AU2010292198A1 - PI3 kinase inhibitors and uses thereof - Google Patents

PI3 kinase inhibitors and uses thereof Download PDF

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Publication number
AU2010292198A1
AU2010292198A1 AU2010292198A AU2010292198A AU2010292198A1 AU 2010292198 A1 AU2010292198 A1 AU 2010292198A1 AU 2010292198 A AU2010292198 A AU 2010292198A AU 2010292198 A AU2010292198 A AU 2010292198A AU 2010292198 A1 AU2010292198 A1 AU 2010292198A1
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Australia
Prior art keywords
ring
nitrogen
oxygen
sulfur
independently selected
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Abandoned
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AU2010292198A
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English (en)
Inventor
Arthur F. Kluge
Kevin Kuntz
Hormoz Mazdiyasni
Deqiang Niu
Russell C. Petter
Lixin Qiao
Juswinder Singh
Zhendong Zhu
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Celgene Avilomics Research Inc
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Celgene Avilomics Research Inc
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Publication of AU2010292198A1 publication Critical patent/AU2010292198A1/en
Assigned to CELGENE AVILOMICS RESEARCH, INC. reassignment CELGENE AVILOMICS RESEARCH, INC. Alteration of Name(s) of Applicant(s) under S113 Assignors: AVILA THERAPEUTICS, INC.
Abandoned legal-status Critical Current

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Wood Science & Technology (AREA)
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  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Communicable Diseases (AREA)
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AU2010292198A 2009-09-09 2010-09-09 PI3 kinase inhibitors and uses thereof Abandoned AU2010292198A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US24094709P 2009-09-09 2009-09-09
US61/240,947 2009-09-09
US37139610P 2010-08-06 2010-08-06
US61/371,396 2010-08-06
PCT/US2010/048317 WO2011031896A2 (en) 2009-09-09 2010-09-09 Pi3 kinase inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
AU2010292198A1 true AU2010292198A1 (en) 2012-04-05

Family

ID=43733099

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010292198A Abandoned AU2010292198A1 (en) 2009-09-09 2010-09-09 PI3 kinase inhibitors and uses thereof

Country Status (16)

Country Link
US (1) US20110230476A1 (https=)
EP (1) EP2475375A4 (https=)
JP (1) JP2013504325A (https=)
KR (1) KR20120063515A (https=)
CN (1) CN102625708A (https=)
AU (1) AU2010292198A1 (https=)
BR (1) BR112012008385A2 (https=)
CA (1) CA2773848A1 (https=)
IL (1) IL218555A0 (https=)
MX (1) MX339584B (https=)
NZ (2) NZ598808A (https=)
PH (1) PH12012500491A1 (https=)
RU (1) RU2595718C2 (https=)
SG (2) SG10201405598QA (https=)
TW (2) TW201609747A (https=)
WO (1) WO2011031896A2 (https=)

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