AU2007243287B2 - Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith - Google Patents

Info

Publication number

AU2007243287B2

AU2007243287B2 AU2007243287A AU2007243287A AU2007243287B2 AU 2007243287 B2 AU2007243287 B2 AU 2007243287B2 AU 2007243287 A AU2007243287 A AU 2007243287A AU 2007243287 A AU2007243287 A AU 2007243287A AU 2007243287 B2 AU2007243287 B2 AU 2007243287B2

Authority

AU

Australia

Prior art keywords

substituted

unsubstituted

diabetes

compound

kinase

Prior art date

2006-04-26

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Ceased

Links

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• 238000000034 method Methods 0.000 title claims abstract description 252
• 238000011282 treatment Methods 0.000 title claims description 30
• 239000000203 mixture Chemical class 0.000 title abstract description 80
• 150000005018 aminopurines Chemical class 0.000 title abstract description 7
• 125000003106 haloaryl group Chemical group 0.000 title 1
• -1 Aminopurine Compounds Chemical class 0.000 claims abstract description 274
• 150000001875 compounds Chemical class 0.000 claims abstract description 272
• 125000000217 alkyl group Chemical group 0.000 claims description 66
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• 125000003118 aryl group Chemical group 0.000 claims description 54
• 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 49
• 150000003839 salts Chemical class 0.000 claims description 32
• 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 25
• 229910052736 halogen Inorganic materials 0.000 claims description 24
• 125000003545 alkoxy group Chemical group 0.000 claims description 23
• 125000004183 alkoxy alkyl group Chemical group 0.000 claims description 21
• 125000002768 hydroxyalkyl group Chemical group 0.000 claims description 21
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• 125000004093 cyano group Chemical group *C#N 0.000 claims description 18
• 125000002883 imidazolyl group Chemical group 0.000 claims description 18
• 125000003831 tetrazolyl group Chemical group 0.000 claims description 18
• 125000001425 triazolyl group Chemical group 0.000 claims description 18
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• 125000003282 alkyl amino group Chemical group 0.000 claims description 17
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