AU2012214285A1 - Purification of triglyceride oil from microbial sources using short path distillation - Google Patents
Purification of triglyceride oil from microbial sources using short path distillation Download PDFInfo
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- AU2012214285A1 AU2012214285A1 AU2012214285A AU2012214285A AU2012214285A1 AU 2012214285 A1 AU2012214285 A1 AU 2012214285A1 AU 2012214285 A AU2012214285 A AU 2012214285A AU 2012214285 A AU2012214285 A AU 2012214285A AU 2012214285 A1 AU2012214285 A1 AU 2012214285A1
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- Prior art keywords
- sterol
- oil
- acid
- microbial
- biomass
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- 230000008520 organization Effects 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 238000012261 overproduction Methods 0.000 description 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 description 1
- BHAAPTBBJKJZER-UHFFFAOYSA-N p-anisidine Chemical compound COC1=CC=C(N)C=C1 BHAAPTBBJKJZER-UHFFFAOYSA-N 0.000 description 1
- IPCSVZSSVZVIGE-UHFFFAOYSA-N palmitic acid group Chemical group C(CCCCCCCCCCCCCCC)(=O)O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 150000002978 peroxides Chemical class 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 150000008103 phosphatidic acids Chemical class 0.000 description 1
- 229940067626 phosphatidylinositols Drugs 0.000 description 1
- 150000003905 phosphatidylinositols Chemical class 0.000 description 1
- 229950004354 phosphorylcholine Drugs 0.000 description 1
- PYJNAPOPMIJKJZ-UHFFFAOYSA-N phosphorylcholine chloride Chemical compound [Cl-].C[N+](C)(C)CCOP(O)(O)=O PYJNAPOPMIJKJZ-UHFFFAOYSA-N 0.000 description 1
- 150000003019 phosphosphingolipids Chemical class 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 125000000830 polyketide group Chemical group 0.000 description 1
- 150000003096 polyprenols Chemical class 0.000 description 1
- 239000000583 progesterone congener Substances 0.000 description 1
- 229940095055 progestogen systemic hormonal contraceptives Drugs 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
- 150000004053 quinones Chemical class 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 230000008844 regulatory mechanism Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 150000003313 saccharo lipids Chemical class 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000007127 saponification reaction Methods 0.000 description 1
- 238000013341 scale-up Methods 0.000 description 1
- 150000003338 secosteroids Chemical class 0.000 description 1
- 238000011218 seed culture Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 150000004666 short chain fatty acids Chemical class 0.000 description 1
- 230000019491 signal transduction Effects 0.000 description 1
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- WWUZIQQURGPMPG-KRWOKUGFSA-N sphingosine Chemical compound CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)CO WWUZIQQURGPMPG-KRWOKUGFSA-N 0.000 description 1
- 229940031439 squalene Drugs 0.000 description 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 229940037128 systemic glucocorticoids Drugs 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 229940040944 tetracyclines Drugs 0.000 description 1
- 150000003595 thromboxanes Chemical class 0.000 description 1
- 150000005691 triesters Chemical class 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 238000002137 ultrasound extraction Methods 0.000 description 1
- 238000000825 ultraviolet detection Methods 0.000 description 1
- 238000010977 unit operation Methods 0.000 description 1
- 229940035893 uracil Drugs 0.000 description 1
- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 description 1
- 229940045145 uridine Drugs 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
- 235000019386 wax ester Nutrition 0.000 description 1
- 239000012130 whole-cell lysate Substances 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
- B01D3/12—Molecular distillation
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B1/00—Production of fats or fatty oils from raw materials
- C11B1/10—Production of fats or fatty oils from raw materials by extracting
- C11B1/104—Production of fats or fatty oils from raw materials by extracting using super critical gases or vapours
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B3/00—Refining fats or fatty oils
- C11B3/12—Refining fats or fatty oils by distillation
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161441842P | 2011-02-11 | 2011-02-11 | |
| US61/441,842 | 2011-02-11 | ||
| PCT/US2012/024687 WO2012109563A1 (en) | 2011-02-11 | 2012-02-10 | Purification of triglyceride oil from microbial sources using short path distillation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2012214285A1 true AU2012214285A1 (en) | 2013-07-18 |
Family
ID=46638975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012214285A Abandoned AU2012214285A1 (en) | 2011-02-11 | 2012-02-10 | Purification of triglyceride oil from microbial sources using short path distillation |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9040730B2 (enExample) |
| EP (1) | EP2673063A1 (enExample) |
| JP (1) | JP2014510166A (enExample) |
| CN (1) | CN103379946A (enExample) |
| AU (1) | AU2012214285A1 (enExample) |
| CA (1) | CA2824776A1 (enExample) |
| WO (1) | WO2012109563A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2825039C (en) * | 2011-02-11 | 2020-04-28 | E.I. Du Pont De Nemours And Company | Method for obtaining a lipid-containing composition from microbial biomass |
| US9074160B2 (en) * | 2013-03-07 | 2015-07-07 | Algisys, Llc | Production of omega-3 fatty acids from pythium species |
| ES2872449T3 (es) * | 2013-12-04 | 2021-11-02 | Nippon Suisan Kaisha Ltd | Aceite microbiano, procedimiento para fabricar aceite microbiano, aceite microbiano concentrado y procedimiento para fabricar aceite microbiano concentrado |
| FR3025216A1 (fr) * | 2014-09-03 | 2016-03-04 | Univ Toulouse 3 Paul Sabatier | Procede d'extraction de lipide par electropulsation |
| CN106318984B (zh) * | 2015-06-30 | 2020-11-17 | 中国科学院大连化学物理研究所 | 一种产油微生物制脂肪酸甘油脂的方法及其甘油脂和应用 |
| US10406451B2 (en) | 2017-08-24 | 2019-09-10 | Lab Society Llc | High efficiency distillation head and methods of use |
| US10751638B2 (en) | 2017-03-03 | 2020-08-25 | Lab Society Llc | High efficiency distillation head and methods of use |
| KR102747178B1 (ko) | 2018-04-25 | 2024-12-27 | 누시드 뉴트리셔널 유에스 아이엔씨. | Dha가 풍부한 다중불포화된 지방산 조성물 |
| PL3560342T3 (pl) | 2018-04-25 | 2021-02-22 | Nuseed Nutritional Us Inc. | Kompozycje wielonienasyconych kwasów tłuszczowych wzbogacone w dha |
| EP3586641A1 (en) | 2018-06-21 | 2020-01-01 | Nuseed Pty Ltd | Dha enriched polyunsaturated fatty acid compositions |
| EP3586640A1 (en) | 2018-06-21 | 2020-01-01 | Nuseed Pty Ltd | Dha enriched polyunsaturated fatty acid compositions |
| EP3586643A1 (en) | 2018-06-21 | 2020-01-01 | Nuseed Pty Ltd | Dha enriched polyunsaturated fatty acid compositions |
| EP3586642A1 (en) | 2018-06-21 | 2020-01-01 | Nuseed Pty Ltd | Ala enriched polyunsaturated fatty acid compositions |
| LV15474B (lv) * | 2018-06-29 | 2020-07-20 | Rīgas Tehniskā Universitāte | Vienšūņu eļļas iegūšanas paņēmiens no biodegradējamiem ražošanas atkritumiem |
| CN115968405A (zh) * | 2020-02-10 | 2023-04-14 | C16生物科学有限公司 | 微生物生产的棕榈油替代品 |
| EP4243627A4 (en) * | 2020-11-12 | 2024-10-16 | C16 Biosciences, Inc. | Edible microbial oil |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2874171A (en) * | 1957-02-20 | 1959-02-17 | Upjohn Co | Recovery of ergosterol |
| US4293220A (en) * | 1979-07-02 | 1981-10-06 | The United States Of America As Represented By The Secretary Of The Navy | Application of inductively coupled plasma emission spectrometry to the elemental analysis of organic compounds and to the determination of the empirical formulas for these and other compounds |
| DE3783396T2 (de) * | 1986-07-08 | 1993-07-29 | Suntory Ltd | Verfahren zur herstellung von bishomo-gamma-linolensaeure und eicosapentaensaeure. |
| EP0442184A1 (en) | 1990-02-15 | 1991-08-21 | Campbell Soup Company | Production of low cholesterol animal fat by short path distillation |
| US6166230A (en) * | 1996-05-15 | 2000-12-26 | Gist-Brocades B.V. | Sterol extraction with polar solvent to give low sterol, high triglyceride, microbial oil |
| US20020016317A1 (en) * | 2000-03-27 | 2002-02-07 | Schul David Allen | Sterol ester compositions |
| EP1453583B1 (en) | 2001-12-12 | 2011-08-31 | Martek Biosciences Corporation | Extraction and winterization of lipids from biomass |
| EP2295529B2 (en) * | 2002-07-11 | 2022-05-18 | Basf As | Use of a volatile environmental pollutants-decreasing working fluid for decreasing the amount of pollutants in a fat for alimentary or cosmetic use |
| EP1758991B1 (en) * | 2004-06-25 | 2013-01-16 | E.I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
| KR20070046149A (ko) * | 2004-08-24 | 2007-05-02 | 산토리 가부시키가이샤 | 디아실글리세롤의 함량을 임의로 함유한 미생물 유지의제조법 및 그 유지 |
| US7550286B2 (en) * | 2004-11-04 | 2009-06-23 | E. I. Du Pont De Nemours And Company | Docosahexaenoic acid producing strains of Yarrowia lipolytica |
| BRPI0613295A2 (pt) | 2005-07-01 | 2010-12-28 | Martek Biosciences Corp | produto oleoso contendo ácido graxo poliinsaturado e usos e produção do mesmo |
| MY139389A (en) * | 2005-07-20 | 2009-09-30 | Malaysian Palm Oil Board Mpob | Production of edible oil with high diglyceride content |
| EP2074214A2 (en) * | 2006-09-28 | 2009-07-01 | Microbia, Inc. | Production of sterols in oleaginous yeast and fungi |
| EP2561050A1 (en) * | 2010-04-22 | 2013-02-27 | E.I. Du Pont De Nemours And Company | Method for obtaining polyunsaturated fatty acid-containing compositions from microbial biomass |
| CN101851561A (zh) * | 2010-06-04 | 2010-10-06 | 江南大学 | 一种利用油脂脱臭馏出物联产生物柴油、植物甾醇和生育酚的方法 |
-
2012
- 2012-02-10 JP JP2013553603A patent/JP2014510166A/ja not_active Abandoned
- 2012-02-10 EP EP12744290.3A patent/EP2673063A1/en not_active Withdrawn
- 2012-02-10 CA CA2824776A patent/CA2824776A1/en not_active Abandoned
- 2012-02-10 US US13/370,785 patent/US9040730B2/en not_active Expired - Fee Related
- 2012-02-10 CN CN2012800078429A patent/CN103379946A/zh active Pending
- 2012-02-10 AU AU2012214285A patent/AU2012214285A1/en not_active Abandoned
- 2012-02-10 WO PCT/US2012/024687 patent/WO2012109563A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA2824776A1 (en) | 2012-08-16 |
| WO2012109563A1 (en) | 2012-08-16 |
| CN103379946A (zh) | 2013-10-30 |
| EP2673063A1 (en) | 2013-12-18 |
| JP2014510166A (ja) | 2014-04-24 |
| US9040730B2 (en) | 2015-05-26 |
| US20130046106A1 (en) | 2013-02-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1 | Application lapsed section 142(2)(a) - no request for examination in relevant period |