AU2003270087B2 - Akt inhibitors, pharmaceutical compositions, and uses thereof - Google Patents
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- AU2003270087B2 AU2003270087B2 AU2003270087A AU2003270087A AU2003270087B2 AU 2003270087 B2 AU2003270087 B2 AU 2003270087B2 AU 2003270087 A AU2003270087 A AU 2003270087A AU 2003270087 A AU2003270087 A AU 2003270087A AU 2003270087 B2 AU2003270087 B2 AU 2003270087B2
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Classifications
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- C07C43/02—Ethers
- C07C43/18—Ethers having an ether-oxygen atom bound to a carbon atom of a ring other than a six-membered aromatic ring
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
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- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Cardiology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US40723902P | 2002-09-03 | 2002-09-03 | |
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| PCT/US2003/027607 WO2004022569A1 (en) | 2002-09-03 | 2003-09-03 | Akt inhibitors, pharmaceutical compositions, and uses thereof |
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| AU2003270087A1 AU2003270087A1 (en) | 2004-03-29 |
| AU2003270087B2 true AU2003270087B2 (en) | 2009-04-23 |
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| JP (1) | JP4641796B2 (enExample) |
| AU (1) | AU2003270087B2 (enExample) |
| CA (1) | CA2497572C (enExample) |
| WO (1) | WO2004022569A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2774959C (en) | 2000-08-04 | 2016-05-31 | Dmi Biosciences, Inc. | Method of using diketopiperazines and composition containing them |
| ATE520981T1 (de) * | 2002-10-02 | 2011-09-15 | Dmi Biosciences Inc | Diagnose und überwachung von krankheiten |
| EP2517722B1 (en) | 2003-05-15 | 2016-03-02 | Ampio Pharmaceuticals, Inc. | Synthesis of diketopiperazines |
| WO2008070823A2 (en) * | 2006-12-07 | 2008-06-12 | University Of South Florida | Substrate-mimetic akt inhibitor |
| US20100048914A1 (en) | 2008-03-14 | 2010-02-25 | Angela Brodie | Novel C-17-Heteroaryl Steroidal Cyp17 Inhibitors/Antiandrogens, In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity |
| JP5856843B2 (ja) * | 2008-05-27 | 2016-02-10 | アンピオ ファーマシューティカルズ，インコーポレイテッド | ジケトピペラジンを用いた医薬組成物 |
| BRPI1008745A2 (pt) | 2009-02-05 | 2019-09-17 | Tokai Pharmaceuticals Inc | pró-fármacos de inibidores esteroidais de cyp17/antiandrogênios |
| WO2012033792A2 (en) | 2010-09-07 | 2012-03-15 | Dmi Acquisition Corp. | Treatment of diseases |
| EA028343B1 (ru) | 2011-10-10 | 2017-11-30 | Ампио Фармасьютикалз, Инк. | Лечение дегенеративного заболевания сустава |
| PH12014500686A1 (en) | 2011-10-10 | 2020-12-18 | Ampio Pharmaceuticals Inc | Implantable medical devices with increased immune tolerance, and methods for making and implanting |
| MX355446B (es) | 2011-10-28 | 2018-04-18 | Ampio Pharmaceuticals Inc | Tratamiento de rinitis. |
| CN105682662A (zh) | 2013-03-14 | 2016-06-15 | 马里兰大学巴尔的摩校区 | 雄激素受体减量调节剂及其用途 |
| US9808454B2 (en) | 2013-03-15 | 2017-11-07 | Ampio Pharmaceuticals, Inc. | Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same |
| BR112016002970A2 (pt) | 2013-08-12 | 2017-09-12 | Tokai Pharmaceuticals Inc | biomarcadores para o tratamento de distúrbios neoplásicos que usa terapias direcionadas ao androgênio |
| US10526660B2 (en) | 2013-09-12 | 2020-01-07 | Dana-Farber Cancer Institute, Inc. | Methods for evaluating and treating Waldenstrom's macroglobulinemia |
| EP3183240A4 (en) | 2014-08-18 | 2018-06-27 | Ampio Pharmaceuticals, Inc. | Treatment of joint conditions |
| EP3310375A4 (en) | 2015-06-22 | 2019-02-20 | Ampio Pharmaceuticals, Inc. | USE OF LOW-MOLECULAR FRACTIONS OF HUMAN SERUMALBUMINE IN THE TREATMENT OF ILLNESSES |
| WO2021118924A2 (en) | 2019-12-12 | 2021-06-17 | Ting Therapeutics Llc | Compositions and methods for the prevention and treatment of hearing loss |
| CN111704546A (zh) * | 2020-06-30 | 2020-09-25 | 海南师范大学 | 一种含氧环己烷衍生物及其制备方法与应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5227508A (en) * | 1992-01-24 | 1993-07-13 | Mayo Foundation For Medical Education And Research | 3-deoxy-3-substituted analogs of phosphatidylinositol |
| WO2000000206A1 (en) * | 1998-06-26 | 2000-01-06 | Georgetown University | Inhibitors of phosphatidyl myo-inositol cycle |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4585762A (en) * | 1982-07-30 | 1986-04-29 | Fujisawa Pharmaceutical Co., Ltd. | Phospholipid derivatives, processes for use thereof and pharmaceutical composition of the same |
| JPS59187786A (ja) * | 1983-04-11 | 1984-10-24 | Meito Sangyo Kk | 酵素法リン脂質二級アルコ−ル誘導体の製法 |
| US4783402A (en) * | 1983-04-11 | 1988-11-08 | Meito Sangyo Kabushiki Kaisha | Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique |
-
2003
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- 2003-09-03 AU AU2003270087A patent/AU2003270087B2/en not_active Ceased
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- 2003-09-03 WO PCT/US2003/027607 patent/WO2004022569A1/en not_active Ceased
- 2003-09-03 JP JP2004534522A patent/JP4641796B2/ja not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5227508A (en) * | 1992-01-24 | 1993-07-13 | Mayo Foundation For Medical Education And Research | 3-deoxy-3-substituted analogs of phosphatidylinositol |
| WO2000000206A1 (en) * | 1998-06-26 | 2000-01-06 | Georgetown University | Inhibitors of phosphatidyl myo-inositol cycle |
Non-Patent Citations (1)
| Title |
|---|
| Hu et al. Tetrahedron Letters (2000) 41(39): 7415-7418 * |
Also Published As
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| US20050272708A1 (en) | 2005-12-08 |
| CA2497572A1 (en) | 2004-03-18 |
| JP4641796B2 (ja) | 2011-03-02 |
| JP2005537329A (ja) | 2005-12-08 |
| US7378403B2 (en) | 2008-05-27 |
| WO2004022569A1 (en) | 2004-03-18 |
| WO2004022569A9 (en) | 2004-06-10 |
| EP1537129B1 (en) | 2013-11-06 |
| AU2003270087A1 (en) | 2004-03-29 |
| CA2497572C (en) | 2013-05-14 |
| EP1537129A1 (en) | 2005-06-08 |
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| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |