AU2013230425B2 - Substituted heterocyclic acetamides as kappa opioid receptor (kor) agonists - Google Patents

Substituted heterocyclic acetamides as kappa opioid receptor (kor) agonists Download PDF

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AU2013230425B2
AU2013230425B2 AU2013230425A AU2013230425A AU2013230425B2 AU 2013230425 B2 AU2013230425 B2 AU 2013230425B2 AU 2013230425 A AU2013230425 A AU 2013230425A AU 2013230425 A AU2013230425 A AU 2013230425A AU 2013230425 B2 AU2013230425 B2 AU 2013230425B2
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ethyl
hydroxypyrrolidin
methyl
oxo
acetamide
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AU2013230425A1 (en
Inventor
Yonghua Gai
Vijay Potluri
Pradip Kumar Sasmal
Ashok Tehim
Chintakunta VAMSEEKRISHNA
Hang Zhang
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Dr Reddys Laboratories Ltd
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Dr Reddys Laboratories Ltd
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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AU2013230425A 2012-03-05 2013-03-05 Substituted heterocyclic acetamides as kappa opioid receptor (kor) agonists Ceased AU2013230425B2 (en)

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US201261606632P 2012-03-05 2012-03-05
US61/606,632 2012-03-05
PCT/CN2013/000230 WO2013131408A1 (en) 2012-03-05 2013-03-05 Substituted heterocyclic acetamides as kappa opioid receptor (kor) agonists

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KR (1) KR101773331B1 (enExample)
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CA2805839C (en) 2010-07-22 2019-01-15 K-Fee System Gmbh Portion capsule having an identifier
MX355142B (es) * 2012-03-05 2018-04-05 Dr Reddys Laboratories Ltd Acetamidas heterociclicas sustituidas como agonistas del receptor opioide kappa (kor).
CN103664727A (zh) * 2013-12-19 2014-03-26 无锡万全医药技术有限公司 一种一锅法制备1-[(3s)-3-羟基吡咯烷-1-基]-(2s)-2-甲氨基-2-苯基乙烷的工艺
CN103772257A (zh) * 2013-12-31 2014-05-07 无锡万全医药技术有限公司 一种制备2-((3s)-3-羟基吡咯烷-1-基)-(1s)-1-苯乙基氨基甲酸酯的方法
MX2016009624A (es) * 2014-01-24 2016-11-08 Cadila Healthcare Ltd Compuestos heterobiciclicos novedosos como agonistas del opioide kappa.
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