AU2004293182B2 - Compositions comprising polypeptides - Google Patents

Compositions comprising polypeptides Download PDF

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Publication number
AU2004293182B2
AU2004293182B2 AU2004293182A AU2004293182A AU2004293182B2 AU 2004293182 B2 AU2004293182 B2 AU 2004293182B2 AU 2004293182 A AU2004293182 A AU 2004293182A AU 2004293182 A AU2004293182 A AU 2004293182A AU 2004293182 B2 AU2004293182 B2 AU 2004293182B2
Authority
AU
Australia
Prior art keywords
polypeptide
multimeric
composition
antigen
antigen binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU2004293182A
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English (en)
Other versions
AU2004293182A1 (en
Inventor
Patrick Baeuerle
Frank Hanakam
Robert Hofmeister
Christian Itin
Nadja Prang
Thomas Urbig
Andreas Wolf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Research Munich GmbH
Original Assignee
Amgen Research Munich GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Research Munich GmbH filed Critical Amgen Research Munich GmbH
Publication of AU2004293182A1 publication Critical patent/AU2004293182A1/en
Application granted granted Critical
Publication of AU2004293182B2 publication Critical patent/AU2004293182B2/en
Assigned to AMGEN RESEARCH (MUNICH) GMBH reassignment AMGEN RESEARCH (MUNICH) GMBH Request to Amend Deed and Register Assignors: MICROMET AG
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2004293182A 2003-11-28 2004-11-26 Compositions comprising polypeptides Expired AU2004293182B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03027511 2003-11-28
EP03027511.9 2003-11-28
PCT/EP2004/013445 WO2005052004A2 (en) 2003-11-28 2004-11-26 Compositions comprising polypeptides

Publications (2)

Publication Number Publication Date
AU2004293182A1 AU2004293182A1 (en) 2005-06-09
AU2004293182B2 true AU2004293182B2 (en) 2010-02-18

Family

ID=34626385

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004293182A Expired AU2004293182B2 (en) 2003-11-28 2004-11-26 Compositions comprising polypeptides

Country Status (18)

Country Link
US (1) US10000574B2 (enExample)
EP (2) EP1691833B1 (enExample)
AT (1) ATE459374T1 (enExample)
AU (1) AU2004293182B2 (enExample)
BE (1) BE2016C023I2 (enExample)
CA (1) CA2544532C (enExample)
CY (2) CY1110689T1 (enExample)
DE (1) DE602004025840D1 (enExample)
DK (1) DK1691833T3 (enExample)
ES (1) ES2341252T3 (enExample)
FR (1) FR16C1000I2 (enExample)
HU (1) HUS1600019I1 (enExample)
LU (1) LU93067I2 (enExample)
NL (1) NL300807I2 (enExample)
PL (1) PL1691833T3 (enExample)
PT (1) PT1691833E (enExample)
SI (1) SI1691833T1 (enExample)
WO (1) WO2005052004A2 (enExample)

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US20150210772A1 (en) 2013-12-17 2015-07-30 Genentech, Inc. Methods of treating cancer using pd-1 axis binding antagonists and an anti-cd20 antibody
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CN107427590B (zh) 2015-02-02 2021-08-31 伯明翰大学 具有多个t细胞表位的靶向部分肽表位复合物
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MX2018008347A (es) 2016-01-08 2018-12-06 Hoffmann La Roche Metodos de tratamiento de canceres positivos para ace utilizando antagonistas de union a eje pd-1 y anticuerpos biespecificos anti-ace/anti-cd3.
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WO2018027204A1 (en) 2016-08-05 2018-02-08 Genentech, Inc. Multivalent and multiepitopic anitibodies having agonistic activity and methods of use
JP7250674B2 (ja) 2016-08-08 2023-04-03 エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト がんの治療及び診断方法
CN110087682B (zh) 2016-12-19 2023-12-15 豪夫迈·罗氏有限公司 用靶向性4-1bb(cd137)激动剂的组合疗法
BR112019007267A2 (pt) 2016-12-20 2019-07-09 Hoffmann La Roche anticorpo biespecífico anti-cd20/anti-cd3, produto farmacêutico, composição farmacêutica que compreende um anticorpo biespecífico anti-cd20/anti-cd3, uso de combinação de anticorpo biespecífico anti-cd20/anti-cd3 e um agonista de 4-1bb e método de tratamento ou retardamento da progressão de câncer em pacientes
JP2020521791A (ja) 2017-06-02 2020-07-27 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト がんの治療のためのｉｉ型抗ｃｄ２０抗体及び抗ｃｄ２０／ｃｄ３０二重特異性抗体
TW201930353A (zh) 2017-11-01 2019-08-01 瑞士商赫孚孟拉羅股份公司 使用經靶向之ox40促效劑的組合療法
WO2019175071A1 (en) 2018-03-13 2019-09-19 F. Hoffmann-La Roche Ag Therapeutic combination of 4-1 bb agonists with anti-cd20 antibodies
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JP7383704B2 (ja) * 2018-06-07 2023-11-20 カリナン オンコロジー インコーポレイテッド 多重特異性結合タンパク質およびその使用方法
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MX2023009100A (es) 2021-02-03 2023-09-25 Mozart Therapeutics Inc Agentes aglutinantes y métodos para usar los mismos.
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Also Published As

Publication number Publication date
SI1691833T1 (sl) 2010-06-30
NL300807I2 (enExample) 2016-10-13
WO2005052004A2 (en) 2005-06-09
WO2005052004A3 (en) 2006-03-09
CY2016010I2 (el) 2016-08-31
DE602004025840D1 (de) 2010-04-15
EP1691833A2 (en) 2006-08-23
US20070249529A1 (en) 2007-10-25
ATE459374T1 (de) 2010-03-15
US10000574B2 (en) 2018-06-19
FR16C1000I2 (fr) 2017-02-03
FR16C1000I1 (enExample) 2016-06-24
CA2544532C (en) 2015-06-16
EP2186527A1 (en) 2010-05-19
PL1691833T3 (pl) 2010-08-31
EP1691833B1 (en) 2010-03-03
ES2341252T3 (es) 2010-06-17
DK1691833T3 (da) 2010-05-03
HUS1600019I1 (hu) 2016-06-28
CY1110689T1 (el) 2015-06-10
CY2016010I1 (el) 2016-08-31
AU2004293182A1 (en) 2005-06-09
BE2016C023I2 (enExample) 2023-12-18
CA2544532A1 (en) 2005-06-09
LU93067I2 (fr) 2016-07-11
PT1691833E (pt) 2010-06-08

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