AU2003254847B2 - Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof - Google Patents

Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof Download PDF

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Publication number
AU2003254847B2
AU2003254847B2 AU2003254847A AU2003254847A AU2003254847B2 AU 2003254847 B2 AU2003254847 B2 AU 2003254847B2 AU 2003254847 A AU2003254847 A AU 2003254847A AU 2003254847 A AU2003254847 A AU 2003254847A AU 2003254847 B2 AU2003254847 B2 AU 2003254847B2
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AU
Australia
Prior art keywords
group
inhibitor
alkyl
methyl
pyrazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003254847A
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English (en)
Other versions
AU2003254847A1 (en
Inventor
Nobuhiko Fushimi
Masayuki Isaji
Toshihide Shibazaki
Kazuo Shimizu
Hirotaka Teranishi
Shigeru Yonekubo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
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Kissei Pharmaceutical Co Ltd
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Publication date
Application filed by Kissei Pharmaceutical Co Ltd filed Critical Kissei Pharmaceutical Co Ltd
Publication of AU2003254847A1 publication Critical patent/AU2003254847A1/en
Application granted granted Critical
Publication of AU2003254847B2 publication Critical patent/AU2003254847B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2003254847A 2002-08-08 2003-08-07 Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof Ceased AU2003254847B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2002/232074 2002-08-08
JP2002232074 2002-08-08
JP2002/321729 2002-11-05
JP2002321729 2002-11-05
PCT/JP2003/010048 WO2004014932A1 (ja) 2002-08-08 2003-08-07 ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体

Publications (2)

Publication Number Publication Date
AU2003254847A1 AU2003254847A1 (en) 2004-02-25
AU2003254847B2 true AU2003254847B2 (en) 2009-06-04

Family

ID=31719857

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003254847A Ceased AU2003254847B2 (en) 2002-08-08 2003-08-07 Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof

Country Status (18)

Country Link
US (2) US7375087B2 (enExample)
EP (1) EP1544208B1 (enExample)
JP (1) JP4540475B2 (enExample)
KR (1) KR100985502B1 (enExample)
AT (1) ATE469161T1 (enExample)
AU (1) AU2003254847B2 (enExample)
BR (1) BRPI0313290B1 (enExample)
CA (1) CA2494179C (enExample)
DE (1) DE60332743D1 (enExample)
ES (1) ES2345250T3 (enExample)
IL (1) IL166748A0 (enExample)
MX (1) MXPA05001549A (enExample)
NO (1) NO330456B1 (enExample)
NZ (1) NZ538117A (enExample)
PL (1) PL213095B1 (enExample)
RU (1) RU2356906C2 (enExample)
TW (1) TW200413401A (enExample)
WO (1) WO2004014932A1 (enExample)

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Also Published As

Publication number Publication date
BRPI0313290B1 (pt) 2016-12-06
US7655632B2 (en) 2010-02-02
KR100985502B1 (ko) 2010-10-05
NO330456B1 (no) 2011-04-18
AU2003254847A1 (en) 2004-02-25
DE60332743D1 (de) 2010-07-08
RU2356906C2 (ru) 2009-05-27
JP4540475B2 (ja) 2010-09-08
TW200413401A (en) 2004-08-01
JPWO2004014932A1 (ja) 2005-12-02
EP1544208A1 (en) 2005-06-22
BR0313290A (pt) 2005-07-05
TWI341843B (enExample) 2011-05-11
ES2345250T3 (es) 2010-09-20
EP1544208B1 (en) 2010-05-26
US20080312153A1 (en) 2008-12-18
PL375473A1 (en) 2005-11-28
EP1544208A4 (en) 2007-05-02
US7375087B2 (en) 2008-05-20
IL166748A0 (en) 2006-01-15
CA2494179A1 (en) 2004-02-19
KR20050059067A (ko) 2005-06-17
CA2494179C (en) 2012-04-24
RU2005106259A (ru) 2005-08-27
HK1082743A1 (zh) 2006-06-16
US20060166899A1 (en) 2006-07-27
PL213095B1 (pl) 2013-01-31
NO20051209L (no) 2005-04-15
ATE469161T1 (de) 2010-06-15
MXPA05001549A (es) 2005-05-05
WO2004014932A1 (ja) 2004-02-19
NZ538117A (en) 2007-01-26

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