AU2010260585B2 - Compositions and methods for treatment of Multiple Sclerosis - Google Patents

Compositions and methods for treatment of Multiple Sclerosis Download PDF

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Publication number
AU2010260585B2
AU2010260585B2 AU2010260585A AU2010260585A AU2010260585B2 AU 2010260585 B2 AU2010260585 B2 AU 2010260585B2 AU 2010260585 A AU2010260585 A AU 2010260585A AU 2010260585 A AU2010260585 A AU 2010260585A AU 2010260585 B2 AU2010260585 B2 AU 2010260585B2
Authority
AU
Australia
Prior art keywords
multiple sclerosis
treatment
microparticle
mis416
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2010260585A
Other languages
English (en)
Other versions
AU2010260585A8 (en
AU2010260585A1 (en
Inventor
Frank B. Gelder
Gillian Alison Webster
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innate Immunotherapeutics Ltd
Original Assignee
Innate Immunotherapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innate Immunotherapeutics Ltd filed Critical Innate Immunotherapeutics Ltd
Publication of AU2010260585A1 publication Critical patent/AU2010260585A1/en
Publication of AU2010260585A8 publication Critical patent/AU2010260585A8/en
Application granted granted Critical
Publication of AU2010260585B2 publication Critical patent/AU2010260585B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Photographic Developing Apparatuses (AREA)
AU2010260585A 2009-06-16 2010-06-16 Compositions and methods for treatment of Multiple Sclerosis Ceased AU2010260585B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NZ577731A NZ577731A (en) 2009-06-16 2009-06-16 Compositions and methods for treatment of multiple sclerosis
NZ577731 2009-06-16
PCT/NZ2010/000112 WO2010147484A1 (en) 2009-06-16 2010-06-16 Compositions and methods for treatment of multiple sclerosis

Publications (3)

Publication Number Publication Date
AU2010260585A1 AU2010260585A1 (en) 2012-01-19
AU2010260585A8 AU2010260585A8 (en) 2012-06-14
AU2010260585B2 true AU2010260585B2 (en) 2013-02-21

Family

ID=42646236

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010260585A Ceased AU2010260585B2 (en) 2009-06-16 2010-06-16 Compositions and methods for treatment of Multiple Sclerosis

Country Status (20)

Country Link
US (1) US8389479B2 (enExample)
EP (1) EP2442832B1 (enExample)
JP (1) JP5646617B2 (enExample)
CN (1) CN102458476B (enExample)
AU (1) AU2010260585B2 (enExample)
BR (1) BRPI1009606A2 (enExample)
CA (1) CA2688766C (enExample)
CY (1) CY1115714T1 (enExample)
DK (1) DK2442832T3 (enExample)
ES (1) ES2521565T3 (enExample)
HR (1) HRP20141035T1 (enExample)
IL (1) IL216993A (enExample)
IN (1) IN2012DN00167A (enExample)
MX (1) MX2011013661A (enExample)
NZ (1) NZ577731A (enExample)
PL (1) PL2442832T3 (enExample)
PT (1) PT2442832E (enExample)
SI (1) SI2442832T1 (enExample)
SM (1) SMT201400165B (enExample)
WO (1) WO2010147484A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2719252C (en) * 2008-04-01 2016-01-19 Innate Therapeutics Limited Anti-infective agents comprising muramyl dipeptide microparticles and uses thereof
JP5847188B2 (ja) 2010-10-25 2016-01-20 バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. sVCAMおよび/またはsMAdCAMレベルの差を関連付けることにより、アルファ−4インテグリン活性の差を決定するための方法
UY35790A (es) * 2013-10-21 2015-05-29 Teva Pharma Marcadores genéticos que predicen la respuesta al acetato de glatiramer
CA2926507A1 (en) * 2015-10-06 2017-04-06 Innate Immunotherapeutics Limited Compositions and methods for protection and/or repair of the nervous system
WO2017059486A1 (en) * 2015-10-06 2017-04-13 Innate Immunotherapeutics Limited Compositions and methods for the treatment of epilepsy
WO2017070731A1 (en) * 2015-10-28 2017-05-04 Innate Immunotherapeutics Limited Compositions and methods for the treatment of alzheimer's disease
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
HRP20250396T1 (hr) 2016-08-31 2025-05-23 Mapi Pharma Ltd. Depo sustavi koji sadrže glatiramer acetat
AU2018242998B2 (en) 2017-03-26 2023-11-02 Mapi Pharma Ltd. Glatiramer depot systems for treating progressive forms of multiple sclerosis
CA3099946A1 (en) * 2018-05-18 2019-11-21 Universite Laval Use of nod2 agonist for the treatment, prophylaxis and/or delay of the onset of multiple sclerosis and alzheimer's disease
US12109271B2 (en) 2018-07-03 2024-10-08 University Of Florida Research Foundation, Incorporated Microparticle systems and their use for the treatment of multiple sclerosis
US20230190570A1 (en) * 2020-06-22 2023-06-22 Otivio As Methods for treating spasticity using anti-spasmodic compositions and negative pressure therapy

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6335017B1 (en) * 1996-10-10 2002-01-01 Probe International Inc. Compositions and methods for treating viral infections
WO2008150182A1 (en) * 2007-06-05 2008-12-11 Innate Therapeutics Limited Compositions and methods for treatment of anthrax
WO2008150181A1 (en) * 2007-06-05 2008-12-11 Innate Therapeutics Limited Compositions and methods for treating anthrax exposure associated conditions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0512921A (pt) * 2004-07-01 2008-04-22 Den Kgl Veterinaer Og Landboho processo para tratamento e profilaxia de ms
US8603978B2 (en) * 2006-12-01 2013-12-10 The United States of America, as represented by the Secretary, Department of Health and Humand Services Use of muramyl dipeptide (MDP) for treating inflammation
JP2008251608A (ja) 2007-03-29 2008-10-16 Casio Comput Co Ltd 半導体装置およびその製造方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6335017B1 (en) * 1996-10-10 2002-01-01 Probe International Inc. Compositions and methods for treating viral infections
WO2008150182A1 (en) * 2007-06-05 2008-12-11 Innate Therapeutics Limited Compositions and methods for treatment of anthrax
WO2008150181A1 (en) * 2007-06-05 2008-12-11 Innate Therapeutics Limited Compositions and methods for treating anthrax exposure associated conditions

Also Published As

Publication number Publication date
BRPI1009606A2 (pt) 2016-10-11
PL2442832T3 (pl) 2015-01-30
EP2442832A1 (en) 2012-04-25
IL216993A (en) 2016-03-31
JP2012530132A (ja) 2012-11-29
DK2442832T3 (da) 2014-11-10
JP5646617B2 (ja) 2014-12-24
IN2012DN00167A (enExample) 2015-04-17
AU2010260585A8 (en) 2012-06-14
US20100317589A1 (en) 2010-12-16
CN102458476B (zh) 2014-08-20
ES2521565T3 (es) 2014-11-12
HK1167101A1 (en) 2013-02-01
NZ577731A (en) 2010-08-27
EP2442832B1 (en) 2014-08-06
IL216993A0 (en) 2012-02-29
SI2442832T1 (sl) 2014-12-31
PT2442832E (pt) 2014-11-11
WO2010147484A8 (en) 2012-07-19
EP2442832A4 (en) 2013-07-03
MX2011013661A (es) 2012-05-22
CY1115714T1 (el) 2017-01-25
HRP20141035T1 (hr) 2014-12-19
WO2010147484A1 (en) 2010-12-23
SMT201400165B (it) 2015-01-15
CA2688766C (en) 2015-06-30
US8389479B2 (en) 2013-03-05
CN102458476A (zh) 2012-05-16
CA2688766A1 (en) 2010-12-16
AU2010260585A1 (en) 2012-01-19

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Legal Events

Date Code Title Description
TH Corrigenda

Free format text: IN VOL 26, NO 2, PAGE(S) 255 UNDER THE HEADING PCT APPLICATIONS THAT HAVE ENTERED THE NATIONAL PHASE - NAME INDEX UNDER THE NAME INNATE IMMUNOTHERAPEUTICS LIMITED, APPLICATION NO. 2010260585, UNDER INID (22) CORRECT THE FILING DATE TO READ 16 JUNE 2010

TH Corrigenda

Free format text: IN VOL 26 , NO 2 , PAGE(S) 255 UNDER THE HEADING PCT APPLICATIONS THAT HAVE ENTERED THE NATIONAL PHASE - NAME INDEX UNDER THE NAME INNATE IMMUNOTHERAPEUTICS LIMITED, APPLICATION NO. 2010260585, UNDER INID (31) CORRECT THE NUMBER TO READ 577731

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired