AU2004248140A1 - Gene expression markers for response to EGFR inhibitor drugs - Google Patents
Gene expression markers for response to EGFR inhibitor drugs Download PDFInfo
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- AU2004248140A1 AU2004248140A1 AU2004248140A AU2004248140A AU2004248140A1 AU 2004248140 A1 AU2004248140 A1 AU 2004248140A1 AU 2004248140 A AU2004248140 A AU 2004248140A AU 2004248140 A AU2004248140 A AU 2004248140A AU 2004248140 A1 AU2004248140 A1 AU 2004248140A1
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| US20050267689A1 (en) * | 2003-07-07 | 2005-12-01 | Maxim Tsypin | Method to automatically identify peak and monoisotopic peaks in mass spectral data for biomolecular applications |
| JP4708342B2 (ja) | 2003-07-25 | 2011-06-22 | デックスコム・インコーポレーテッド | 埋設可能な装置に用いる酸素増大膜システム |
| WO2005070020A2 (en) | 2004-01-23 | 2005-08-04 | The Regents Of The University Of Colorado | Gefitinib sensitivity-related gene expression and products and methods related thereto |
| ES2553264T3 (es) * | 2004-05-27 | 2015-12-07 | The Regents Of The University Of Colorado | Métodos para la predicción del resultado clínico para inhibidores del receptor del factor de crecimiento epidérmico para pacientes de cáncer |
| EP2592155B2 (en) | 2004-06-04 | 2019-09-11 | Genentech, Inc. | EGFR mutations |
| US8383357B2 (en) | 2005-03-16 | 2013-02-26 | OSI Pharmaceuticals, LLC | Biological markers predictive of anti-cancer response to epidermal growth factor receptor kinase inhibitors |
| WO2006101925A2 (en) | 2005-03-16 | 2006-09-28 | Osi Pharmaceuticals, Inc. | Biological markers predictive of anti-cancer response to epidermal growth factor receptor kinase inhibitors |
| CN102007220A (zh) | 2005-04-01 | 2011-04-06 | 安姆根有限公司 | 表皮生长因子受体基因拷贝数 |
| JP2008535853A (ja) * | 2005-04-07 | 2008-09-04 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド | 癌関連遺伝子 |
| CN101155932A (zh) * | 2005-04-14 | 2008-04-02 | 默克专利有限公司 | 基于在肿瘤组织中增加的egfr基因拷贝数的抗egfr抗体治疗 |
| US20060252082A1 (en) * | 2005-05-04 | 2006-11-09 | University Of South Florida | Predicting treatment response in cancer subjects |
| WO2007001868A1 (en) * | 2005-06-28 | 2007-01-04 | Genentech, Inc. | Egfr and kras mutations |
| AU2006292278B2 (en) | 2005-09-20 | 2012-03-08 | Osi Pharmaceuticals, Inc. | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors |
| CA2642542C (en) * | 2006-02-16 | 2012-09-25 | Ventana Medical Systems, Inc. | Reagents and methods for cancer prognosis and pathological staging |
| US20070207467A1 (en) * | 2006-03-01 | 2007-09-06 | Ming Xu | Detection of lymph node metastasis from gastric carcinoma |
| JP2007252312A (ja) * | 2006-03-24 | 2007-10-04 | Japan Health Science Foundation | 上皮成長因子受容体−チロシンキナーゼ阻害剤に対する肺ガンの感度測定方法および肺ガン治療剤のスクリーニング方法 |
| US7858389B2 (en) * | 2006-03-31 | 2010-12-28 | Biodesix, Inc. | Selection of non-small-cell lung cancer patients for treatment with monoclonal antibody drugs targeting EGFR pathway |
| US7858390B2 (en) * | 2006-03-31 | 2010-12-28 | Biodesix, Inc. | Selection of colorectal cancer patients for treatment with drugs targeting EGFR pathway |
| US7867775B2 (en) * | 2006-03-31 | 2011-01-11 | Biodesix, Inc. | Selection of head and neck cancer patients for treatment with drugs targeting EGFR pathway |
| US7736905B2 (en) * | 2006-03-31 | 2010-06-15 | Biodesix, Inc. | Method and system for determining whether a drug will be effective on a patient with a disease |
| US7906342B2 (en) * | 2006-03-31 | 2011-03-15 | Biodesix, Inc. | Monitoring treatment of cancer patients with drugs targeting EGFR pathway using mass spectrometry of patient samples |
| US8024282B2 (en) * | 2006-03-31 | 2011-09-20 | Biodesix, Inc. | Method for reliable classification of samples in clinical diagnostics using an improved method of classification |
| US8768629B2 (en) | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
| BRPI0711011A2 (pt) | 2006-05-18 | 2011-08-23 | Molecular Profiling Inst Inc | método para a determinação da intervenção médica para um estado de doença, método para a identificação de uma terapia de droga com capacidade de interação com um alvo molecular e sistema para a determinação da intervenção médica individualizada para um estado de doença |
| US20070281305A1 (en) * | 2006-06-05 | 2007-12-06 | Sean Wuxiong Cao | Detection of lymph node metastasis from gastric carcinoma |
| EP2061906B1 (en) * | 2006-09-12 | 2011-08-31 | Genentech, Inc. | Methods and compositions for the diagnosis and treatment of lung cancer using pdgfra, kit or kdr gene as genetic marker |
| HRP20140360T4 (hr) | 2007-03-13 | 2022-06-10 | Amgen, Inc. | K-ras mutacije i terapija anti-egfr antitijelom |
| JP5240739B2 (ja) | 2007-04-13 | 2013-07-17 | オーエスアイ・フアーマシユーテイカルズ・エル・エル・シー | キナーゼ阻害剤に対する抗癌応答を予測する生物学的マーカー |
| WO2009023172A2 (en) * | 2007-08-09 | 2009-02-19 | The Johns Hopkins University | Predictions of responsiveness to egfr inhibitors |
| CN101855364B (zh) * | 2007-08-14 | 2013-04-17 | 霍夫曼-拉罗奇有限公司 | Egfr抑制剂治疗的预测性标记物 |
| PL2179056T3 (pl) * | 2007-08-14 | 2013-02-28 | Hoffmann La Roche | Wskaźnik leczenia inhibitorem EGRF |
| BRPI0815546A2 (pt) * | 2007-08-14 | 2015-02-10 | Hoffmann La Roche | Marcador preditivo para tratamento com inibidor da egfr |
| MX2010001577A (es) * | 2007-08-14 | 2010-06-02 | Hoffmann La Roche | Marcador predictivo para tratamiento con el inhibidor del receptor del factor de crecimiento epidermico. |
| WO2009021679A1 (en) * | 2007-08-14 | 2009-02-19 | F. Hoffmann-La Roche Ag | Predictive marker for egfr inhibitor treamtent |
| JP5368445B2 (ja) | 2007-08-14 | 2013-12-18 | エフ．ホフマン−ラ ロシュ アーゲー | Ｅｇｆｒ阻害因子治療のための予測マーカー |
| CA2694356A1 (en) | 2007-10-03 | 2009-04-09 | Osi Pharmaceuticals, Inc. | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors |
| AU2008307634A1 (en) | 2007-10-03 | 2009-04-09 | Osi Pharmaceuticals, Inc. | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors |
| AU2009246398A1 (en) * | 2008-05-14 | 2009-11-19 | Bristol-Myers Squibb Company | Predictors of patient response to treatment with EGF receptor inhibitors |
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| WO2010015535A1 (en) * | 2008-08-05 | 2010-02-11 | F. Hoffmann-La Roche Ag | Predictive marker for egfr inhibitor treatment |
| WO2010015536A1 (en) * | 2008-08-05 | 2010-02-11 | F. Hoffmann-La Roche Ag | Predictive marker for egfr inhibitor treatment |
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- 2004-05-28 EP EP10158352A patent/EP2226396A1/en not_active Withdrawn
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| EP1636380A2 (en) | 2006-03-22 |
| WO2004111273A3 (en) | 2005-10-06 |
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| CA2527321A1 (en) | 2004-12-23 |
| WO2004111273A2 (en) | 2004-12-23 |
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| US20080318230A1 (en) | 2008-12-25 |
| AU2009248449A1 (en) | 2010-01-07 |
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