AU2002252227A1 - Heterocyclic derivatives for the treatment of cancer and other proliferative diseases - Google Patents

Heterocyclic derivatives for the treatment of cancer and other proliferative diseases

Info

Publication number
AU2002252227A1
AU2002252227A1 AU2002252227A AU2002252227A AU2002252227A1 AU 2002252227 A1 AU2002252227 A1 AU 2002252227A1 AU 2002252227 A AU2002252227 A AU 2002252227A AU 2002252227 A AU2002252227 A AU 2002252227A AU 2002252227 A1 AU2002252227 A1 AU 2002252227A1
Authority
AU
Australia
Prior art keywords
cancer
treatment
proliferative diseases
heterocyclic derivatives
heterocyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002252227A
Other languages
English (en)
Inventor
Hussein A. Al-Shamma
Andrea Fanjul
Jason B. Ibarra
Magnus Pfahl
David P. M. Pleynet
Lyle W. Spruce
Catherine Tachdjian
Torsten R. Wiemann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte San Diego Inc
Original Assignee
Maxia Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maxia Pharmaceuticals Inc filed Critical Maxia Pharmaceuticals Inc
Publication of AU2002252227A1 publication Critical patent/AU2002252227A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2002252227A 2001-03-07 2002-03-07 Heterocyclic derivatives for the treatment of cancer and other proliferative diseases Abandoned AU2002252227A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27475101P 2001-03-07 2001-03-07
US60/274,751 2001-03-07
PCT/US2002/007001 WO2002072009A2 (en) 2001-03-07 2002-03-07 Heterocyclic derivatives for the treatment of cancer and other proliferative diseases

Publications (1)

Publication Number Publication Date
AU2002252227A1 true AU2002252227A1 (en) 2002-09-24

Family

ID=23049469

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002252227A Abandoned AU2002252227A1 (en) 2001-03-07 2002-03-07 Heterocyclic derivatives for the treatment of cancer and other proliferative diseases

Country Status (12)

Country Link
US (1) US7153875B2 (cg-RX-API-DMAC7.html)
EP (1) EP1385465A4 (cg-RX-API-DMAC7.html)
JP (1) JP2005506290A (cg-RX-API-DMAC7.html)
AU (1) AU2002252227A1 (cg-RX-API-DMAC7.html)
BR (1) BR0207846A (cg-RX-API-DMAC7.html)
CA (1) CA2440184A1 (cg-RX-API-DMAC7.html)
EA (1) EA200300982A1 (cg-RX-API-DMAC7.html)
IL (1) IL157740A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA03008117A (cg-RX-API-DMAC7.html)
NO (1) NO20033883L (cg-RX-API-DMAC7.html)
PL (1) PL373912A1 (cg-RX-API-DMAC7.html)
WO (1) WO2002072009A2 (cg-RX-API-DMAC7.html)

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JP2004523571A (ja) 2001-03-08 2004-08-05 マキシア・ファーマシューティカルズ・インコーポレイテッド Rxr活性化分子
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CA2468745A1 (en) 2001-11-30 2003-06-12 The Burnham Institute Induction of apoptosis in cancer cells
US7196108B2 (en) * 2002-03-08 2007-03-27 Incyte San Diego Inc. Bicyclic heterocycles for the treatment of diabetes and other diseases
US7102000B2 (en) * 2002-03-08 2006-09-05 Incyte San Diego Inc. Heterocyclic amide derivatives for the treatment of diabetes and other diseases
US7714139B2 (en) * 2003-03-27 2010-05-11 Lankenau Institute For Medcial Research IDO inhibitors and methods of use
FR2856401B1 (fr) * 2003-06-20 2010-02-12 Galderma Res & Dev Nouveaux composes modulateurs des recepteurs de type ppargamma et leur utilisation dans des compositions cosmetiques ou pharmaceutiques
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KR100814109B1 (ko) 2006-01-09 2008-03-14 한국생명공학연구원 로다닌 유도체, 이의 제조방법 및 이를 유효성분으로함유하는 약학적 조성물
CL2007000995A1 (es) * 2006-04-11 2008-06-27 Smithkline Beecham Corp Compuestos derivados de tiazolidinadiona; composicion farmaceutica; y uso para tratar uno o mas estados de enfermedad seleccionada entre trastornos autoinmunes, enfermedad inflamatoria, cardiovascular y neurodegenerativa entre otras.
US20080255115A1 (en) * 2007-04-11 2008-10-16 Michael Gerard Darcy Thiazolidinedione derivatives as pi3 kinase inhibitors
PE20090288A1 (es) * 2007-05-10 2009-04-03 Smithkline Beecham Corp Derivados de quinoxalina como inhibidores de la pi3 quinasa
PE20090717A1 (es) * 2007-05-18 2009-07-18 Smithkline Beecham Corp Derivados de quinolina como inhibidores de la pi3 quinasa
EP2222638A2 (en) * 2007-11-21 2010-09-01 Decode Genetics EHF Biaryl pde4 inhibitors for treating inflammation
JP2011504505A (ja) 2007-11-21 2011-02-10 デコード ジェネティクス イーエイチエフ 肺および心血管障害を治療するためのビアリールpde4抑制剤
CN102558088A (zh) * 2010-12-31 2012-07-11 中国科学院上海药物研究所 联苯亚甲基-2-硫代-4-噻唑酮类化合物及其制备方法和用途
US20250066347A1 (en) * 2021-12-21 2025-02-27 Medific, Inc. Substituted thiazolidinedione derivative compound, and pharmaceutical composition for preventing or treating cancer, comprising same
KR102922092B1 (ko) * 2021-12-21 2026-02-03 주식회사 메디픽바이오 치환된 티아졸리딘디온 유도체 화합물 및 이를 포함하는 암의 예방 또는 치료용 약학적 조성물
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Also Published As

Publication number Publication date
WO2002072009A2 (en) 2002-09-19
JP2005506290A (ja) 2005-03-03
US20020143182A1 (en) 2002-10-03
EA200300982A1 (ru) 2004-12-30
MXPA03008117A (es) 2004-11-12
IL157740A0 (en) 2004-03-28
NO20033883D0 (no) 2003-09-02
WO2002072009A3 (en) 2003-10-16
CA2440184A1 (en) 2002-09-19
EP1385465A4 (en) 2005-09-07
PL373912A1 (en) 2005-09-19
EP1385465A2 (en) 2004-02-04
US7153875B2 (en) 2006-12-26
NO20033883L (no) 2003-11-05
BR0207846A (pt) 2005-09-13

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