AU2003298726A1 - Peptides which target tumor and endothelial cells, compositions and uses thereof - Google Patents

Peptides which target tumor and endothelial cells, compositions and uses thereof Download PDF

Info

Publication number
AU2003298726A1
AU2003298726A1 AU2003298726A AU2003298726A AU2003298726A1 AU 2003298726 A1 AU2003298726 A1 AU 2003298726A1 AU 2003298726 A AU2003298726 A AU 2003298726A AU 2003298726 A AU2003298726 A AU 2003298726A AU 2003298726 A1 AU2003298726 A1 AU 2003298726A1
Authority
AU
Australia
Prior art keywords
compound
hydrogen
substituted
acyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003298726A
Other languages
English (en)
Inventor
Amy L. Allan
Fernando Donate
Patricia L. Gladstone
Andrew Mazar
Graham Parry
Robert J. Ternansky
Won Hyung Yoon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tactic Pharma LLC
Original Assignee
Attenuon LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Attenuon LLC filed Critical Attenuon LLC
Publication of AU2003298726A1 publication Critical patent/AU2003298726A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
AU2003298726A 2002-11-25 2003-11-25 Peptides which target tumor and endothelial cells, compositions and uses thereof Abandoned AU2003298726A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42917402P 2002-11-25 2002-11-25
US60/429,174 2002-11-25
US47553903P 2003-06-02 2003-06-02
US60/475,539 2003-06-02
PCT/US2003/037895 WO2004063213A2 (en) 2002-11-25 2003-11-25 Peptides which target tumor and endothelial cells, compositions and uses thereof

Publications (1)

Publication Number Publication Date
AU2003298726A1 true AU2003298726A1 (en) 2004-08-10

Family

ID=32397181

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2003298726A Abandoned AU2003298726A1 (en) 2002-11-25 2003-11-25 Peptides which target tumor and endothelial cells, compositions and uses thereof
AU2003297609A Abandoned AU2003297609A1 (en) 2002-11-25 2003-11-25 Peptides which inhibit angiogenesis, cell migration, cell invasion and cell proliferation, compositions and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2003297609A Abandoned AU2003297609A1 (en) 2002-11-25 2003-11-25 Peptides which inhibit angiogenesis, cell migration, cell invasion and cell proliferation, compositions and uses thereof

Country Status (14)

Country Link
US (2) US7517855B2 (enExample)
EP (2) EP1569678A4 (enExample)
JP (2) JP2006514116A (enExample)
KR (2) KR20050096917A (enExample)
AU (2) AU2003298726A1 (enExample)
BR (2) BR0316523A (enExample)
CA (2) CA2507045A1 (enExample)
EA (2) EA200500871A1 (enExample)
HR (2) HRP20050584A2 (enExample)
MX (2) MXPA05005469A (enExample)
NO (2) NO20053111L (enExample)
NZ (2) NZ540363A (enExample)
PL (2) PL377763A1 (enExample)
WO (2) WO2004047771A2 (enExample)

Families Citing this family (19)

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WO2004047771A2 (en) * 2002-11-25 2004-06-10 Attenuon, Llc. Peptides which inhibit angiogenesis, cell migration, cell invasion and cell proliferation, compositions and uses thereof
EP1766405A1 (en) * 2004-05-21 2007-03-28 MDS Inc. doing Business Through Its MDS Pharma Services Division Method of quantifying the cell-binding properties of a medical device
US20060078535A1 (en) * 2004-10-13 2006-04-13 The Regents Of The University Of Michigan Anticancer compounds and methods
JP2008528635A (ja) 2005-02-01 2008-07-31 アテニュオン,エルエルシー Ac−PHSCN−NH2の酸付加塩
KR20070100832A (ko) * 2005-02-01 2007-10-11 아테뉴온, 엘엘씨 항혈관신생 phscn 펩티드를 함유하는 조성물
CA2668500C (en) * 2006-11-08 2018-07-31 Chongxi Yu Transdermal delivery systems of peptides and related compounds
AU2016213759B2 (en) * 2006-11-08 2018-03-29 Chongxi Yu Transdermal delivery systems of peptides and related compounds
EP4067370A1 (en) 2009-05-08 2022-10-05 Chongxi Yu High penetration prodrug compositions of peptides and peptide related compounds
KR101228668B1 (ko) 2010-09-17 2013-01-31 가톨릭대학교 산학협력단 혈관신생 억제 활성을 갖는 펩타이드 및 이의 용도
GB2510488B (en) 2011-06-23 2020-04-08 Univ Texas Identifying peptides at the single molecule level
US11435358B2 (en) 2011-06-23 2022-09-06 Board Of Regents, The University Of Texas System Single molecule peptide sequencing
CN102417540A (zh) * 2011-11-21 2012-04-18 中国药科大学 一种聚乙二醇修饰的整合素阻断剂hm-3及其应用
EP2846847B1 (en) * 2012-05-11 2020-03-25 C.P. Medical Corporation Biocompatible hydrogel treatments for retinal detachment
CA2875369C (en) 2012-06-04 2017-11-21 Suncor Energy Inc. Formulations containing paraffinic oil and anti-settling agent
EP2967056B1 (en) 2013-03-15 2018-02-21 Suncor Energy Inc. Herbicidal compositions
JP5970439B2 (ja) * 2013-09-20 2016-08-17 チョンシー ユー ペプチド及び関連化合物の経皮送達システム
EP3543703A1 (en) * 2014-09-15 2019-09-25 Board of Regents, The University of Texas System Improved single molecule peptide sequencing
EP3821010A4 (en) 2018-07-12 2022-04-20 Board of Regents, The University of Texas System Molecular neighborhood detection by oligonucleotides
JP7588289B2 (ja) 2019-02-15 2024-11-22 ニュートリエン・エージー・ソリューションズ・(カナダ)・インコーポレイテッド 植物の健康を増進するプロトポルフィリンix誘導体及びその使用

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EP0051682B1 (en) * 1980-05-13 1984-09-05 Mitsubishi Kasei Corporation Cysteine derivatives and process for their preparation
US4440788A (en) * 1980-05-13 1984-04-03 Mitsubishi Chemical Industries, Limited Cysteine derivatives
US4394519A (en) * 1982-01-19 1983-07-19 Research Corporation Amino acid blocking agents
GB8504253D0 (en) * 1985-02-19 1985-03-20 Ici Plc Electrostatic spraying apparatus
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
DE3815221C2 (de) * 1988-05-04 1995-06-29 Gradinger F Hermes Pharma Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen
US5091176A (en) * 1988-11-02 1992-02-25 W. R. Grace & Co.-Conn. Polymer-modified peptide drugs having enhanced biological and pharmacological activities
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
US5229366A (en) * 1990-10-23 1993-07-20 Fuji Photo Film Co., Ltd. Peptide-containing polyethylene glycol derivatives and application thereof
US5149801A (en) * 1990-11-21 1992-09-22 The Regents Of The University Of California Boronated porphyrin compounds
US5561220A (en) * 1991-02-08 1996-10-01 Diatech, Inc. Technetium-99m labeled peptides for imaging inflammation
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US6001965A (en) * 1996-11-21 1999-12-14 The Regents Of The University Of Michigan Anticancer compounds and methods
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WO2004047771A2 (en) * 2002-11-25 2004-06-10 Attenuon, Llc. Peptides which inhibit angiogenesis, cell migration, cell invasion and cell proliferation, compositions and uses thereof

Also Published As

Publication number Publication date
NO20053111D0 (no) 2005-06-24
NZ540889A (en) 2008-09-26
NZ540363A (en) 2007-11-30
PL377701A1 (pl) 2006-02-06
NO20053112L (no) 2005-08-05
WO2004063213A3 (en) 2005-03-03
EP1594521A2 (en) 2005-11-16
NO20053111L (no) 2005-08-24
HRP20050585A2 (en) 2006-02-28
EP1594521A4 (en) 2008-01-09
US20050020810A1 (en) 2005-01-27
EP1569678A4 (en) 2008-01-02
MXPA05005545A (es) 2005-10-18
WO2004047771A3 (en) 2005-09-15
US20040162239A1 (en) 2004-08-19
US7517855B2 (en) 2009-04-14
PL377763A1 (pl) 2006-02-20
KR20050097494A (ko) 2005-10-07
HRP20050584A2 (hr) 2006-04-30
KR20050096917A (ko) 2005-10-06
BR0316550A (pt) 2005-10-04
MXPA05005469A (es) 2005-09-08
EA200500871A1 (ru) 2006-04-28
WO2004063213A2 (en) 2004-07-29
JP2006514116A (ja) 2006-04-27
BR0316523A (pt) 2005-10-18
JP2006515866A (ja) 2006-06-08
NO20053112D0 (no) 2005-06-24
CA2507045A1 (en) 2004-06-10
AU2003297609A1 (en) 2004-06-18
EA200500870A1 (ru) 2006-04-28
EP1569678A2 (en) 2005-09-07
WO2004047771A2 (en) 2004-06-10
CA2506813A1 (en) 2004-07-29

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application