AU2009214590A1 - Improved methods for producing specific binding pairs - Google Patents

Improved methods for producing specific binding pairs Download PDF

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Publication number
AU2009214590A1
AU2009214590A1 AU2009214590A AU2009214590A AU2009214590A1 AU 2009214590 A1 AU2009214590 A1 AU 2009214590A1 AU 2009214590 A AU2009214590 A AU 2009214590A AU 2009214590 A AU2009214590 A AU 2009214590A AU 2009214590 A1 AU2009214590 A1 AU 2009214590A1
Authority
AU
Australia
Prior art keywords
vectors
population
phage
polypeptide chains
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2009214590A
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English (en)
Inventor
Robert C. Ladner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dyax Corp
Original Assignee
Dyax Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyax Corp filed Critical Dyax Corp
Publication of AU2009214590A1 publication Critical patent/AU2009214590A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
AU2009214590A 2008-02-13 2009-02-13 Improved methods for producing specific binding pairs Abandoned AU2009214590A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2826508P 2008-02-13 2008-02-13
US61/028,265 2008-02-13
US4393808P 2008-04-10 2008-04-10
US61/043,938 2008-04-10
PCT/US2009/034016 WO2009102927A1 (en) 2008-02-13 2009-02-13 Improved methods for producing specific binding pairs

Publications (1)

Publication Number Publication Date
AU2009214590A1 true AU2009214590A1 (en) 2009-08-20

Family

ID=40957275

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009214590A Abandoned AU2009214590A1 (en) 2008-02-13 2009-02-13 Improved methods for producing specific binding pairs

Country Status (6)

Country Link
US (1) US20090215119A1 (ja)
EP (1) EP2245153A4 (ja)
JP (1) JP2011511647A (ja)
AU (1) AU2009214590A1 (ja)
CA (1) CA2715297A1 (ja)
WO (1) WO2009102927A1 (ja)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
US8288322B2 (en) 2000-04-17 2012-10-16 Dyax Corp. Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
DK1531791T3 (da) 2002-06-07 2010-11-01 Dyax Corp Forebyggelse og begrænsning af iskæmi
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
ES2395014T3 (es) 2002-08-28 2013-02-07 Dyax Corp. Métodos para conservar órganos y tejidos
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US9873957B2 (en) 2008-03-13 2018-01-23 Dyax Corp. Libraries of genetic packages comprising novel HC CDR3 designs
WO2009132287A2 (en) 2008-04-24 2009-10-29 Dyax Corp. Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs
WO2010080833A1 (en) 2009-01-06 2010-07-15 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
RS57870B1 (sr) 2010-01-06 2018-12-31 Dyax Corp Proteini koji vezuju kalikrein plazme
KR102107695B1 (ko) 2011-01-06 2020-05-07 다이액스 코포레이션 혈장 칼리크레인 결합 단백질
WO2012122571A1 (en) 2011-03-10 2012-09-13 Gen-Probe Incorporated Methods and compositions for the selection and optimization of oligonucleotide tag sequences
BR112016022318A2 (pt) 2014-03-27 2017-10-31 Dyax Corp método, composição farmacêutica para uso no tratamento de doenças de retina e uso de um anticorpo
KR20180069839A (ko) * 2015-10-08 2018-06-25 자임워크스 인코포레이티드 카파 및 람다 경사슬을 포함하는 항원-결합 폴리펩티드 구조체 및 이의 용도
BR112018011622A2 (pt) 2015-12-11 2018-11-27 Dyax Corp método para tratar ataque de angioedema hereditário (hae) ou reduzir a taxa de ataque de hae
BR112022007219A2 (pt) * 2019-10-17 2022-07-05 Univ Minnesota Sequências de fragmento de anticorpo clec12a e métodos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5780225A (en) * 1990-01-12 1998-07-14 Stratagene Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
US5427908A (en) * 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) * 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5858657A (en) * 1992-05-15 1999-01-12 Medical Research Council Methods for producing members of specific binding pairs
US5962255A (en) * 1992-03-24 1999-10-05 Cambridge Antibody Technology Limited Methods for producing recombinant vectors

Also Published As

Publication number Publication date
JP2011511647A (ja) 2011-04-14
EP2245153A4 (en) 2011-06-22
US20090215119A1 (en) 2009-08-27
EP2245153A1 (en) 2010-11-03
CA2715297A1 (en) 2009-08-20
WO2009102927A1 (en) 2009-08-20

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application