AU2013390806B2 - Polymer chelator conjugates - Google Patents

Polymer chelator conjugates Download PDF

Info

Publication number
AU2013390806B2
AU2013390806B2 AU2013390806A AU2013390806A AU2013390806B2 AU 2013390806 B2 AU2013390806 B2 AU 2013390806B2 AU 2013390806 A AU2013390806 A AU 2013390806A AU 2013390806 A AU2013390806 A AU 2013390806A AU 2013390806 B2 AU2013390806 B2 AU 2013390806B2
Authority
AU
Australia
Prior art keywords
polymer
tissue
chelating
conjugate
collagen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2013390806A
Other languages
English (en)
Other versions
AU2013390806A1 (en
Inventor
Thomas J. Koob
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mimedx Group Inc
Original Assignee
Mimedx Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mimedx Group Inc filed Critical Mimedx Group Inc
Publication of AU2013390806A1 publication Critical patent/AU2013390806A1/en
Application granted granted Critical
Publication of AU2013390806B2 publication Critical patent/AU2013390806B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6435—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a connective tissue peptide, e.g. collagen, fibronectin or gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2013390806A 2013-05-28 2013-10-30 Polymer chelator conjugates Active AU2013390806B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/903,878 2013-05-28
US13/903,878 US9446142B2 (en) 2013-05-28 2013-05-28 Polymer chelator conjugates
PCT/US2013/067620 WO2014193468A1 (en) 2013-05-28 2013-10-30 Polymer chelator conjugates

Publications (2)

Publication Number Publication Date
AU2013390806A1 AU2013390806A1 (en) 2015-12-24
AU2013390806B2 true AU2013390806B2 (en) 2019-02-28

Family

ID=51985370

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013390806A Active AU2013390806B2 (en) 2013-05-28 2013-10-30 Polymer chelator conjugates

Country Status (5)

Country Link
US (1) US9446142B2 (https=)
EP (1) EP3003326A4 (https=)
JP (2) JP6496715B2 (https=)
AU (1) AU2013390806B2 (https=)
WO (1) WO2014193468A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2880157C (en) 2012-08-15 2020-07-21 Mimedx Group, Inc. Reinforced placental tissue grafts and methods of making and using the same
US9943551B2 (en) 2012-08-15 2018-04-17 Mimedx Group, Inc. Tissue grafts composed of micronized placental tissue and methods of making and using the same
US9180145B2 (en) 2012-10-12 2015-11-10 Mimedx Group, Inc. Compositions and methods for recruiting and localizing stem cells
US9155799B2 (en) 2012-11-19 2015-10-13 Mimedx Group, Inc. Cross-linked collagen with at least one bound antimicrobial agent for in vivo release of the agent
US8946163B2 (en) 2012-11-19 2015-02-03 Mimedx Group, Inc. Cross-linked collagen comprising metallic anticancer agents
US10206977B1 (en) 2013-01-18 2019-02-19 Mimedx Group, Inc. Isolated placental stem cell recruiting factors
US9662355B2 (en) 2013-01-18 2017-05-30 Mimedx Group, Inc. Methods for treating cardiac conditions
US10029030B2 (en) 2013-03-15 2018-07-24 Mimedx Group, Inc. Molded placental tissue compositions and methods of making and using the same
US10335433B2 (en) * 2013-04-10 2019-07-02 Mimedx Group, Inc. NDGA polymers and metal complexes thereof
JP6756612B2 (ja) * 2013-08-30 2020-09-16 ミメディクス グループ インコーポレイテッド キレーターを含む微粒子化した胎盤性組成物
WO2015109329A1 (en) 2014-01-17 2015-07-23 Mimedx Group, Inc. Method for inducing angiogenesis
JP7099822B2 (ja) 2014-08-28 2022-07-12 ミメディクス グループ インコーポレイテッド コラーゲンで強化した組織移植片
US12551509B2 (en) 2015-11-18 2026-02-17 Lucina Patent Holdco, Llc Acellular regenerative products and methods of their manufacture

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD289135A5 (de) * 1989-11-16 1991-04-18 Adw Zi F. Molekularbiologie,De Verfahren zur bestimmung reduzierender oder oxidierender stoffe
US20120189571A1 (en) * 2009-02-04 2012-07-26 The Brigham And Women's Hospital., Inc. Nanoscale platinum compounds and methods of use thereof

Family Cites Families (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX163953B (es) 1984-03-27 1992-07-03 Univ New Jersey Med Procedimiento para preparar una matriz biodegradable a base de colageno
USRE35748E (en) 1984-05-29 1998-03-17 Matrix Pharmaceutical, Inc. Treatments employing drug containing matrices for introduction into cellular lesion areas
US4619913A (en) 1984-05-29 1986-10-28 Matrix Pharmaceuticals, Inc. Treatments employing drug-containing matrices for introduction into cellular lesion areas
US4895727A (en) 1985-05-03 1990-01-23 Chemex Pharmaceuticals, Inc. Pharmaceutical vehicles for exhancing penetration and retention in the skin
AU6129486A (en) 1985-07-02 1987-01-30 Target Therapeutics, Inc. Vaso-occlusive collagen composition and method
US4847049A (en) 1985-12-18 1989-07-11 Vitaphore Corporation Method of forming chelated collagen having bactericidal properties
EP0290442A4 (en) 1986-11-19 1990-07-03 Chemex Pharmaceuticals Inc MEDICINAL PREPARATIONS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS.
EP0431164A4 (en) 1989-04-21 1992-06-03 Kishinevsky Selskokhozyaistvenny Institut Imeni M.V. Frunze Preparation with an anti-inflammatory, lactogenous and stimulating action, and method of obtaining it
US5290558A (en) 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
JPH03176064A (ja) 1989-12-05 1991-07-31 Hoechst Japan Ltd 創面被覆材
DE3942954A1 (de) 1989-12-23 1991-06-27 Hoechst Ag Verfahren zur herstellung von aldehyden
US5409690A (en) 1993-06-23 1995-04-25 Chemex Pharmaceuticals, Inc. Treatment of multidrug resistant diseases in cancer cell by potentiating with masoprocol
CA2140053C (en) 1994-02-09 2000-04-04 Joel S. Rosenblatt Collagen-based injectable drug delivery system and its use
US7101857B2 (en) 1996-11-05 2006-09-05 Gp Medical, Inc. Crosslinkable biological material and medical uses
US6013106A (en) 1997-01-22 2000-01-11 St. Jude Medical, Inc. Medical article with adhered antimicrobial metal ions and related methods
US6166184A (en) 1997-08-18 2000-12-26 Medtronic Inc. Process for making a bioprosthetic device
US6030635A (en) 1998-02-27 2000-02-29 Musculoskeletal Transplant Foundation Malleable paste for filling bone defects
US6347241B2 (en) 1999-02-02 2002-02-12 Senorx, Inc. Ultrasonic and x-ray detectable biopsy site marker and apparatus for applying it
US6129757A (en) 1998-05-18 2000-10-10 Scimed Life Systems Implantable members for receiving therapeutically useful compositions
GB2345638A (en) 1998-09-11 2000-07-19 Tissue Science Lab Limited Injectable collagen compositions
ATE424181T1 (de) 1999-06-25 2009-03-15 Procter & Gamble Topische antimikrobielle zusammensetzungen
US6716895B1 (en) 1999-12-15 2004-04-06 C.R. Bard, Inc. Polymer compositions containing colloids of silver salts
US6682760B2 (en) 2000-04-18 2004-01-27 Colbar R&D Ltd. Cross-linked collagen matrices and methods for their preparation
KR100377921B1 (ko) 2000-05-04 2003-03-29 정원태 엑시머레이저 각막절제술에서의 안연고 제조방법
US6565960B2 (en) 2000-06-01 2003-05-20 Shriners Hospital Of Children Polymer composite compositions
EP2272947B1 (en) 2000-09-05 2016-08-10 Biosight Ltd Peptide conjugated anti-cancer prodrugs
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
DK1349918T3 (da) 2000-12-06 2014-11-10 Anthrogenesis Corp Fremgangsmåde til indsamling af stamceller fra moderkagen
US20040028711A1 (en) 2001-02-01 2004-02-12 The Procter & Gamble Company Anhydrous cosmetic compositions
EP3246396B1 (en) 2001-02-14 2020-01-29 Celularity, Inc. Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells
EP2316919B1 (en) 2001-02-14 2015-10-07 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
US6503244B2 (en) 2001-03-07 2003-01-07 Micro Therapeutics, Inc. High pressure injection system
EP1419187A4 (en) * 2001-06-01 2006-06-07 Shriners Hospitals Children COMPOSITIONS BASED ON POLYMER COMPOSITES
EP1273308A1 (en) * 2001-07-03 2003-01-08 Fuji Photo Film B.V. Peptide-flavonoid conjugates, their preparation and use in uv protection
WO2003032735A1 (en) 2001-10-18 2003-04-24 Lifecell Corporation Remodeling of tissues and organs
US20030187515A1 (en) 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
AU2003250666A1 (en) 2002-07-29 2004-02-16 Asahi Kasei Kabushiki Kaisha Stem cells for treating pancreatic damage
WO2004055156A2 (en) 2002-12-17 2004-07-01 Technion Research And Development Foundation Ltd. A vegf variant that lacks vegfr-1 binding activity and its use in promotion of re-endothelization and prevention of in-stent restenosis
WO2005032572A2 (en) 2003-10-03 2005-04-14 Vib Vzw Means and methods for the recruitment and identification of stem cells
US20050142161A1 (en) 2003-12-30 2005-06-30 Freeman Lynetta J. Collagen matrix for soft tissue augmentation
WO2005079741A1 (en) 2004-02-13 2005-09-01 Cognis France S.A.S. Cosmetic composition comprising an extract of the leaves of castanea sativa
JP4963670B2 (ja) * 2004-04-07 2012-06-27 レスベラトロル パートナーズ， エルエルシー 栄養補助サプリメントおよびそれを処理する方法
US7794490B2 (en) 2004-06-22 2010-09-14 Boston Scientific Scimed, Inc. Implantable medical devices with antimicrobial and biodegradable matrices
BRPI0611739A2 (pt) * 2005-06-10 2011-12-20 Celgene Corp colágeno de atelopeptìdeo, composição, método e kit para aumentar, avolumar ou substituir tecido de um mamìfero, e, processos para preparar e para reticular colágeno de atelopeptìdeo, e para reduzir a quantidade de partìculas virais em uma composição de colágeno
JP4941845B2 (ja) * 2005-08-24 2012-05-30 イーティーエイチ・チューリッヒ 表面改質のために有用なカテコール等価分子の製造方法
CA2999420A1 (en) 2005-09-27 2007-04-05 Tissuetech, Inc. Amniotic membrane preparations and purified compositions and methods of use
CA2626460A1 (en) 2005-10-18 2007-04-26 Organogenesis, Inc. Antimicrobial collagenous constructs
EP1948259B1 (en) 2005-10-26 2017-03-22 Genesis Technologies Limited Acellular bioabsorbable tissue regeneration matrices produced by incubating acellular blood products
WO2007083984A1 (en) 2006-01-23 2007-07-26 Gwangju Institute Of Science And Technology Conjugate comprising pharmaceutical active compound covalently bound to mucoadhesive polymer and transmucosal delivery method of pharmaceutical active compound using the same
EP1998742A2 (en) 2006-03-08 2008-12-10 Nuviance, INC. Transdermal drug delivery compositions and topical compositions for application on the skin
US20070248575A1 (en) 2006-04-19 2007-10-25 Jerome Connor Bone graft composition
US8454934B2 (en) * 2006-05-25 2013-06-04 Canadian Blood Services High molecular weight chelation structure
CN101501185A (zh) * 2006-06-09 2009-08-05 人类起源公司 胎盘巢(placental niche)及其培养干细胞的用途
US20080020012A1 (en) 2006-06-22 2008-01-24 Ju Young M Collagen scaffolds, medical implants with same and methods of use
TW200817019A (en) 2006-07-10 2008-04-16 Univ Columbia De novo formation and regeneration of vascularized tissue from tissue progenitor cells and vascular progenitor cells
US8372437B2 (en) 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
US20080050347A1 (en) 2006-08-23 2008-02-28 Ichim Thomas E Stem cell therapy for cardiac valvular dysfunction
KR20230146124A (ko) * 2006-10-06 2023-10-18 셀룰래리티 인코포레이티드 천연(텔로펩티드) 태반 콜라겐 조성물
WO2008048663A2 (en) 2006-10-18 2008-04-24 Bacterin International, Inc. Novel process for devitalized/acellular tissue for transplantation
AU2007339257B2 (en) 2006-12-27 2013-01-10 Shriners Hospitals For Children Woven and/or braided fiber implants and methods of making same
CA2678821C (en) 2007-02-20 2015-12-01 Shriners Hospitals For Children In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers
US20080233552A1 (en) 2007-03-22 2008-09-25 David Hui-Kang Ma Method of cross-linking amnion to be an improved biomedical material
AU2008240191B2 (en) 2007-04-12 2013-09-19 Zimmer, Inc. Compositions and methods for tissue repair
US20090036996A1 (en) 2007-08-03 2009-02-05 Roeber Peter J Knit PTFE Articles and Mesh
EP4559488A3 (en) 2007-09-07 2025-08-13 MiMedx Group, Inc. Placental tissue grafts and improved methods of preparing and using the same
US20100317677A1 (en) 2007-09-11 2010-12-16 Hassel Bret A Methods of Treating a Microbial Infection by Modulating RNase-L Expression and/or Activity
WO2009048780A1 (en) 2007-10-08 2009-04-16 The University Of Kentucky Research Foundation Polymer-metal chelator conjugates and uses thereof
US8440199B2 (en) 2007-12-12 2013-05-14 Imperial Innovations Limited Methods for mobilizing mesenchymal stem cells in a patient
US9681869B2 (en) 2008-02-22 2017-06-20 Mimedx Group, Inc. Biostaples suitable for wrist, hand and other ligament replacements or repairs
WO2009137829A2 (en) 2008-05-09 2009-11-12 Wake Forest University Health Sciences Directed stem cell recruitment
US9216077B2 (en) 2008-05-16 2015-12-22 Mimedx Group, Inc. Medical constructs of twisted lengths of collagen fibers and methods of making same
WO2010042205A2 (en) 2008-10-09 2010-04-15 Mimedx, Inc. Methods of making biocomposite medical constructs and related constructs including artificial tissues, vessels and patches
NZ592839A (en) 2008-11-21 2012-10-26 Anthrogenesis Corp Treatment of diseases, disorders or conditions of the lung using placental cells
CN101433556A (zh) 2008-12-05 2009-05-20 成都青山利康药业有限公司 含胎盘成分的保健品组合物及制备方法
US20100291182A1 (en) 2009-01-21 2010-11-18 Arsenal Medical, Inc. Drug-Loaded Fibers
KR101132625B1 (ko) 2010-02-03 2012-04-02 주식회사 바이오랜드 콘택트 렌즈 형태의 양막 드레싱의 제조 방법
CA2790436A1 (en) 2010-02-18 2011-08-25 Osiris Therapeutics, Inc. Immunocompatible chorionic membrane products
US9005285B2 (en) 2010-05-17 2015-04-14 Mimedx Group, Inc. Compressible tubes for placing implants and related medical kits and methods of using same
US8840665B2 (en) 2010-06-11 2014-09-23 Liventa Bioscience, Inc. Method of tendon repair with amnion and chorion constructs
US20120010708A1 (en) 2010-07-08 2012-01-12 AFcell Medical Amnion and chorion replacement cover and uses thereof in surgical repair of muscles
EP2640738A1 (en) 2010-11-15 2013-09-25 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research Anti-fungal agents
EP2458043A1 (en) 2010-11-24 2012-05-30 SpinPlant GmbH Product of crosslinked material and method for producing the same
US20120189586A1 (en) 2011-01-21 2012-07-26 Carl Randall Harrell Human Placental Derived Extracellular Matrix and Uses Therof
KR102118457B1 (ko) 2011-02-14 2020-06-03 미메딕스 그룹 인크. 가교제로 변형된 조직 이식편 및 그것의 제조 및 사용 방법
US9636209B2 (en) * 2011-03-08 2017-05-02 Mimedx Group, Inc. Collagen fiber ribbons with integrated fixation sutures and methods of making the same
US9327029B2 (en) 2011-05-05 2016-05-03 Celacare Technologies, Llc Antimicrobial silver hydrogel composition for the treatment of burns and wounds
US9186382B2 (en) 2011-12-02 2015-11-17 Mimedx Group, Inc. Placental tissue grafts produced by chemical dehydration/freeze-drying and methods for making and using the same
CA2857636C (en) 2011-12-22 2020-06-23 Mimedx Group Inc. Cross-linked dehydrated placental tissue grafts and methods for making and using the same
EP2897625B1 (en) * 2012-09-10 2019-10-23 Wake Forest University Health Sciences Amniotic membrane and its use in wound healing and tissue engineering constructs

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD289135A5 (de) * 1989-11-16 1991-04-18 Adw Zi F. Molekularbiologie,De Verfahren zur bestimmung reduzierender oder oxidierender stoffe
US20120189571A1 (en) * 2009-02-04 2012-07-26 The Brigham And Women's Hospital., Inc. Nanoscale platinum compounds and methods of use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Cai, W et al (2004) Journal of the American Chemical Society 126: 15030-15031 *
MA, HW et al (2006) Journal of Membrane Science 278: 373-380 *

Also Published As

Publication number Publication date
JP2019006802A (ja) 2019-01-17
WO2014193468A1 (en) 2014-12-04
EP3003326A4 (en) 2017-04-26
JP6496715B2 (ja) 2019-04-03
JP2016530217A (ja) 2016-09-29
US20140356451A1 (en) 2014-12-04
EP3003326A1 (en) 2016-04-13
AU2013390806A1 (en) 2015-12-24
US9446142B2 (en) 2016-09-20

Similar Documents

Publication Publication Date Title
AU2013390806B2 (en) Polymer chelator conjugates
AU2009293001B2 (en) Bionanocomposite for tissue regeneration and soft tissue repair
CN102256609B (zh) 衍生自前胃胞外基质的组织支架
US12076348B2 (en) Micronized placental compositions comprising a chelator
CN108473632B (zh) 聚合组合物
CN105228665A (zh) 抗血栓形成移植物
KR20070106696A (ko) 이식가능한 바이오물질 및 그 제조 방법
Bankoti et al. Dual functionalized injectable hybrid extracellular matrix hydrogel for burn wounds
Zhao et al. A sustained H2S-releasing nanocellulose-based hydrogel with anti-inflammatory and antibacterial properties for promoting infected wound healing
CN102477172B (zh) 壳聚糖-肝素纳米颗粒以及用该纳米颗粒处理的去细胞基质的生物材料
Liu et al. Nanocomposite hydrogel with multiple metal ions coupling for effective treatment of bacteria infected wound via cascade catalysis and tissue regeneration
EP3698814B1 (en) Composition for surface modification of medical implant and medical implant surface-modified thereby
Liu et al. Polyamino acid antibacterial hydrogel with photothermal effect for wound healing
Zheng et al. In situ cross-linked collagen-based biological patch integrating anti-infection and anti-calcification properties
Balaji et al. Engineering Antioxidant and Oxygen-Releasing Lignin Composites to Accelerate Wound Healing
Chen et al. CuSO4/H2O2 induced polydopamine/polysulfobetaine methacrylate co-deposition on poly (amino acid) membranes for improved anti-protein adsorption and antibacterial activity
Ma et al. Chitosan and ibuprofen grafted electrospun polylactic acid/gelatin membrane mitigates inflammatory response
Hu et al. Multifunctional hydrogel with dynamic phase-adaptive regulation for expediting infected diabetic wound repair
Zhu et al. Bioprosthetic heart valves with zwitterionic copolymer grafting to improve the properties of endothelialization and anti-calcification
CN120053761A (zh) 一种生物补片及其制备方法和用途
Whelove Development of Gold Nanoparticle Conjugated Polyethylene Terephthalate for Improved Biocompatibility in Hernia Repair Materials

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)