AU2008211854C1 - Novel macromolecule transduction domains and methods for identification and uses thereof - Google Patents
Novel macromolecule transduction domains and methods for identification and uses thereof Download PDFInfo
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- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
- A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
- A61K48/0041—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being polymeric
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K7/04—Linear peptides containing only normal peptide links
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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Landscapes
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| US88706007P | 2007-01-29 | 2007-01-29 | |
| US60/887,060 | 2007-01-29 | ||
| PCT/KR2008/000525 WO2008093982A1 (en) | 2007-01-29 | 2008-01-29 | Novel macromolecule transduction domains and methods for identification and uses thereof |
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| AU2008211854A1 AU2008211854A1 (en) | 2008-08-07 |
| AU2008211854B2 AU2008211854B2 (en) | 2012-08-16 |
| AU2008211854C1 true AU2008211854C1 (en) | 2014-01-23 |
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| US (2) | US8629097B2 (https=) |
| EP (2) | EP2837636B1 (https=) |
| JP (3) | JP5518488B2 (https=) |
| KR (18) | KR20090103957A (https=) |
| CN (1) | CN101616928B (https=) |
| AU (1) | AU2008211854C1 (https=) |
| CA (1) | CA2676797C (https=) |
| WO (1) | WO2008093982A1 (https=) |
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| CA2822302A1 (en) | 2006-02-13 | 2007-08-23 | Alethia Biotherapeutics Inc. | Methods of impairing osteoclast differentiation |
| US8168181B2 (en) | 2006-02-13 | 2012-05-01 | Alethia Biotherapeutics, Inc. | Methods of impairing osteoclast differentiation using antibodies that bind siglec-15 |
| US8158415B2 (en) | 2007-02-27 | 2012-04-17 | Procell Therapeutics Inc. | Combined use of cell permeable Nanog and Oct4 for increasing self-renewal and suppressing differentiation of stem cells |
| KR100887266B1 (ko) * | 2007-09-04 | 2009-03-06 | 주식회사 프로셀제약 | 세포투과성 ｐ１８ 재조합 단백질, 이를 코딩하는폴리뉴클레오티드 및 이를 유효성분으로 함유하는 항암조성물 |
| EP2185707B1 (en) * | 2007-09-04 | 2013-07-03 | Procell Therapeutics Inc. | Cell permeable nm23 recombinant proteins, polynucleotides encoding the same, and anti-metastatic composition comprising the same |
| KR20100093523A (ko) * | 2007-11-06 | 2010-08-25 | 주식회사 프로셀제약 | 세포투과성 ｒｕｎｘ３ 재조합 단백질, 이를 코딩하는 폴리뉴클레오티드 및 이를 유효성분으로 함유하는 항암 조성물 |
| EP2270055A4 (en) * | 2008-04-04 | 2011-06-29 | Procell Therapeutics Inc | CELLPERMEABLE RECOMBINANT ENDOSTATINE PROTEIN, POLYNUCLEOTIDE FOR ITS CODING AND ANTICIPATED PREPARATION WITH THE PROTEIN AS AN ACTIVE SUBSTANCE |
| EP2407488A4 (en) * | 2009-03-12 | 2013-03-13 | Procell Therapeutics Inc | DETERMINATION OF INDUCED PLURIPOTENT STEM CELLS BASED ON A CELL PERMEABLIC REPOGRAMMING TRANSCRIPTION FACTOR FOR PERSONALIZED STEM CELL THERAPY |
| AU2010306940A1 (en) | 2009-10-12 | 2012-06-07 | Smith, Larry | Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro |
| TW201302800A (zh) * | 2011-06-10 | 2013-01-16 | 腫瘤療法 科學股份有限公司 | Ｓｅｍａ５ｂ胜肽及含其之疫苗 |
| EP2559441B1 (en) | 2011-08-16 | 2021-07-21 | Samsung Electronics Co., Ltd. | Protein complex for intracellular delivery and uses thereof |
| ES2621337T3 (es) * | 2011-11-23 | 2017-07-03 | Procell Therapeutics Inc. | Desarrollo de nuevo dominio de transducción macromolecular con mejor permeabilidad celular y método de uso del mismo |
| KR101393397B1 (ko) * | 2011-11-23 | 2014-05-14 | 주식회사 프로셀제약 | 세포내 분자 전송 펩티드를 이용한 피부 생리 활성 분자의 경피 전달시스템 |
| WO2013169060A1 (ko) | 2012-05-11 | 2013-11-14 | 주식회사 카엘젬백스 | 패혈증 예방 또는 치료용 조성물 |
| ES2691070T3 (es) | 2012-05-11 | 2018-11-23 | Kael-Gemvax Co.,Ltd | Péptidos antiinflamatorios y composición que comprende los mismos |
| US9994829B2 (en) | 2012-07-02 | 2018-06-12 | Iprogen Biotech, Inc. | Intracellular protein delivery |
| ES2981865T3 (es) | 2012-07-11 | 2024-10-10 | Gemvax & Kael Co Ltd | Conjugado que comprende un péptido de penetración celular y composiciones que comprenden el mismo |
| HK1210192A1 (en) | 2012-07-19 | 2016-04-15 | Alethia Biotherapeutics Inc. | Anti-siglec-15 antibodies |
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