PT1691833E - Composições compreendendo polipéptidos - Google Patents

Composições compreendendo polipéptidos Download PDF

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Publication number
PT1691833E
PT1691833E PT04803302T PT04803302T PT1691833E PT 1691833 E PT1691833 E PT 1691833E PT 04803302 T PT04803302 T PT 04803302T PT 04803302 T PT04803302 T PT 04803302T PT 1691833 E PT1691833 E PT 1691833E
Authority
PT
Portugal
Prior art keywords
polypeptide
ser
gly
thr
antigen
Prior art date
Application number
PT04803302T
Other languages
English (en)
Portuguese (pt)
Inventor
Nadja Prang
Robert Hofmeister
Andreas Wolf
Frank Hanakam
Thomas Urbig
Christian Itin
Patrick Baeuerle
Original Assignee
Micromet Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromet Ag filed Critical Micromet Ag
Publication of PT1691833E publication Critical patent/PT1691833E/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT04803302T 2003-11-28 2004-11-26 Composições compreendendo polipéptidos PT1691833E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03027511 2003-11-28

Publications (1)

Publication Number Publication Date
PT1691833E true PT1691833E (pt) 2010-06-08

Family

ID=34626385

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04803302T PT1691833E (pt) 2003-11-28 2004-11-26 Composições compreendendo polipéptidos

Country Status (18)

Country Link
US (1) US10000574B2 (enExample)
EP (2) EP1691833B1 (enExample)
AT (1) ATE459374T1 (enExample)
AU (1) AU2004293182B2 (enExample)
BE (1) BE2016C023I2 (enExample)
CA (1) CA2544532C (enExample)
CY (2) CY1110689T1 (enExample)
DE (1) DE602004025840D1 (enExample)
DK (1) DK1691833T3 (enExample)
ES (1) ES2341252T3 (enExample)
FR (1) FR16C1000I2 (enExample)
HU (1) HUS1600019I1 (enExample)
LU (1) LU93067I2 (enExample)
NL (1) NL300807I2 (enExample)
PL (1) PL1691833T3 (enExample)
PT (1) PT1691833E (enExample)
SI (1) SI1691833T1 (enExample)
WO (1) WO2005052004A2 (enExample)

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CN107427590B (zh) 2015-02-02 2021-08-31 伯明翰大学 具有多个t细胞表位的靶向部分肽表位复合物
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CN116327953A (zh) 2015-06-17 2023-06-27 豪夫迈·罗氏有限公司 使用pd-1轴结合拮抗剂和紫杉烷治疗局部晚期或转移性乳腺癌的方法
JP7002446B2 (ja) 2015-09-21 2022-03-04 アプティーボ リサーチ アンド デベロップメント エルエルシー Cd3結合ポリペプチド
AR106188A1 (es) 2015-10-01 2017-12-20 Hoffmann La Roche Anticuerpos anti-cd19 humano humanizados y métodos de utilización
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PL3387015T3 (pl) 2015-12-09 2022-02-14 F. Hoffmann-La Roche Ag Przeciwciało anty-CD20 typu II do ograniczania tworzenia przeciwciał przeciwlekowych
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WO2018027204A1 (en) 2016-08-05 2018-02-08 Genentech, Inc. Multivalent and multiepitopic anitibodies having agonistic activity and methods of use
JP7250674B2 (ja) 2016-08-08 2023-04-03 エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト がんの治療及び診断方法
CN110087682B (zh) 2016-12-19 2023-12-15 豪夫迈·罗氏有限公司 用靶向性4-1bb(cd137)激动剂的组合疗法
BR112019007267A2 (pt) 2016-12-20 2019-07-09 Hoffmann La Roche anticorpo biespecífico anti-cd20/anti-cd3, produto farmacêutico, composição farmacêutica que compreende um anticorpo biespecífico anti-cd20/anti-cd3, uso de combinação de anticorpo biespecífico anti-cd20/anti-cd3 e um agonista de 4-1bb e método de tratamento ou retardamento da progressão de câncer em pacientes
JP2020521791A (ja) 2017-06-02 2020-07-27 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト がんの治療のためのii型抗cd20抗体及び抗cd20/cd30二重特異性抗体
TW201930353A (zh) 2017-11-01 2019-08-01 瑞士商赫孚孟拉羅股份公司 使用經靶向之ox40促效劑的組合療法
WO2019175071A1 (en) 2018-03-13 2019-09-19 F. Hoffmann-La Roche Ag Therapeutic combination of 4-1 bb agonists with anti-cd20 antibodies
TWI841551B (zh) 2018-03-13 2024-05-11 瑞士商赫孚孟拉羅股份公司 使用靶向4-1bb (cd137)之促效劑的組合療法
JP7383704B2 (ja) * 2018-06-07 2023-11-20 カリナン オンコロジー インコーポレイテッド 多重特異性結合タンパク質およびその使用方法
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WO2020096959A1 (en) 2018-11-05 2020-05-14 Genentech, Inc. Methods of producing two chain proteins in prokaryotic host cells
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KR102503349B1 (ko) 2019-05-14 2023-02-23 프로벤션 바이오, 인코포레이티드 제1형 당뇨병을 예방하기 위한 방법 및 조성물
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Also Published As

Publication number Publication date
SI1691833T1 (sl) 2010-06-30
NL300807I2 (enExample) 2016-10-13
WO2005052004A2 (en) 2005-06-09
WO2005052004A3 (en) 2006-03-09
CY2016010I2 (el) 2016-08-31
DE602004025840D1 (de) 2010-04-15
EP1691833A2 (en) 2006-08-23
AU2004293182B2 (en) 2010-02-18
US20070249529A1 (en) 2007-10-25
ATE459374T1 (de) 2010-03-15
US10000574B2 (en) 2018-06-19
FR16C1000I2 (fr) 2017-02-03
FR16C1000I1 (enExample) 2016-06-24
CA2544532C (en) 2015-06-16
EP2186527A1 (en) 2010-05-19
PL1691833T3 (pl) 2010-08-31
EP1691833B1 (en) 2010-03-03
ES2341252T3 (es) 2010-06-17
DK1691833T3 (da) 2010-05-03
HUS1600019I1 (hu) 2016-06-28
CY1110689T1 (el) 2015-06-10
CY2016010I1 (el) 2016-08-31
AU2004293182A1 (en) 2005-06-09
BE2016C023I2 (enExample) 2023-12-18
CA2544532A1 (en) 2005-06-09
LU93067I2 (fr) 2016-07-11

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