造及びラセミ体カラノライドａを得るカラノライドアルコールのキラル分離
JP2015078128A (ja) 育毛剤

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)