AU2003255819A1 - Pyrimidine derivatives as modulators of chemokine receptor activity - Google Patents

Pyrimidine derivatives as modulators of chemokine receptor activity

Info

Publication number
AU2003255819A1
AU2003255819A1 AU2003255819A AU2003255819A AU2003255819A1 AU 2003255819 A1 AU2003255819 A1 AU 2003255819A1 AU 2003255819 A AU2003255819 A AU 2003255819A AU 2003255819 A AU2003255819 A AU 2003255819A AU 2003255819 A1 AU2003255819 A1 AU 2003255819A1
Authority
AU
Australia
Prior art keywords
modulators
chemokine receptor
receptor activity
pyrimidine derivatives
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003255819A
Other languages
English (en)
Inventor
Lal Lashkar Singh Cheema
Antony Ronald Cook
Mark Richard Ebden
Premji Meghani
John Steele
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0219819A external-priority patent/GB0219819D0/en
Priority claimed from GB0223287A external-priority patent/GB0223287D0/en
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of AU2003255819A1 publication Critical patent/AU2003255819A1/en
Abandoned legal-status Critical Current

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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Transplantation (AREA)
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AU2003255819A 2002-08-24 2003-08-20 Pyrimidine derivatives as modulators of chemokine receptor activity Abandoned AU2003255819A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0219819.0 2002-08-24
GB0219819A GB0219819D0 (en) 2002-08-24 2002-08-24 Novel compound
GB0223287.4 2002-10-08
GB0223287A GB0223287D0 (en) 2002-10-08 2002-10-08 Novel compound
PCT/GB2003/003632 WO2004018435A1 (en) 2002-08-24 2003-08-20 Pyrimidine derivatives as modulators of chemokine receptor activity

Publications (1)

Publication Number Publication Date
AU2003255819A1 true AU2003255819A1 (en) 2004-03-11

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003255819A Abandoned AU2003255819A1 (en) 2002-08-24 2003-08-20 Pyrimidine derivatives as modulators of chemokine receptor activity

Country Status (8)

Country Link
US (1) US7482355B2 (cg-RX-API-DMAC10.html)
EP (1) EP1539713B1 (cg-RX-API-DMAC10.html)
JP (2) JP4694963B2 (cg-RX-API-DMAC10.html)
AT (1) ATE381546T1 (cg-RX-API-DMAC10.html)
AU (1) AU2003255819A1 (cg-RX-API-DMAC10.html)
DE (1) DE60318219T2 (cg-RX-API-DMAC10.html)
ES (1) ES2295685T3 (cg-RX-API-DMAC10.html)
WO (1) WO2004018435A1 (cg-RX-API-DMAC10.html)

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US8529625B2 (en) 2003-08-22 2013-09-10 Smith & Nephew, Inc. Tissue repair and replacement
EP2311827A1 (en) * 2004-08-28 2011-04-20 AstraZeneca AB Thiopyrimidine derivative, useful as an intermediate for chemokine receptor modulators.
MX2007005857A (es) 2004-11-17 2007-10-10 Mikana Therapeutics Inc Inhibidores de cinasa.
BRPI0616630B8 (pt) * 2005-09-30 2021-05-25 Miikana Therapeutics Inc compostos de pirazol substituídos
AU2007323335A1 (en) * 2006-11-23 2008-05-29 Novartis Ag Pyrimidines and their use as CXCR2 receptor antagonists
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WO2009151910A2 (en) * 2008-05-25 2009-12-17 Wyeth Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer
CA2730477A1 (en) * 2008-07-16 2010-01-21 Astrazeneca Ab Pyrimidyl sulfonaminde derivative and its use for the treatment of chemokine mediated diseases
EP2942346B1 (en) 2009-02-17 2020-05-06 Syntrix Biosystems, Inc. Pyridinecarboxamides as cxcr2 modulators
CN102822163B (zh) 2009-12-23 2016-01-20 艾恩伍德医药品股份有限公司 Crth2调节剂
US20130259830A1 (en) 2010-07-12 2013-10-03 Ironwood Pharmaceuticals, Inc. Crth2 modulators
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