AU2004241749B2 - Composition comprising a PDE4 inhibitor and a PDE5 inhibitor - Google Patents
Composition comprising a PDE4 inhibitor and a PDE5 inhibitor Download PDFInfo
- Publication number
- AU2004241749B2 AU2004241749B2 AU2004241749A AU2004241749A AU2004241749B2 AU 2004241749 B2 AU2004241749 B2 AU 2004241749B2 AU 2004241749 A AU2004241749 A AU 2004241749A AU 2004241749 A AU2004241749 A AU 2004241749A AU 2004241749 B2 AU2004241749 B2 AU 2004241749B2
- Authority
- AU
- Australia
- Prior art keywords
- pharmaceutically acceptable
- methyl
- inhibitor
- phenyl
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- 239000002587 phosphodiesterase IV inhibitor Substances 0.000 title claims description 107
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Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03011609 | 2003-05-22 | ||
| EP03011609.9 | 2003-05-22 | ||
| PCT/EP2004/050869 WO2004103407A2 (en) | 2003-05-22 | 2004-05-19 | Composition comprising a pde4 inhibitor and a pde5 inhibitor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2004241749A1 AU2004241749A1 (en) | 2004-12-02 |
| AU2004241749B2 true AU2004241749B2 (en) | 2010-03-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2004241749A Ceased AU2004241749B2 (en) | 2003-05-22 | 2004-05-19 | Composition comprising a PDE4 inhibitor and a PDE5 inhibitor |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US20060094723A1 (enExample) |
| EP (1) | EP1628682B1 (enExample) |
| JP (1) | JP2006528229A (enExample) |
| KR (1) | KR20060012004A (enExample) |
| CN (1) | CN1791429A (enExample) |
| AU (1) | AU2004241749B2 (enExample) |
| BR (1) | BRPI0410326A (enExample) |
| CA (1) | CA2525946C (enExample) |
| CO (1) | CO5660275A2 (enExample) |
| EA (1) | EA012279B1 (enExample) |
| EC (1) | ECSP056173A (enExample) |
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| IL (1) | IL171306A (enExample) |
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| MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
| MXPA04008070A (es) | 2003-03-10 | 2004-11-26 | Altana Pharma Ag | Novedoso proceso para la preparacion de roflumilasto. |
| WO2005023253A1 (en) | 2003-09-05 | 2005-03-17 | Altana Pharma Ag | Use of pde4 inhibitors for the treatment of diabetes mellitus |
| WO2005107749A1 (en) * | 2004-05-10 | 2005-11-17 | Altana Pharma Ag | Use of roflumilast for the prophylaxis or treatment of emphysema |
| MX2007010560A (es) * | 2005-03-08 | 2008-02-21 | Nycomed Gmbh | Roflumilast para el tratamiento de diabetes mellitus. |
| WO2006094942A1 (en) * | 2005-03-08 | 2006-09-14 | Nycomed Gmbh | Roflumilast for the treatment of diabetes mellitus |
| US8663694B2 (en) | 2005-03-16 | 2014-03-04 | Takeda Gmbh | Taste masked dosage form containing roflumilast |
| DE102005016345A1 (de) * | 2005-04-09 | 2006-10-12 | Bayer Healthcare Ag | Neue Verwendung von 2-Phenyl-substituierten Imidazotriazinon-Derivaten |
| CA2604295C (en) * | 2005-04-19 | 2014-10-07 | Nycomed Gmbh | Roflumilast for the treatment of pulmonary hypertension |
| NL2000291C2 (nl) | 2005-11-10 | 2009-02-17 | Pfizer Prod Inc | 1-(1-(2-ethoxyethyl)-3-ethyl-7-(4-methylpyridin-2-ylamino)-1H- pyrazool(4,3-d)pyrimidine-5-yl)piperidine-4-carbonzuur en zouten daarvan. |
| UA106422C2 (uk) * | 2006-07-05 | 2014-08-26 | Такеда Гмбх | КОМБІНОВАНЕ ЗАСТОСУВАННЯ ІНГІБІТОРА PDE4 ТА ІНГІБІТОРА HMG-CоA-РЕДУКТАЗИ ДЛЯ ПРОФІЛАКТИКИ АБО ЗЦІЛЮВАЛЬНОГО ЛІКУВАННЯ ЗАПАЛЬНОГО ЗАХВОРЮВАННЯ ЛЕГЕНІВ |
| CN101547922B (zh) * | 2006-10-04 | 2012-06-20 | 辉瑞产品公司 | 作为钙受体拮抗剂的吡啶并[4,3-d]嘧啶-4(3H)-酮衍生物 |
| WO2010013925A2 (en) * | 2008-07-31 | 2010-02-04 | Dong-A Pharmaceutical. Co., Ltd. | Pharmacological composition for prevention and treatment of respiratory disease containing pyrazolopyrimidinone compound or pharmaceutically acceptable salts thereof |
| JP2014526461A (ja) * | 2011-09-09 | 2014-10-06 | エスケー ケミカルズ カンパニー，リミテッド | Ｐｄｅ５抑制剤を含む皮膚しわ改善用組成物 |
| JP6225178B2 (ja) * | 2012-05-31 | 2017-11-01 | フェネックス ファーマシューティカルス アーゲー | オーファン核内受容体ＲＯＲγの調整剤としてのカルボキサミドまたはスルホンアミド置換されたチアゾールおよび関連する誘導体 |
| WO2015089105A1 (en) | 2013-12-09 | 2015-06-18 | Respira Therapeutics, Inc. | Pde5 inhibitor powder formulations and methods relating thereto |
| EP3165224A1 (en) | 2015-11-09 | 2017-05-10 | Albert-Ludwigs-Universität Freiburg | Use of pde4 inhibitors for the prophylaxis and/or therapy of dyslipoproteinaemia and related disorders |
| US10058545B2 (en) * | 2016-08-09 | 2018-08-28 | Cipla Limited | Method of treating pulmonary arterial hypertension |
| CN107648224A (zh) * | 2017-10-31 | 2018-02-02 | 泰州中国医药城中医药研究院 | 一种治疗和预防心力衰竭药物及其在制药中的应用 |
| US20210031012A1 (en) | 2018-01-26 | 2021-02-04 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a pde4 inhibitor |
| CN108976107B (zh) * | 2018-08-23 | 2021-03-23 | 南方医科大学 | 3-芳基-4-烷氧基苄胺衍生物及其制备方法和应用 |
| WO2020106704A2 (en) | 2018-11-19 | 2020-05-28 | Progenity, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
| CN121197633A (zh) | 2019-12-13 | 2025-12-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| US20230124467A1 (en) * | 2020-03-03 | 2023-04-20 | Mios Pharmaceuticals Limited | Compounds and methods for treating diseases and/or conditions caused by coronavirus |
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| WO2002064584A1 (en) * | 2001-02-15 | 2002-08-22 | Altana Pharma Ag | Phthalayinone-piperidino-derivatives as pde4 inhibitors |
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| GB9013750D0 (en) | 1990-06-20 | 1990-08-08 | Pfizer Ltd | Therapeutic agents |
| HU220041B (hu) | 1993-07-02 | 2001-10-28 | Byk Gulden Lomberg Chemische Fabrik Gmbh. | Fluor-alkoxi-helyettesített benzamidszármazékok, eljárás előállításukra és ezeket a vegyületeket tartalmazó gyógyászati készítmények |
| GB9401090D0 (en) | 1994-01-21 | 1994-03-16 | Glaxo Lab Sa | Chemical compounds |
| EP0779292A4 (en) * | 1994-08-29 | 1997-09-24 | Yamanouchi Pharma Co Ltd | NEW NAPHTHYRIDE DERIVATIVES AND MEDICAL COMPOSITIONS CONTAINING THEM |
| US6127363A (en) * | 1997-10-28 | 2000-10-03 | Vivus, Inc. | Local administration of Type IV phosphodiesterase inhibitors for the treatment of erectile dysfunction |
| US6362178B1 (en) | 1997-11-12 | 2002-03-26 | Bayer Aktiengesellschaft | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors |
| US6417190B1 (en) * | 1998-12-17 | 2002-07-09 | Boehringer Ingelheim Pharma Kg | Tricyclic nitrogen heterocycles as PDE IV inhibitors |
| TWI224966B (en) * | 1999-11-02 | 2004-12-11 | Pfizer | Pharmaceutical composition (I) useful for treating or preventing pulmonary hypertension in a patient |
| AU2002314102A1 (en) * | 2001-05-25 | 2002-12-09 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Combination of a pde4 inhibitor and tiotropium or derivate thereof for treating obstructive airways |
| US20030114469A1 (en) * | 2001-09-27 | 2003-06-19 | Cohen David Saul | Combinations |
| GB0202254D0 (en) * | 2002-01-31 | 2002-03-20 | Pfizer Ltd | Prevention of scarring |
| US20030216407A1 (en) * | 2002-01-31 | 2003-11-20 | Pfizer Inc. | Use of PDE5 inhibitors in the treatment of scarring |
| MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
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2004
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- 2004-05-19 UA UAA200511710A patent/UA83041C2/ru unknown
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- 2004-05-19 CN CNA2004800133493A patent/CN1791429A/zh active Pending
- 2004-05-19 KR KR1020057021796A patent/KR20060012004A/ko not_active Ceased
- 2004-05-19 BR BRPI0410326-2A patent/BRPI0410326A/pt active Search and Examination
- 2004-05-19 RS YU20050858A patent/RS52730B/sr unknown
- 2004-05-19 EA EA200501690A patent/EA012279B1/ru not_active IP Right Cessation
- 2004-05-19 US US10/556,888 patent/US20060094723A1/en not_active Abandoned
- 2004-05-19 JP JP2006530210A patent/JP2006528229A/ja active Pending
- 2004-05-19 WO PCT/EP2004/050869 patent/WO2004103407A2/en not_active Ceased
- 2004-05-19 AU AU2004241749A patent/AU2004241749B2/en not_active Ceased
- 2004-05-19 GE GEAP20049115A patent/GEP20084342B/en unknown
- 2004-05-19 NZ NZ544040A patent/NZ544040A/en not_active IP Right Cessation
- 2004-05-19 MX MXPA05012302A patent/MXPA05012302A/es active IP Right Grant
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- 2005-10-09 IL IL171306A patent/IL171306A/en not_active IP Right Cessation
- 2005-10-18 TN TNP2005000265A patent/TNSN05265A1/en unknown
- 2005-11-17 EC EC2005006173A patent/ECSP056173A/es unknown
- 2005-12-12 MA MA28653A patent/MA27855A1/fr unknown
- 2005-12-14 IS IS8181A patent/IS8181A/is unknown
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- 2005-12-16 CO CO05126935A patent/CO5660275A2/es active IP Right Grant
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| WO2002064584A1 (en) * | 2001-02-15 | 2002-08-22 | Altana Pharma Ag | Phthalayinone-piperidino-derivatives as pde4 inhibitors |
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Also Published As
| Publication number | Publication date |
|---|---|
| EP1628682A2 (en) | 2006-03-01 |
| NO20055941L (no) | 2005-12-14 |
| RS20050858A (sr) | 2007-12-31 |
| AU2004241749A1 (en) | 2004-12-02 |
| RS52730B (sr) | 2013-08-30 |
| MXPA05012302A (es) | 2006-01-30 |
| UA83041C2 (ru) | 2008-06-10 |
| CA2525946C (en) | 2013-01-29 |
| ECSP056173A (es) | 2006-04-19 |
| EP1628682B1 (en) | 2013-09-25 |
| TNSN05265A1 (en) | 2007-07-10 |
| MA27855A1 (fr) | 2006-04-03 |
| US20100234382A1 (en) | 2010-09-16 |
| NZ544040A (en) | 2009-03-31 |
| BRPI0410326A (pt) | 2006-05-23 |
| IL171306A (en) | 2013-08-29 |
| JP2006528229A (ja) | 2006-12-14 |
| CN1791429A (zh) | 2006-06-21 |
| US20120196867A1 (en) | 2012-08-02 |
| KR20060012004A (ko) | 2006-02-06 |
| WO2004103407A3 (en) | 2005-02-17 |
| CO5660275A2 (es) | 2006-07-31 |
| EA200501690A1 (ru) | 2006-06-30 |
| WO2004103407A2 (en) | 2004-12-02 |
| ZA200508116B (en) | 2007-01-31 |
| CA2525946A1 (en) | 2004-12-02 |
| GEP20084342B (en) | 2008-03-25 |
| EA012279B1 (ru) | 2009-08-28 |
| NO333501B1 (no) | 2013-06-24 |
| US20060094723A1 (en) | 2006-05-04 |
| IS8181A (is) | 2005-12-14 |
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