AU2013256064B2 - Pharmaceutical nanoparticles showing improved mucosal transport - Google Patents

Pharmaceutical nanoparticles showing improved mucosal transport Download PDF

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Publication number
AU2013256064B2
AU2013256064B2 AU2013256064A AU2013256064A AU2013256064B2 AU 2013256064 B2 AU2013256064 B2 AU 2013256064B2 AU 2013256064 A AU2013256064 A AU 2013256064A AU 2013256064 A AU2013256064 A AU 2013256064A AU 2013256064 B2 AU2013256064 B2 AU 2013256064B2
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Australia
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kda
particles
polymer
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AU2013256064A1 (en
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Alexey Popov
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Alcon Inc
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Alcon Inc
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Priority to AU2018202074A priority Critical patent/AU2018202074B2/en
Priority to AU2020201184A priority patent/AU2020201184B2/en
Assigned to ALCON INC. reassignment ALCON INC. Request for Assignment Assignors: KALA PHARMACEUTICALS, INC.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AU2013256064A 2012-05-03 2013-05-03 Pharmaceutical nanoparticles showing improved mucosal transport Active AU2013256064B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2018202074A AU2018202074B2 (en) 2012-05-03 2018-03-23 Pharmaceutical nanoparticles showing improved mucosal transport
AU2020201184A AU2020201184B2 (en) 2012-05-03 2020-02-19 Pharmaceutical nanoparticles showing improved mucosal transport

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261642261P 2012-05-03 2012-05-03
US61/642,261 2012-05-03
PCT/US2013/039499 WO2013166408A1 (en) 2012-05-03 2013-05-03 Pharmaceutical nanoparticles showing improved mucosal transport

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2018202074A Division AU2018202074B2 (en) 2012-05-03 2018-03-23 Pharmaceutical nanoparticles showing improved mucosal transport

Publications (2)

Publication Number Publication Date
AU2013256064A1 AU2013256064A1 (en) 2014-10-30
AU2013256064B2 true AU2013256064B2 (en) 2018-01-04

Family

ID=48446664

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2013256064A Active AU2013256064B2 (en) 2012-05-03 2013-05-03 Pharmaceutical nanoparticles showing improved mucosal transport
AU2018202074A Active AU2018202074B2 (en) 2012-05-03 2018-03-23 Pharmaceutical nanoparticles showing improved mucosal transport
AU2020201184A Active AU2020201184B2 (en) 2012-05-03 2020-02-19 Pharmaceutical nanoparticles showing improved mucosal transport

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2018202074A Active AU2018202074B2 (en) 2012-05-03 2018-03-23 Pharmaceutical nanoparticles showing improved mucosal transport
AU2020201184A Active AU2020201184B2 (en) 2012-05-03 2020-02-19 Pharmaceutical nanoparticles showing improved mucosal transport

Country Status (8)

Country Link
US (3) US10688041B2 (ja)
EP (2) EP2844227B1 (ja)
JP (4) JP6360040B2 (ja)
KR (1) KR102154880B1 (ja)
AU (3) AU2013256064B2 (ja)
CA (1) CA2871745C (ja)
HK (1) HK1208160A1 (ja)
WO (1) WO2013166408A1 (ja)

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US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
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US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
EP2844227B1 (en) 2012-05-03 2020-11-18 Kala Pharmaceuticals, Inc. Pharmaceutical nanoparticles showing improved mucosal transport
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US10568975B2 (en) 2013-02-05 2020-02-25 The Johns Hopkins University Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof
US9987233B2 (en) 2013-03-21 2018-06-05 Eupraxia Pharmaceuticals USA LLC Injectable sustained release composition and method of using the same for treating inflammation in joints and pain associated therewith
KR102027663B1 (ko) 2013-05-06 2019-10-01 가오슝 창 궁 메모리얼 하스피털 약학적 조성물 및 이의 용도
JP6426194B2 (ja) 2013-11-01 2018-11-21 カラ ファーマシューティカルズ インコーポレイテッド 治療用化合物の結晶形態及びその使用
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CN112367974A (zh) * 2018-05-15 2021-02-12 DNALite治疗学公司 粘液穿透肽、递送媒介和治疗方法
JP2021535112A (ja) 2018-08-20 2021-12-16 アキリオン ファーマシューティカルズ，インコーポレーテッド 補体ｄ因子の医学的障害の治療のための医薬化合物
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