AU2012325697B2 - Point-of care immunoassay for quantitative small analyte detection - Google Patents
Point-of care immunoassay for quantitative small analyte detection Download PDFInfo
- Publication number
- AU2012325697B2 AU2012325697B2 AU2012325697A AU2012325697A AU2012325697B2 AU 2012325697 B2 AU2012325697 B2 AU 2012325697B2 AU 2012325697 A AU2012325697 A AU 2012325697A AU 2012325697 A AU2012325697 A AU 2012325697A AU 2012325697 B2 AU2012325697 B2 AU 2012325697B2
- Authority
- AU
- Australia
- Prior art keywords
- analyte
- capture
- binding
- sample
- assay
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1048—SELEX
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54388—Immunochromatographic test strips based on lateral flow
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
- G01N2470/04—Sandwich assay format
- G01N2470/06—Second binding partner specifically binding complex of analyte with first binding partner
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2016200720A AU2016200720A1 (en) | 2011-10-21 | 2016-02-04 | Point-of care immunoassay for quantitative small analyte detection |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161550141P | 2011-10-21 | 2011-10-21 | |
| US61/550,141 | 2011-10-21 | ||
| US201261637143P | 2012-04-23 | 2012-04-23 | |
| US61/637,143 | 2012-04-23 | ||
| PCT/US2012/061354 WO2013059805A1 (en) | 2011-10-21 | 2012-10-22 | Point-of care immunoassay for quantitative small analyte detection |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2016200720A Division AU2016200720A1 (en) | 2011-10-21 | 2016-02-04 | Point-of care immunoassay for quantitative small analyte detection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2012325697A1 AU2012325697A1 (en) | 2014-05-22 |
| AU2012325697B2 true AU2012325697B2 (en) | 2015-11-26 |
Family
ID=47116496
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012325697A Active AU2012325697B2 (en) | 2011-10-21 | 2012-10-22 | Point-of care immunoassay for quantitative small analyte detection |
| AU2016200720A Abandoned AU2016200720A1 (en) | 2011-10-21 | 2016-02-04 | Point-of care immunoassay for quantitative small analyte detection |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2016200720A Abandoned AU2016200720A1 (en) | 2011-10-21 | 2016-02-04 | Point-of care immunoassay for quantitative small analyte detection |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20130102003A1 (https=) |
| EP (1) | EP2769219B1 (https=) |
| JP (2) | JP2014531031A (https=) |
| AU (2) | AU2012325697B2 (https=) |
| CA (1) | CA2853103C (https=) |
| WO (1) | WO2013059805A1 (https=) |
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|---|---|---|---|---|
| US10101324B2 (en) | 2012-12-03 | 2018-10-16 | The Regents Of The University Of California | Non-competitive immunoassays to detect small molecules using nanopeptamers |
| CA3042642A1 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| CN105705938B (zh) | 2013-08-19 | 2020-11-06 | 休斯敦大学系统 | 磷光报告物 |
| US20150064672A1 (en) * | 2013-09-05 | 2015-03-05 | Matthew Bars | Systems and methods for treatment of substance addiction |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US10172797B2 (en) | 2013-12-17 | 2019-01-08 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US10648974B2 (en) | 2014-05-28 | 2020-05-12 | Carehealth America Corporation | Ethyl glucuronide lateral flow test strips, immunoassays, devices and methods for detecting or measuring thereof |
| CA2955229C (en) | 2014-07-17 | 2020-03-10 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
| GB2528657B (en) * | 2014-07-24 | 2019-03-13 | Intelligent Fingerprinting Ltd | Sample analysing device |
| AU2015336065A1 (en) | 2014-10-20 | 2017-05-04 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| EP3256856A4 (en) * | 2014-12-17 | 2018-06-06 | Singulex, Inc. | Multiplexed single molecule analyzer |
| BR112017021305A2 (pt) * | 2015-04-06 | 2018-06-26 | Bludiagnostics Inc | dispositivo de teste de fluxo lateral, e, método e kit para detecção quantitativa de um analito em uma amostra de saliva |
| WO2016198987A1 (en) * | 2015-06-10 | 2016-12-15 | Abs Advanced Biomedical Systems S.R.L. | Device and method for immunochromatographic assay |
| EA037478B1 (ru) | 2015-08-04 | 2021-04-01 | Дьюк Юниверсити | Генетически кодируемые внутренне неупорядоченные полимеры-"невидимки" для доставки и способы их применения |
| US11752213B2 (en) | 2015-12-21 | 2023-09-12 | Duke University | Surfaces having reduced non-specific binding and antigenicity |
| WO2017170824A1 (ja) * | 2016-03-31 | 2017-10-05 | 積水メディカル株式会社 | 簡易免疫測定を利用した癌胎児性フィブロネクチンの検出方法 |
| WO2017210476A1 (en) | 2016-06-01 | 2017-12-07 | Duke University | Nonfouling biosensors |
| EP3508851A4 (en) * | 2016-08-31 | 2020-07-29 | Sekisui Chemical Co., Ltd. | FLUORESCENT PARTICLES FOR A DIAGNOSIS AGENT AND IMMUNOLOGICAL ASSAY REAGENT USER |
| JP2020500150A (ja) | 2016-09-23 | 2020-01-09 | デューク ユニバーシティ | 下限臨界溶液温度挙動を有する非反復かつ非構造的ポリペプチド |
| WO2018132732A1 (en) | 2017-01-12 | 2018-07-19 | Duke University | Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly |
| WO2018193592A1 (ja) * | 2017-04-20 | 2018-10-25 | 株式会社キュア・アップ | 禁煙患者のためのプログラム、装置、システム及び方法 |
| WO2018213320A1 (en) | 2017-05-15 | 2018-11-22 | Duke University | Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents |
| KR102582297B1 (ko) | 2017-05-19 | 2023-09-25 | 필립모리스 프로덕츠 에스.에이. | 대상체의 흡연 상태를 구별하기 위한 진단 테스트 |
| WO2019006374A1 (en) | 2017-06-30 | 2019-01-03 | Duke University | ORDER AND DISORDER AS A DESIGN PRINCIPLE FOR STIMULI-SENSITIVE BIOPOLYMER NETWORKS |
| WO2019018697A1 (en) | 2017-07-19 | 2019-01-24 | Evanostics, Llc | CARTRIDGES FOR ORAL FLUID ANALYSIS AND METHODS OF USE |
| EP3665187A4 (en) * | 2017-08-08 | 2021-04-21 | OraSure Technologies, Inc. | TEST PROCEDURES FOR IMPROVED ANALYTE DETECTION |
| US11262367B2 (en) | 2017-12-15 | 2022-03-01 | Evanostics Llc | Optical reader for analyte testing |
| WO2019147954A1 (en) | 2018-01-26 | 2019-08-01 | Duke University | Albumin binding peptide-drug (aibiped) conjugates and methods of making and using same |
| EP3788343B1 (en) | 2018-04-30 | 2024-03-27 | Duke University | Stimuli-responsive peg-like polymer-based drug delivery platform |
| JP7151987B2 (ja) * | 2018-05-09 | 2022-10-12 | 株式会社Cureapp | 禁煙患者のためのプログラム、装置、システム及び方法 |
| US11649275B2 (en) | 2018-08-02 | 2023-05-16 | Duke University | Dual agonist fusion proteins |
| IT201800008274A1 (it) * | 2018-08-31 | 2020-03-02 | Alifax Srl | Metodo immunometrico per analisi cliniche biologiche |
| US12594347B2 (en) | 2018-09-07 | 2026-04-07 | Duke University | Nanoparticulate drug delivery systems |
| US12066383B2 (en) | 2018-12-18 | 2024-08-20 | Aspida Dx Inc. | Optical analyte detection |
| US11512314B2 (en) | 2019-07-12 | 2022-11-29 | Duke University | Amphiphilic polynucleotides |
| CN114631025A (zh) * | 2019-08-29 | 2022-06-14 | 米雷亚·C·阿罗诺维茨 | 侧向流动免疫化学中的定量分析物检测 |
| CN110672834A (zh) * | 2019-09-26 | 2020-01-10 | 北京丹大生物技术有限公司 | 一种快速检测样品中铅含量的试剂盒 |
| CN112029771B (zh) * | 2019-11-13 | 2021-12-14 | 安徽省昂普拓迈生物科技有限责任公司 | 一种特异性结合哌替啶的核酸适配体及其应用 |
| WO2024173482A2 (en) * | 2023-02-14 | 2024-08-22 | North Carolina State University | Compositions and methods related to aptamer-based sensors |
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| EP0232357B1 (en) | 1985-08-05 | 1991-01-30 | Rijksuniversiteit Leiden | Labelled macromolecules; a process for their preparation and their use for immunological or immunocytochemical assays |
| US5846713A (en) | 1990-06-11 | 1998-12-08 | Nexstar Pharmaceuticals, Inc. | High affinity HKGF nucleic acid ligands and inhibitors |
| US5660985A (en) | 1990-06-11 | 1997-08-26 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands containing modified nucleotides |
| US5503978A (en) | 1990-06-11 | 1996-04-02 | University Research Corporation | Method for identification of high affinity DNA ligands of HIV-1 reverse transcriptase |
| US5780228A (en) | 1990-06-11 | 1998-07-14 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands to lectins |
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| US5795721A (en) | 1990-06-11 | 1998-08-18 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands of ICP4 |
| US5731424A (en) | 1990-06-11 | 1998-03-24 | Nexstar Pharmaceuticals, Inc. | High affinity TGFβ nucleic acid ligands and inhibitors |
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| US6013443A (en) | 1995-05-03 | 2000-01-11 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: tissue SELEX |
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| DE19622503C2 (de) * | 1996-06-05 | 1998-07-09 | Securetec Sicherheitstechnolog | Verfahren zum Nachweis von Analyten auf einer Oberfläche |
| US5792613A (en) | 1996-06-12 | 1998-08-11 | The Curators Of The University Of Missouri | Method for obtaining RNA aptamers based on shape selection |
| US6051698A (en) | 1997-06-06 | 2000-04-18 | Janjic; Nebojsa | Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes |
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| SG169395A1 (en) * | 2006-02-09 | 2011-03-30 | Univ South Florida | Detection of cancer by elevated levels of bcl-2 |
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| GB0605965D0 (en) * | 2006-03-24 | 2006-05-03 | Univ East Anglia | Fluorescence based detection of substances |
| JP4698559B2 (ja) * | 2006-11-24 | 2011-06-08 | Necソフト株式会社 | ウサギ由来のIgG抗体に結合性を有する核酸分子 |
| CA2671872A1 (en) * | 2006-12-07 | 2008-06-12 | University Of Florida Research Foundation, Inc. | Materials and methods for efficient and accurate detection of analytes |
| JP2009189310A (ja) * | 2008-02-15 | 2009-08-27 | Olympus Corp | 高親和性核酸フラグメント群の塩基配列決定方法および核酸アプタマーのスクリーニング方法 |
| JP2009195187A (ja) * | 2008-02-22 | 2009-09-03 | Olympus Corp | 核酸アプタマーのスクリーニング方法 |
| AU2010248380B2 (en) * | 2009-05-15 | 2013-12-19 | Nec Solution Innovators, Ltd. | Aptamer that recognizes peptide |
| US9476891B2 (en) * | 2009-07-21 | 2016-10-25 | Sekisui Medical Co., Ltd. | Insulin assay |
| JP6041373B2 (ja) * | 2010-02-01 | 2016-12-07 | Necソリューションイノベータ株式会社 | TNF−αに結合するアプタマー分子 |
-
2012
- 2012-10-22 AU AU2012325697A patent/AU2012325697B2/en active Active
- 2012-10-22 WO PCT/US2012/061354 patent/WO2013059805A1/en not_active Ceased
- 2012-10-22 CA CA2853103A patent/CA2853103C/en active Active
- 2012-10-22 US US13/657,625 patent/US20130102003A1/en not_active Abandoned
- 2012-10-22 EP EP12780383.1A patent/EP2769219B1/en active Active
- 2012-10-22 JP JP2014537362A patent/JP2014531031A/ja active Pending
-
2016
- 2016-02-04 AU AU2016200720A patent/AU2016200720A1/en not_active Abandoned
-
2017
- 2017-04-05 JP JP2017075025A patent/JP2017138325A/ja active Pending
-
2018
- 2018-12-20 US US16/227,844 patent/US20190204309A1/en not_active Abandoned
Non-Patent Citations (2)
| Title |
|---|
| CHO, E. J. et al., Annu. Rev. Anal. Chem., 2009, Vol. 2, pages 241-264 * |
| JAYASENA, S. D., Clincal Chemistry, Vol. 45, No. 9, pages 1628-1650 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012325697A1 (en) | 2014-05-22 |
| JP2014531031A (ja) | 2014-11-20 |
| US20130102003A1 (en) | 2013-04-25 |
| EP2769219B1 (en) | 2017-08-30 |
| EP2769219A1 (en) | 2014-08-27 |
| CA2853103A1 (en) | 2013-04-25 |
| HK1201577A1 (en) | 2015-09-04 |
| WO2013059805A1 (en) | 2013-04-25 |
| CA2853103C (en) | 2020-01-07 |
| US20190204309A1 (en) | 2019-07-04 |
| JP2017138325A (ja) | 2017-08-10 |
| AU2016200720A1 (en) | 2016-02-25 |
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