AU2003282731B2 - Human papillomavirus polypeptides and immunogenic compositions - Google Patents

Human papillomavirus polypeptides and immunogenic compositions Download PDF

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Publication number
AU2003282731B2
AU2003282731B2 AU2003282731A AU2003282731A AU2003282731B2 AU 2003282731 B2 AU2003282731 B2 AU 2003282731B2 AU 2003282731 A AU2003282731 A AU 2003282731A AU 2003282731 A AU2003282731 A AU 2003282731A AU 2003282731 B2 AU2003282731 B2 AU 2003282731B2
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seq
polypeptide
sequence
amino acids
mutations
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AU2003282731A1 (en
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Maria Cristina Cassetti
Susan P. Mcelhiney
Jeffrey K. Pullen
Larry Smith
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Wyeth Holdings LLC
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Wyeth Holdings LLC
Wyeth LLC
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01DNA viruses
    • C07K14/025Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
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    • A61P35/00Antineoplastic agents
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
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    • C12N2710/20011Papillomaviridae
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    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
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    • C12N2770/00011Details
    • C12N2770/36011Togaviridae
    • C12N2770/36111Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36141Use of virus, viral particle or viral elements as a vector
    • C12N2770/36143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Microbiology (AREA)
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  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Diabetes (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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AU2003282731A 2002-10-03 2003-10-02 Human papillomavirus polypeptides and immunogenic compositions Expired AU2003282731B2 (en)

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US41592902P 2002-10-03 2002-10-03
US60/415,929 2002-10-03
PCT/US2003/031726 WO2004030636A2 (en) 2002-10-03 2003-10-02 Human papillomavirus polypeptides and immunogenic compositions

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AU2003282731A1 AU2003282731A1 (en) 2004-04-23
AU2003282731B2 true AU2003282731B2 (en) 2009-01-08

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EP (1) EP1553966B1 (enExample)
JP (2) JP4755422B2 (enExample)
KR (1) KR101145190B1 (enExample)
CN (1) CN1720060B (enExample)
AU (1) AU2003282731B2 (enExample)
BR (1) BR0314529A (enExample)
CA (1) CA2499837C (enExample)
CO (1) CO5700784A2 (enExample)
DK (1) DK1553966T3 (enExample)
ES (1) ES2391451T3 (enExample)
MX (1) MXPA05003395A (enExample)
NZ (1) NZ556544A (enExample)
PT (1) PT1553966E (enExample)
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WO2004030636A3 (en) 2005-02-24
ZA200502618B (en) 2008-10-29
MXPA05003395A (es) 2005-06-22
EP1553966B1 (en) 2012-08-01
CN1720060A (zh) 2006-01-11
DK1553966T3 (da) 2012-09-17
US7223408B2 (en) 2007-05-29
JP2006501825A (ja) 2006-01-19
US7378099B2 (en) 2008-05-27
US20070275003A1 (en) 2007-11-29
WO2004030636A2 (en) 2004-04-15
CA2499837C (en) 2013-12-03
JP2010279386A (ja) 2010-12-16
CA2499837A1 (en) 2004-04-15
NZ556544A (en) 2008-11-28
BR0314529A (pt) 2005-08-09
US20060014926A1 (en) 2006-01-19
ES2391451T3 (es) 2012-11-26
JP4755422B2 (ja) 2011-08-24
EP1553966A4 (en) 2008-04-16
KR101145190B1 (ko) 2012-05-14
KR20050053732A (ko) 2005-06-08
AU2003282731A1 (en) 2004-04-23
PT1553966E (pt) 2012-10-22
JP5398665B2 (ja) 2014-01-29
CO5700784A2 (es) 2006-11-30
EP1553966A2 (en) 2005-07-20
CN1720060B (zh) 2011-12-14

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