AU2009246166B2 - Anti-PSGL-1 antibodies and methods of identification and use - Google Patents
Anti-PSGL-1 antibodies and methods of identification and use Download PDFInfo
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- AU2009246166B2 AU2009246166B2 AU2009246166A AU2009246166A AU2009246166B2 AU 2009246166 B2 AU2009246166 B2 AU 2009246166B2 AU 2009246166 A AU2009246166 A AU 2009246166A AU 2009246166 A AU2009246166 A AU 2009246166A AU 2009246166 B2 AU2009246166 B2 AU 2009246166B2
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| PCT/US2009/044188 WO2009140623A2 (en) | 2008-05-15 | 2009-05-15 | Anti-psgl-1 antibodies and methods of identification and use |
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| US8945565B2 (en) | 2006-12-01 | 2015-02-03 | Selexys Pharmaceuticals Corporation | Methods of treating inflammatory or thrombotic conditions with anti-P-selectin antibodies |
| PT2662091T (pt) | 2006-12-01 | 2018-12-03 | Novartis Ag | Anticorpos anti-p-selectina e métodos para os utilizar no tratamento de doenças inflamatórias |
| WO2012088265A1 (en) * | 2010-12-21 | 2012-06-28 | Selexys Pharmaceuticals Corporation | Anti-p-selectin antibodies and methods of their use and identification |
| BR112013031892A2 (pt) * | 2011-06-13 | 2016-11-22 | Abgenomics Cooperatief Ua | anticorpos anti-psgl-1 e seu uso |
| JP6236255B2 (ja) * | 2012-08-31 | 2017-11-22 | 旭化成メディカル株式会社 | 基材及びデバイス |
| WO2018132476A1 (en) | 2017-01-11 | 2018-07-19 | Bristol-Myers Squibb Company | Psgl-1 antagonists and uses thereof |
| KR20240151866A (ko) | 2017-03-14 | 2024-10-18 | 파이브 프라임 테라퓨틱스, 인크. | 산성 pH에서 VISTA에 결합하는 항체 |
| EP3619299A1 (en) * | 2017-05-03 | 2020-03-11 | BioMarin Pharmaceutical Inc. | Improved lentiviruses for transduction of hematopoietic stem cells. |
| JP7510879B2 (ja) | 2018-03-21 | 2024-07-04 | ファイヴ プライム セラピューティクス インク | 酸性ｐＨでＶＩＳＴＡに結合する抗体 |
| TW202023629A (zh) * | 2018-06-29 | 2020-07-01 | 美商維西歐製藥公司 | 用於調節單核球及巨噬細胞發炎表型之組合物及方法以及其免疫療法用途 |
| KR20210031722A (ko) | 2018-07-11 | 2021-03-22 | 파이브 프라임 테라퓨틱스, 인크. | 산성 pH에서 VISTA에 결합하는 항체 |
| MX2021000786A (es) | 2018-07-20 | 2021-06-15 | Pf Medicament | Receptor para supresor de ig del dominio v de activación de células t (vista). |
| WO2020247371A1 (en) * | 2019-06-04 | 2020-12-10 | Verseau Therapeutics, Inc. | Anti-psgl-1 compositions and methods for modulating myeloid cell inflammatory phenotypes and uses thereof |
| KR102242285B1 (ko) * | 2019-10-02 | 2021-04-20 | 코아스템(주) | 중간엽줄기세포의 전신홍반루푸스 치료효과 예측용 바이오마커 조성물 |
| CN113322223B (zh) * | 2021-06-03 | 2023-09-12 | 重庆市畜牧科学院 | 富硒酵母基因工程菌及其表面展示系统及其构建方法 |
| CN113667015B (zh) * | 2021-08-20 | 2022-10-11 | 北京康特泊瑞生物医药科技股份公司 | 靶向psgl-1蛋白的抗体及其用途 |
| KR20250094658A (ko) * | 2022-09-13 | 2025-06-25 | 테더렉스 파마슈티컬스 코포레이션 | 항체, 조성물 및 치료 방법 |
| WO2025191538A1 (en) * | 2024-03-14 | 2025-09-18 | Tetherex Pharmaceuticals Corporation | Pharmaceutical compositions and methods of treatment |
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| US20070160601A1 (en) * | 2005-12-09 | 2007-07-12 | Angela Widom | Neutralizing antibodies against primate psgl-1 and uses therefor |
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| JPS5896026A (ja) | 1981-10-30 | 1983-06-07 | Nippon Chemiphar Co Ltd | 新規ウロキナ−ゼ誘導体およびその製造法ならびにそれを含有する血栓溶解剤 |
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| US4766106A (en) | 1985-06-26 | 1988-08-23 | Cetus Corporation | Solubilization of proteins for pharmaceutical compositions using polymer conjugation |
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| US5667988A (en) * | 1992-01-27 | 1997-09-16 | The Scripps Research Institute | Methods for producing antibody libraries using universal or randomized immunoglobulin light chains |
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| US20040002450A1 (en) * | 2000-12-29 | 2004-01-01 | Janette Lazarovits | Y17 - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof |
| US20040001839A1 (en) * | 2000-12-29 | 2004-01-01 | Avigdor Levanon | Multimers - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof |
| US7744888B2 (en) * | 2001-08-03 | 2010-06-29 | Abgenomics Cooperatief U.A. | Methods of modulating T cell or natural killer cell activity with anti-P-selectin glycoprotein ligand 1 antibodies |
| WO2003088980A1 (en) * | 2002-04-18 | 2003-10-30 | Embury Stephen H | Method and composition for preventing pain in sickle cell patients |
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| WO2007143711A2 (en) * | 2006-06-07 | 2007-12-13 | Wisconsin Alumni Research Foundation | Blood-brain barrier targeting antibodies |
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Patent Citations (1)
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|---|---|---|---|---|
| US20070160601A1 (en) * | 2005-12-09 | 2007-07-12 | Angela Widom | Neutralizing antibodies against primate psgl-1 and uses therefor |
Non-Patent Citations (1)
| Title |
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| HIRATA et al. Human P-selectin Glycoprotein Ligand-1 (PSGL-1) Interacts with the Skin- 14-20 associated Chemokine CCL27 via Sulfated Tyrosines at the PSGL-1 Amino Terminus. J Biol. Chem. 2004, 279(50):51775-51782. * |
Also Published As
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| EP3388527A1 (en) | 2018-10-17 |
| WO2009140623A2 (en) | 2009-11-19 |
| EP2291536A2 (en) | 2011-03-09 |
| CA2724415A1 (en) | 2009-11-19 |
| US20110081666A1 (en) | 2011-04-07 |
| WO2009140623A3 (en) | 2010-01-28 |
| JP2011524858A (ja) | 2011-09-08 |
| CA2724415C (en) | 2016-09-13 |
| EP2291536A4 (en) | 2013-02-27 |
| US20090285812A1 (en) | 2009-11-19 |
| AU2009246166A1 (en) | 2009-11-19 |
| US7833530B2 (en) | 2010-11-16 |
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