AU2003251651B2 - Polymorphis of a known thiophenecarboxylic acid dodecahydrocyclopenta [a] phenanthrenyl ester - Google Patents

Polymorphis of a known thiophenecarboxylic acid dodecahydrocyclopenta [a] phenanthrenyl ester Download PDF

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Publication number
AU2003251651B2
AU2003251651B2 AU2003251651A AU2003251651A AU2003251651B2 AU 2003251651 B2 AU2003251651 B2 AU 2003251651B2 AU 2003251651 A AU2003251651 A AU 2003251651A AU 2003251651 A AU2003251651 A AU 2003251651A AU 2003251651 B2 AU2003251651 B2 AU 2003251651B2
Authority
AU
Australia
Prior art keywords
crystal form
compound
formula
inflammatory
crystal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003251651A
Other languages
English (en)
Other versions
AU2003251651A1 (en
Inventor
Guido Jordine
Michael Mutz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU2003251651A1 publication Critical patent/AU2003251651A1/en
Priority to AU2007202962A priority Critical patent/AU2007202962A1/en
Application granted granted Critical
Publication of AU2003251651B2 publication Critical patent/AU2003251651B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
AU2003251651A 2002-07-29 2003-07-28 Polymorphis of a known thiophenecarboxylic acid dodecahydrocyclopenta [a] phenanthrenyl ester Ceased AU2003251651B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2007202962A AU2007202962A1 (en) 2002-07-29 2007-06-27 Polymorphis of a known thiophenecarboxylic acid dodecahydrocyclopenta (A) phenanthrenyl ester

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0217504.0A GB0217504D0 (en) 2002-07-29 2002-07-29 Organic compounds
GB0217504.0 2002-07-29
PCT/EP2003/008314 WO2004013156A1 (en) 2002-07-29 2003-07-28 Polymorphis of a known thiophenecarboxylic acid dodecahydrocyclopenta (a) phenanthrenyl ester

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2007202962A Division AU2007202962A1 (en) 2002-07-29 2007-06-27 Polymorphis of a known thiophenecarboxylic acid dodecahydrocyclopenta (A) phenanthrenyl ester

Publications (2)

Publication Number Publication Date
AU2003251651A1 AU2003251651A1 (en) 2004-02-23
AU2003251651B2 true AU2003251651B2 (en) 2007-07-12

Family

ID=9941275

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003251651A Ceased AU2003251651B2 (en) 2002-07-29 2003-07-28 Polymorphis of a known thiophenecarboxylic acid dodecahydrocyclopenta [a] phenanthrenyl ester

Country Status (30)

Country Link
US (1) US7683048B2 (enExample)
EP (2) EP1554303B1 (enExample)
JP (1) JP2006501207A (enExample)
KR (1) KR100688371B1 (enExample)
CN (1) CN1305892C (enExample)
AR (1) AR040692A1 (enExample)
AT (1) ATE349459T1 (enExample)
AU (1) AU2003251651B2 (enExample)
BR (1) BR0313044A (enExample)
CA (1) CA2493330C (enExample)
CY (1) CY1106406T1 (enExample)
DE (1) DE60310747T2 (enExample)
DK (1) DK1554303T3 (enExample)
EC (1) ECSP055579A (enExample)
ES (1) ES2279970T3 (enExample)
GB (1) GB0217504D0 (enExample)
HK (1) HK1080484B (enExample)
IL (2) IL166287A0 (enExample)
MX (1) MXPA05001173A (enExample)
MY (1) MY136407A (enExample)
NO (1) NO20050806L (enExample)
NZ (2) NZ549713A (enExample)
PE (1) PE20040722A1 (enExample)
PL (1) PL209409B1 (enExample)
PT (1) PT1554303E (enExample)
RU (2) RU2348646C1 (enExample)
SI (1) SI1554303T1 (enExample)
TW (1) TWI309164B (enExample)
WO (1) WO2004013156A1 (enExample)
ZA (1) ZA200500370B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2417826A1 (en) 2000-08-05 2002-02-14 Glaxo Group Limited 17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derivative as anti-inflammatory agents
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6858596B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
AR033290A1 (es) 2001-04-30 2003-12-10 Glaxo Group Ltd Derivados antiinflamatorios de androstano
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
GB0523654D0 (en) * 2005-11-21 2005-12-28 Novartis Ag Organic compounds
GB0523656D0 (en) * 2005-11-21 2005-12-28 Novartis Ag Organic compounds
GB0603783D0 (en) * 2006-02-24 2006-04-05 Novartis Ag Organic compounds
CN103463084A (zh) * 2008-03-14 2013-12-25 大塚制药株式会社 制剂组合物在制备治疗以mmp-2及/或mmp-9为起因的肺气肿的药物中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8389101A (en) * 2000-06-28 2002-01-08 Novartis Ag Organic compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU550939A1 (ru) * 1975-05-19 1994-07-15 Институт химии древесины АН ЛатвССР 1,2,3,4,4а,4в,5,6,10,10а -декагидро -6- хлорацетоксиметил -1,4а-диметил -7- (1-метилэтил) -1- фенантренкарбоновая кислота или ее соли
JPH08291073A (ja) * 1995-04-22 1996-11-05 Kissei Pharmaceut Co Ltd 医薬品組成物及びその製造方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8389101A (en) * 2000-06-28 2002-01-08 Novartis Ag Organic compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Haleblian, J. et al. J. Pharmaceutical Sci.1969 58(8) 911-929 *

Also Published As

Publication number Publication date
EP1554303B1 (en) 2006-12-27
CY1106406T1 (el) 2011-10-12
NZ537868A (en) 2006-11-30
DE60310747D1 (en) 2007-02-08
US7683048B2 (en) 2010-03-23
PE20040722A1 (es) 2004-11-29
DK1554303T3 (da) 2007-04-30
ECSP055579A (es) 2005-04-18
TWI309164B (en) 2009-05-01
EP1554303A1 (en) 2005-07-20
HK1080484A1 (en) 2006-04-28
GB0217504D0 (en) 2002-09-04
EP1676854A1 (en) 2006-07-05
MXPA05001173A (es) 2005-05-16
PL209409B1 (pl) 2011-08-31
IL184848A0 (en) 2007-12-03
NO20050806L (no) 2005-02-15
NZ549713A (en) 2008-04-30
MY136407A (en) 2008-09-30
AR040692A1 (es) 2005-04-13
AU2003251651A1 (en) 2004-02-23
RU2348646C1 (ru) 2009-03-10
CN1305892C (zh) 2007-03-21
PL373140A1 (en) 2005-08-22
CA2493330A1 (en) 2004-02-12
IL166287A0 (en) 2006-01-15
BR0313044A (pt) 2005-06-14
PT1554303E (pt) 2007-03-30
US20060166954A1 (en) 2006-07-27
JP2006501207A (ja) 2006-01-12
ATE349459T1 (de) 2007-01-15
RU2007143025A (ru) 2009-01-20
KR100688371B1 (ko) 2007-03-02
ZA200500370B (en) 2006-07-26
KR20050033632A (ko) 2005-04-12
RU2005105688A (ru) 2005-10-10
WO2004013156A1 (en) 2004-02-12
ES2279970T3 (es) 2007-09-01
SI1554303T1 (sl) 2007-06-30
RU2330043C2 (ru) 2008-07-27
CN1671731A (zh) 2005-09-21
CA2493330C (en) 2011-08-23
DE60310747T2 (de) 2007-10-11
HK1080484B (en) 2007-08-03
TW200401633A (en) 2004-02-01

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired