AU2005238445B2 - Compounds for enzyme inhibition - Google Patents
Compounds for enzyme inhibition Download PDFInfo
- Publication number
- AU2005238445B2 AU2005238445B2 AU2005238445A AU2005238445A AU2005238445B2 AU 2005238445 B2 AU2005238445 B2 AU 2005238445B2 AU 2005238445 A AU2005238445 A AU 2005238445A AU 2005238445 A AU2005238445 A AU 2005238445A AU 2005238445 B2 AU2005238445 B2 AU 2005238445B2
- Authority
- AU
- Australia
- Prior art keywords
- compound
- alkyl
- treating
- hydrogen
- administering
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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Landscapes
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| US62057304P | 2004-10-20 | 2004-10-20 | |
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| PCT/US2005/012740 WO2005105827A2 (en) | 2004-04-15 | 2005-04-14 | Compounds for proteasome enzyme inhibition |
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| AU2012203602B2 (en) * | 2004-04-15 | 2015-08-27 | Onyx Therapeutics, Inc. | Compounds for proteasome enzyme inhibition |
| JP5616569B2 (ja) | 2004-04-15 | 2014-10-29 | オニキス セラピューティクス， インク．Ｏｎｙｘ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | 酵素阻害のための化合物 |
| US8198270B2 (en) | 2004-04-15 | 2012-06-12 | Onyx Therapeutics, Inc. | Compounds for proteasome enzyme inhibition |
| US7232818B2 (en) * | 2004-04-15 | 2007-06-19 | Proteolix, Inc. | Compounds for enzyme inhibition |
| EP1758921A2 (en) | 2004-05-10 | 2007-03-07 | Proteolix, Inc. | Compounds for proteasome enzyme inhibition |
| JP4990155B2 (ja) | 2004-12-07 | 2012-08-01 | プロテオリックス， インコーポレイテッド | プロテアソームを阻害するための組成物 |
| ES2628620T3 (es) | 2005-11-09 | 2017-08-03 | Onyx Therapeutics, Inc. | Compuesto para inhibición de enzimas |
| PT2041158E (pt) | 2006-06-19 | 2013-07-17 | Onyx Therapeutics Inc | Péptido epoxicetonas para inibição de proteassoma |
| MY173938A (en) | 2007-10-04 | 2020-02-27 | Onyx Therapeutics Inc | Crystalline peptide epoxy ketone protease inhibitors and the synthesis of amino acid keto-epoxides |
| AU2009308516B2 (en) | 2008-10-21 | 2016-08-25 | Onyx Therapeutics, Inc. | Combination therapy with peptide epoxyketones |
| AU2010225426B2 (en) | 2009-03-16 | 2015-09-03 | The Governing Council Of The University Of Toronto | Cyclic amino acid molecules and methods of preparing the same |
| AR075899A1 (es) | 2009-03-20 | 2011-05-04 | Onyx Therapeutics Inc | Tripeptidos epoxicetonas cristalinos inhibidores de proteasa |
| GB0914883D0 (en) | 2009-08-26 | 2009-09-30 | Univ Belfast | Compound |
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| US9359398B2 (en) | 2010-03-01 | 2016-06-07 | Onyx Therapeutics, Inc. | Compounds for immunoproteasome inhibition |
| NZ602872A (en) | 2010-04-07 | 2014-05-30 | Onyx Therapeutics Inc | Crystalline peptide epoxyketone immunoproteasome inhibitor |
| LT2662094T (lt) | 2012-05-08 | 2024-07-10 | Onyx Therapeutics, Inc. | Ciklodekstrino kompleksodaros metodai, skirti peptidų proteasomos komponavimui |
| UY34897A (es) | 2012-07-09 | 2014-01-31 | Onyx Therapeutics Inc | Profarmacos de inhibidores peptidicos de expoxi cetona proteasa |
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