AU2012310342B2 - Preparation method of 1-palmitoyl-3-acetylglycerol, and preparation method of 1-palmitoyl-2-linoleoyl-3-acetylglycerol using same - Google Patents
Preparation method of 1-palmitoyl-3-acetylglycerol, and preparation method of 1-palmitoyl-2-linoleoyl-3-acetylglycerol using same Download PDFInfo
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- AU2012310342B2 AU2012310342B2 AU2012310342A AU2012310342A AU2012310342B2 AU 2012310342 B2 AU2012310342 B2 AU 2012310342B2 AU 2012310342 A AU2012310342 A AU 2012310342A AU 2012310342 A AU2012310342 A AU 2012310342A AU 2012310342 B2 AU2012310342 B2 AU 2012310342B2
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- Australia
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- palmitoyl
- acetylglycerol
- preparing
- linoleoyl
- amount
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/307—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/10—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
- C07C67/52—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
- C07C69/22—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
- C07C69/30—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with trihydroxylic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020110096341A KR101278874B1 (ko) | 2011-09-23 | 2011-09-23 | 1-팔미토일-3-아세틸글리세롤의 제조방법 및 이를 이용한 1-팔미토일-2-리놀레오일-3-아세틸글리세롤의 제조방법 |
| KR10-2011-0096341 | 2011-09-23 | ||
| PCT/KR2012/007644 WO2013043009A2 (ko) | 2011-09-23 | 2012-09-24 | 1-팔미토일-3-아세틸글리세롤의 제조방법 및 이를 이용한 1-팔미토일-2-리놀레오일-3-아세틸글리세롤의 제조방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2012310342A1 AU2012310342A1 (en) | 2014-04-03 |
| AU2012310342B2 true AU2012310342B2 (en) | 2015-11-26 |
Family
ID=47915041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012310342A Active AU2012310342B2 (en) | 2011-09-23 | 2012-09-24 | Preparation method of 1-palmitoyl-3-acetylglycerol, and preparation method of 1-palmitoyl-2-linoleoyl-3-acetylglycerol using same |
Country Status (11)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101278874B1 (ko) | 2011-09-23 | 2013-06-26 | 주식회사 엔지켐생명과학 | 1-팔미토일-3-아세틸글리세롤의 제조방법 및 이를 이용한 1-팔미토일-2-리놀레오일-3-아세틸글리세롤의 제조방법 |
| CN105658213A (zh) | 2013-08-19 | 2016-06-08 | Enzychem生命科学株式会社 | 含有以单乙酰基二酰基甘油化合物作为有效成分的哮喘的预防或者治疗用组合物 |
| US9808438B2 (en) | 2015-11-09 | 2017-11-07 | Enzychem Lifesciences Corporation | Method for treating mucositis |
| US10555923B2 (en) | 2015-11-14 | 2020-02-11 | Enzychem Lifesciences Corporation | Method for treating paroxysmal nocturnal hemoglobinuria |
| US10653657B2 (en) | 2015-11-14 | 2020-05-19 | Enzychem Lifesciences Corporation | Method for treating hemolytic uremic syndrome |
| WO2019106632A1 (en) | 2017-11-30 | 2019-06-06 | Enzychem Lifesciences Corporation | Compositions for prevention or treatment of acute radiation syndrome |
| KR102333606B1 (ko) | 2019-10-15 | 2021-12-01 | 주식회사 엔지켐생명과학 | 1-팔미토일-2-리놀레오일-3-아세틸 글리세롤의 제조 방법 |
| RU2758793C1 (ru) * | 2021-03-29 | 2021-11-01 | Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Образования «Новосибирский Государственный Технический Университет» | Адаптивная стартер-генераторная система |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0694438B2 (ja) * | 1985-11-06 | 1994-11-24 | 株式会社ツムラ | 新規なグリセリン誘導体 |
| JPH0694438A (ja) | 1992-09-14 | 1994-04-05 | Matsushita Electric Works Ltd | 光切断法による外観検査装置 |
| JP3408337B2 (ja) * | 1994-10-05 | 2003-05-19 | 花王株式会社 | グリセリン誘導体の製造法 |
| JPH09110787A (ja) * | 1995-10-11 | 1997-04-28 | Hoechst Japan Ltd | 無溶媒反応による１級アルコールとフェノールのアセチル化方法 |
| DK0847994T3 (da) * | 1996-12-11 | 2003-07-28 | Hoffmann La Roche | Fremgangsmåde til fremstilling af blandede anhydrider |
| KR100283010B1 (ko) | 1997-11-20 | 2001-04-02 | 전길자 | 녹용 추출물을 함유하는 조혈모세포 및 혈소판 전구세포 증식촉진용 조성물 |
| KR100291743B1 (ko) | 1997-11-20 | 2001-05-15 | 전길자 | 글리세롤 유도체의 제조방법 |
| DE69833333T2 (de) * | 1997-11-20 | 2006-10-19 | Jhon, Gil Ja | Pharmazeutische zusammensetzung enthaltend geweihextrakte von cervus nippon mit wachstumsstimulierender aktivität auf hematopoietische stammzellen und megakaryozyten |
| KR20010008387A (ko) * | 2000-11-30 | 2001-02-05 | 이성권 | 결정화방법을 이용한 고순도 불포화지방산의 분리 정제 방법 |
| WO2005090274A1 (en) * | 2004-03-22 | 2005-09-29 | Enzychem Co., Ltd | Process for regioselective preparation of glycerol, derivative and intermediate therefor |
| KR20050118057A (ko) * | 2004-04-24 | 2005-12-15 | 김상희 | 아세틸디아실글리세롤류의 화합물을 유효성분으로함유하는 항암제 및 건강식품 |
| KR100789323B1 (ko) * | 2005-07-20 | 2007-12-28 | 주식회사 엔지켐 | 글리세롤 유도체의 위치 선택적 제조방법 및 그 중간체 |
| WO2010006261A1 (en) * | 2008-07-10 | 2010-01-14 | Hong John J | Methods for inducing stem cell migration and specialization with ec-18 |
| KR101278874B1 (ko) | 2011-09-23 | 2013-06-26 | 주식회사 엔지켐생명과학 | 1-팔미토일-3-아세틸글리세롤의 제조방법 및 이를 이용한 1-팔미토일-2-리놀레오일-3-아세틸글리세롤의 제조방법 |
| JP6094438B2 (ja) | 2013-09-27 | 2017-03-15 | トヨタ自動車株式会社 | 内燃機関の制御装置 |
-
2011
- 2011-09-23 KR KR1020110096341A patent/KR101278874B1/ko active Active
-
2012
- 2012-09-24 RU RU2014116232/04A patent/RU2566826C1/ru active
- 2012-09-24 IN IN2166DEN2014 patent/IN2014DN02166A/en unknown
- 2012-09-24 US US14/346,783 patent/US20140243548A1/en not_active Abandoned
- 2012-09-24 CA CA2849289A patent/CA2849289C/en active Active
- 2012-09-24 JP JP2014531727A patent/JP5799171B2/ja active Active
- 2012-09-24 CN CN201280046277.7A patent/CN103827075B/zh active Active
- 2012-09-24 AU AU2012310342A patent/AU2012310342B2/en active Active
- 2012-09-24 EP EP12834214.4A patent/EP2759529B1/en active Active
- 2012-09-24 WO PCT/KR2012/007644 patent/WO2013043009A2/ko active Application Filing
- 2012-09-24 ES ES12834214.4T patent/ES2620103T3/es active Active
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2015
- 2015-12-03 US US14/958,734 patent/US9701613B2/en active Active
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2017
- 2017-03-03 US US15/448,728 patent/US20170183287A1/en not_active Abandoned
Non-Patent Citations (5)
| Title |
|---|
| Craven RJ and Lencki RW "Preparation of diacid 1,3-diacylglycerols" Journal of the American Oil Chemists' Society. 2010 Vol 87 pages 1281-1291 * |
| Han S-Y et al. "Monoacetyldiglycerides as new Ca2+ mobilizing agents in rat pancreatic acinar cells" Bioorganic and Medicinal Chemistry Letters. 1999 vol 9 pages 59-64 * |
| Martin JB and Lutton ES "Preparation and phase behaviour of acetyl monoglycerides" Journal of the American Oil Chemists' Society. 1972 Vol 49 pages 683-687 * |
| Suh JS et al. Cellular Physiology and Biochemistry. 2003 Vol 13 pages 415-422 * |
| Vicknair EJ et al. "Some physical properties of the polymorphic forms of 1,2-diaceto-3-stearin and 1- aceto-3-stearin" Journal of Physical Chemistry. 1954 Vol 58 pages 64-66 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013043009A3 (ko) | 2013-05-30 |
| RU2566826C1 (ru) | 2015-10-27 |
| US20140243548A1 (en) | 2014-08-28 |
| CN103827075A (zh) | 2014-05-28 |
| US9701613B2 (en) | 2017-07-11 |
| US20160083329A1 (en) | 2016-03-24 |
| ES2620103T3 (es) | 2017-06-27 |
| CA2849289C (en) | 2016-05-10 |
| CN103827075B (zh) | 2015-09-16 |
| JP5799171B2 (ja) | 2015-10-21 |
| CA2849289A1 (en) | 2013-03-28 |
| KR20130032628A (ko) | 2013-04-02 |
| US20170183287A1 (en) | 2017-06-29 |
| IN2014DN02166A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2015-05-15 |
| AU2012310342A1 (en) | 2014-04-03 |
| EP2759529A4 (en) | 2015-05-20 |
| EP2759529B1 (en) | 2016-12-21 |
| EP2759529A2 (en) | 2014-07-30 |
| WO2013043009A2 (ko) | 2013-03-28 |
| JP2014528945A (ja) | 2014-10-30 |
| KR101278874B1 (ko) | 2013-06-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |