AU2004281257C1 - Substituted spirobenzazepines - Google Patents
Substituted spirobenzazepines Download PDFInfo
- Publication number
- AU2004281257C1 AU2004281257C1 AU2004281257A AU2004281257A AU2004281257C1 AU 2004281257 C1 AU2004281257 C1 AU 2004281257C1 AU 2004281257 A AU2004281257 A AU 2004281257A AU 2004281257 A AU2004281257 A AU 2004281257A AU 2004281257 C1 AU2004281257 C1 AU 2004281257C1
- Authority
- AU
- Australia
- Prior art keywords
- compound
- spiro
- ene
- aza
- carboxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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Classifications
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- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
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- C—CHEMISTRY; METALLURGY
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- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
Landscapes
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| US47937803P | 2003-06-17 | 2003-06-17 | |
| US60/479,378 | 2003-06-17 | ||
| PCT/US2004/019460 WO2005037795A2 (en) | 2003-06-17 | 2004-06-16 | Substituted spirobenzazepines |
Publications (3)
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| AU2004281257A1 AU2004281257A1 (en) | 2005-04-28 |
| AU2004281257B2 AU2004281257B2 (en) | 2010-02-04 |
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| JP2007516177A (ja) * | 2003-06-17 | 2007-06-21 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 非ペプチド置換スピロベンゾアゼピン誘導体の製造方法 |
| EP1984342A2 (en) * | 2006-01-20 | 2008-10-29 | Janssen Pharmaceutica, N.V. | Novel solid forms of (4r)-1-[4-(2-chloro-5-fluorobenzoyl)amino-3-methoxybenzoyl]-1,2,3,5-tetrahydro-spiro[4h-1-benzazepine-4,1'-[2]cyclopentene]-3'-carboxylic acid |
| JP2010504352A (ja) * | 2006-09-22 | 2010-02-12 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | バソプレッシン拮抗薬としてのスピロベンズアゼピン類 |
| ATE532786T1 (de) * | 2006-09-22 | 2011-11-15 | Janssen Pharmaceutica Nv | Spirobenzazepine als vasopressinantagonisten |
| AR066834A1 (es) * | 2007-06-06 | 2009-09-16 | Janssen Pharmaceutica Nv | Espirobenzoazepanos como antagonistas de vasopresina, composiciones farmaceuticas que los contienen, proceso de preparacion y usos para el tratamiento de afecciones cardiacas, renales y del sistema nervioso central. |
| WO2009061786A2 (en) * | 2007-11-07 | 2009-05-14 | Janssen Pharmaceutica N.V. | Combination therapy comprising angiotensin converting enzyme inhibitors and vasopressin receptor antagonists |
| WO2014062888A1 (en) | 2012-10-18 | 2014-04-24 | University Of South Florida | Compositions and methods for treating stroke |
| RU2642783C2 (ru) | 2012-12-26 | 2018-01-26 | Санва Кагаку Кенкюсо Ко., Лтд. | Новое производное бензоазепина и его медицинское применение |
| US20240190884A1 (en) * | 2021-03-05 | 2024-06-13 | Shanghai Jemincare Pharmaceutical Co., Ltd | New-type benzazepine fused ring derivative |
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| WO2002002531A1 (en) * | 2000-07-05 | 2002-01-10 | Ortho-Mcneil Pharmaceutical, Inc. | Nonpeptide substituted spirobenzoazepines as vasopressin antagonists |
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