AU2005334514B2 - Particles for treatment of pulmonary infection - Google Patents

Particles for treatment of pulmonary infection Download PDF

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Publication number
AU2005334514B2
AU2005334514B2 AU2005334514A AU2005334514A AU2005334514B2 AU 2005334514 B2 AU2005334514 B2 AU 2005334514B2 AU 2005334514 A AU2005334514 A AU 2005334514A AU 2005334514 A AU2005334514 A AU 2005334514A AU 2005334514 B2 AU2005334514 B2 AU 2005334514B2
Authority
AU
Australia
Prior art keywords
formulation
capreomycin
treatment
particles
microparticles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005334514A
Other languages
English (en)
Other versions
AU2005334514A1 (en
Inventor
David A. Edwards
Jennifer Fiegel
Jean Sung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard University
Original Assignee
Harvard University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard University filed Critical Harvard University
Publication of AU2005334514A1 publication Critical patent/AU2005334514A1/en
Application granted granted Critical
Publication of AU2005334514B2 publication Critical patent/AU2005334514B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Biophysics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2005334514A 2004-10-29 2005-10-19 Particles for treatment of pulmonary infection Ceased AU2005334514B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62373804P 2004-10-29 2004-10-29
US60/623,738 2004-10-29
PCT/US2005/037484 WO2007011396A2 (en) 2004-10-29 2005-10-19 Particles for treatment of pulmonary infection

Publications (2)

Publication Number Publication Date
AU2005334514A1 AU2005334514A1 (en) 2007-01-25
AU2005334514B2 true AU2005334514B2 (en) 2009-11-26

Family

ID=37667331

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005334514A Ceased AU2005334514B2 (en) 2004-10-29 2005-10-19 Particles for treatment of pulmonary infection

Country Status (11)

Country Link
US (1) US8846607B2 (cg-RX-API-DMAC7.html)
EP (1) EP1809252A2 (cg-RX-API-DMAC7.html)
JP (1) JP2008518007A (cg-RX-API-DMAC7.html)
CN (1) CN101090711A (cg-RX-API-DMAC7.html)
AU (1) AU2005334514B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0517374A (cg-RX-API-DMAC7.html)
CA (1) CA2585859C (cg-RX-API-DMAC7.html)
IL (1) IL182785A0 (cg-RX-API-DMAC7.html)
RU (1) RU2007119721A (cg-RX-API-DMAC7.html)
WO (1) WO2007011396A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200703452B (cg-RX-API-DMAC7.html)

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US11446374B2 (en) 2008-12-09 2022-09-20 Novavax, Inc. Modified RSV F proteins and methods of their use
EP3718566B1 (en) 2008-12-09 2024-06-12 Novavax, Inc. Modified rsv f proteins and methods of their use
RU2399385C1 (ru) * 2009-03-10 2010-09-20 Общество с ограниченной ответственностью "Научно-производственная фирма "НОРД" Способ профилактической обработки животных и птиц
EP2421518A2 (en) * 2009-04-24 2012-02-29 Schering Corporation Agglomerate formulations including active pharmaceutical agents with targeted particle sizes
NZ596610A (en) * 2009-05-27 2014-04-30 Samyang Biopharmaceuticals A poorly soluble drug containing microsphere with improved bioavailability and method of preparing the same
CN102573886A (zh) * 2009-09-17 2012-07-11 相互制药公司 用抗病毒剂治疗哮喘的方法
CN102225058A (zh) * 2011-06-22 2011-10-26 中国药科大学 磷酸奥司他韦吸入粉雾剂及其制备方法
KR20140147891A (ko) * 2012-04-13 2014-12-30 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 응집체 입자
RU2562550C2 (ru) * 2013-12-19 2015-09-10 Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский институт бруцеллеза и туберкулеза животных" (ФГБНУ ВНИИБТЖ) Способ специфической профилактики туберкулеза
KR102758377B1 (ko) 2015-09-03 2025-01-23 노바백스, 인코포레이티드 개선된 안정성 및 면역원성을 갖는 백신 조성물
WO2018226949A1 (en) 2017-06-08 2018-12-13 Pai Life Sciences Inc. Cpzen compositions and uses
CN109260180A (zh) * 2017-07-17 2019-01-25 北京盈科瑞创新药物研究有限公司 一种盐酸莫西沙星雾化吸入用溶液制剂及其制备方法
JP7317796B2 (ja) 2017-07-24 2023-07-31 ノババックス，インコーポレイテッド 呼吸器疾患を治療するための方法および組成物
IL305911B2 (en) 2018-03-19 2025-01-01 Novavax Inc Multifunctional nanoparticle influenza vaccines
US20210338671A1 (en) * 2018-07-24 2021-11-04 Board Of Regents, The University Of Texas System Compositions of surface-modified therapeutically active particles by ultra-rapid freezing
EP4142702A1 (en) * 2020-05-01 2023-03-08 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. E protein channel blockers and orf3 inhibitors as anti-covid-19 agents
US20230338365A1 (en) * 2020-05-14 2023-10-26 Kowa Company, Ltd. Novel inhalant
JPWO2022044582A1 (cg-RX-API-DMAC7.html) * 2020-08-28 2022-03-03
CA3206024A1 (en) * 2021-02-01 2022-08-04 The Global Alliance For Tb Drug Development, Inc. Pretomanid amorphous form
JP2024049405A (ja) * 2021-02-22 2024-04-10 興和株式会社 新規吸入剤
CN113907360A (zh) * 2021-07-30 2022-01-11 湖南达侑科技有限公司 植物甾醇磷脂组合物及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003043586A2 (en) * 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Compositions for sustained action product delivery

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US4069819A (en) 1973-04-13 1978-01-24 Societa Farmaceutici S.P.A. Inhalation device
US5192528A (en) * 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
IT1228459B (it) 1989-02-23 1991-06-19 Phidea S R L Inalatore con svuotamento regolare e completo della capsula.
IS1796B (is) 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
WO1995022963A1 (en) * 1994-02-28 1995-08-31 Medinova Medical Consulting Gmbh Drug targeting system, method for preparing same and its use
CZ295827B6 (cs) * 1994-03-07 2005-11-16 Nektar Therapeutics Způsob aerosolizace dávky inzulinu, inzulinový přípravek a jeho použití
US5814617A (en) * 1994-10-07 1998-09-29 The United States Of America As Represented By The Secretary Of The Navy Protective 17 KDA malaria hepatic and erythrocytic stage immunogen and gene
ATE217792T1 (de) 1995-07-05 2002-06-15 Europ Economic Community Biokompatibele und biodegradierbare nanokapseln zur absorption und verabreichung von proteinischen arzneimitteln
US6143211A (en) 1995-07-21 2000-11-07 Brown University Foundation Process for preparing microparticles through phase inversion phenomena
US5855913A (en) * 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
US20020052310A1 (en) 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
US5985309A (en) 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US6517860B1 (en) * 1996-12-31 2003-02-11 Quadrant Holdings Cambridge, Ltd. Methods and compositions for improved bioavailability of bioactive agents for mucosal delivery
US20030059471A1 (en) * 1997-12-15 2003-03-27 Compton Bruce Jon Oral delivery formulation
US7521068B2 (en) 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
US6586008B1 (en) * 1999-08-25 2003-07-01 Advanced Inhalation Research, Inc. Use of simple amino acids to form porous particles during spray drying
DE60025019T2 (de) * 1999-10-29 2006-08-24 Nektar Therapeutics, San Carlos Trockenpulverzusammensetzungen mit verbesserter dispersivität
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WO2004024213A2 (en) * 2002-09-12 2004-03-25 The Government Of The United States, As Represented By The Secretary Of The Department Of Health And Human Services Aerosolized capreomycin for inhibition of pulmonary tuberculosis
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Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2003043586A2 (en) * 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Compositions for sustained action product delivery

Also Published As

Publication number Publication date
CA2585859C (en) 2012-03-06
US20080213373A1 (en) 2008-09-04
BRPI0517374A (pt) 2008-10-07
EP1809252A2 (en) 2007-07-25
ZA200703452B (en) 2008-06-25
AU2005334514A1 (en) 2007-01-25
CN101090711A (zh) 2007-12-19
RU2007119721A (ru) 2008-12-10
US8846607B2 (en) 2014-09-30
IL182785A0 (en) 2007-09-20
CA2585859A1 (en) 2007-01-25
WO2007011396A3 (en) 2007-05-03
JP2008518007A (ja) 2008-05-29
WO2007011396A2 (en) 2007-01-25

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired