AU2011232434B2 - Early detection of recurrent breast cancer using metabolite profiling - Google Patents

Early detection of recurrent breast cancer using metabolite profiling Download PDF

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Publication number
AU2011232434B2
AU2011232434B2 AU2011232434A AU2011232434A AU2011232434B2 AU 2011232434 B2 AU2011232434 B2 AU 2011232434B2 AU 2011232434 A AU2011232434 A AU 2011232434A AU 2011232434 A AU2011232434 A AU 2011232434A AU 2011232434 B2 AU2011232434 B2 AU 2011232434B2
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Australia
Prior art keywords
acid
recurrence
samples
hydroxy
breast cancer
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Ceased
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AU2011232434A
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AU2011232434A1 (en
Inventor
Leiddy Alvarado
Vincent Moseti Asiago
G.A. Nagana Gowda
M. Daniel Raftery
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Purdue Research Foundation
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Purdue Research Foundation
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57415—Specifically defined cancers of breast
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/463—Flow patterns using more than one column with serial coupling of separation columns for multidimensional chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7206—Mass spectrometers interfaced to gas chromatograph
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/200833—Carbonyl, ether, aldehyde or ketone containing
    • Y10T436/201666—Carboxylic acid

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2011232434A 2010-03-23 2011-03-23 Early detection of recurrent breast cancer using metabolite profiling Ceased AU2011232434B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013231188A AU2013231188A1 (en) 2010-03-23 2013-09-24 Early detection of recurrent breast cancer using metabolite profiling

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31667910P 2010-03-23 2010-03-23
US61/316,679 2010-03-23
PCT/US2011/029681 WO2011119772A1 (en) 2010-03-23 2011-03-23 Early detection of recurrent breast cancer using metabolite profiling

Related Child Applications (1)

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AU2013231188A Division AU2013231188A1 (en) 2010-03-23 2013-09-24 Early detection of recurrent breast cancer using metabolite profiling

Publications (2)

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AU2011232434A1 AU2011232434A1 (en) 2012-11-15
AU2011232434B2 true AU2011232434B2 (en) 2013-11-21

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AU2011232434A Ceased AU2011232434B2 (en) 2010-03-23 2011-03-23 Early detection of recurrent breast cancer using metabolite profiling

Country Status (7)

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US (1) US20130023056A1 (enExample)
EP (1) EP2550533A4 (enExample)
JP (1) JP2013522652A (enExample)
AU (1) AU2011232434B2 (enExample)
CA (1) CA2793735A1 (enExample)
MX (1) MX2012010852A (enExample)
WO (1) WO2011119772A1 (enExample)

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US8653006B2 (en) 2010-09-03 2014-02-18 Purdue Research Foundation Metabolite biomarkers for the detection of esophageal cancer using NMR
US20140162903A1 (en) * 2012-10-31 2014-06-12 Purdue Research Foundation Metabolite Biomarkers For Forecasting The Outcome of Preoperative Chemotherapy For Breast Cancer Treatment
CN105451657A (zh) 2013-03-15 2016-03-30 霍罗吉克公司 用于导航断层合成堆叠的包括自动聚焦的系统和方法
EP3064940B1 (en) * 2013-10-28 2019-07-03 Salivatech Co., Ltd. Salivary biomarker for pancreatic cancer
WO2015109263A2 (en) 2014-01-17 2015-07-23 University Of Washington Biomarkers for detecting and monitoring colon cancer
BR112017004773B1 (pt) * 2014-09-10 2024-02-27 Fundação Pio Xii Hospital De Câncer De Barretos Cnpj/Mf Biomarcadores para avaliação do câncer de mama
EP3262416B1 (en) * 2015-02-27 2018-12-26 Hosmotic SRL Method for the diagnosis of endometrial carcinoma
JP6051257B2 (ja) * 2015-04-15 2016-12-27 ライオン株式会社 脂質異常症への罹患しやすさを試験する方法
CN104991010B (zh) * 2015-07-29 2017-10-13 中国药科大学 一种区分乳腺癌亚型生物标志物的组合物
WO2017213246A1 (ja) * 2016-06-10 2017-12-14 株式会社日立製作所 尿中代謝物による疾病診断法
MX2019002918A (es) 2016-09-16 2019-07-18 Dyax Corp Biomarcadores de metabolitos para enfermedades asociadas con el sistema de activacion por contacto.
WO2018183548A1 (en) 2017-03-30 2018-10-04 Hologic, Inc. System and method for hierarchical multi-level feature image synthesis and representation
US11403483B2 (en) * 2017-06-20 2022-08-02 Hologic, Inc. Dynamic self-learning medical image method and system
TWI716093B (zh) * 2019-09-02 2021-01-11 高雄醫學大學 以代謝物標誌為基礎之預測乳癌復發風險的方法
KR102283623B1 (ko) * 2019-11-06 2021-07-30 (의료)길의료재단 초음파 기법을 활용한 gc-ms 동시 분석 방법
CN112630363A (zh) * 2020-12-31 2021-04-09 四川大学华西医院 一种MXene生物响应特性代谢组学分析方法
WO2025118084A1 (en) * 2023-12-08 2025-06-12 Biomark Cancer Systems Inc. Early breast cancer detection using blood-based metabolomic profiling

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
EP0727664A3 (en) * 1995-02-15 1996-11-20 Bayer Ag Tumor markers to detect the recurrence of breast cancer
US20070221835A1 (en) * 2006-03-06 2007-09-27 Daniel Raftery Combined Spectroscopic Method for Rapid Differentiation of Biological Samples
US20090075284A1 (en) * 2006-09-19 2009-03-19 The Regents Of The University Of Michigan Metabolomic profiling of prostate cancer
BRPI0815095B1 (pt) * 2007-07-17 2021-04-13 Metabolon, Inc Método de classificação de um indivíduo de acordo com a tolerância à glicose predita em tolerância à glicose normal (ngt), tolerância à glicose de jejum prejudicada (ifg), ou tolerância à glicose prejudicada (igt), para diabetes tipo 2, método de determinação da suscetibilidade de um indivíduo a diabetes tipo 2 e método de monitoramento da progressão ou regressão do pré- diabetes em um indivíduo
US8980637B2 (en) * 2007-10-04 2015-03-17 Purdue Research Foundation Breast cancer biomarkers and identification methods using NMR and gas chromatography-mass spectrometry
CA2778226A1 (en) * 2009-10-09 2011-04-14 Carolyn Slupsky Methods for diagnosis, treatment and monitoring of patient health using metabolomics
EP2488666A4 (en) * 2009-10-13 2013-05-29 Purdue Research Foundation BIOMARKERS AND IDENTIFICATION METHOD FOR THE EARLY DETECTION AND PREDICTION OF THE REPRESENTATION OF BREAST CANCER BY NMR

Non-Patent Citations (1)

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Title
SITTER B, et. al.. NMR Biomed. 2010, 23(4):424-31. Epub 2010 Jan 25 *

Also Published As

Publication number Publication date
WO2011119772A1 (en) 2011-09-29
EP2550533A4 (en) 2014-01-08
US20130023056A1 (en) 2013-01-24
MX2012010852A (es) 2013-04-03
EP2550533A1 (en) 2013-01-30
JP2013522652A (ja) 2013-06-13
CA2793735A1 (en) 2011-09-29
AU2011232434A1 (en) 2012-11-15

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