AU2001274084A1 - The non-mevalonate isoprenoid pathway - Google Patents

The non-mevalonate isoprenoid pathway

Info

Publication number
AU2001274084A1
AU2001274084A1 AU2001274084A AU7408401A AU2001274084A1 AU 2001274084 A1 AU2001274084 A1 AU 2001274084A1 AU 2001274084 A AU2001274084 A AU 2001274084A AU 7408401 A AU7408401 A AU 7408401A AU 2001274084 A1 AU2001274084 A1 AU 2001274084A1
Authority
AU
Australia
Prior art keywords
variants
biosynthesis
isoprenoids
inhibitors
encoding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001274084A
Other languages
English (en)
Inventor
Petra Adam
Adelbert Bacher
Wolfgang Eisenreich
Monika Fellermeier
Stefan Hecht
Felix Rohdich
Christoph A. Schuhr
Juraithip Wungsintaweekul
Meinhart H. Zenk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU2001274084A1 publication Critical patent/AU2001274084A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
AU2001274084A 2000-06-05 2001-06-01 The non-mevalonate isoprenoid pathway Abandoned AU2001274084A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10027821A DE10027821A1 (de) 2000-06-05 2000-06-05 Der Mevalonat-unabhängige Isoprenoidbiosyntheseweg
DE10027821 2000-06-05
PCT/EP2001/006255 WO2001094561A2 (en) 2000-06-05 2001-06-01 The non-mevalonate isoprenoid pathway

Publications (1)

Publication Number Publication Date
AU2001274084A1 true AU2001274084A1 (en) 2001-12-17

Family

ID=7644765

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001274084A Abandoned AU2001274084A1 (en) 2000-06-05 2001-06-01 The non-mevalonate isoprenoid pathway

Country Status (6)

Country Link
US (2) US7288367B2 (de)
EP (1) EP1287145B1 (de)
AT (1) ATE415479T1 (de)
AU (1) AU2001274084A1 (de)
DE (2) DE10027821A1 (de)
WO (1) WO2001094561A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60036477T2 (de) 1999-08-04 2008-06-12 Bacher, Adelbert, Prof. Dr.med. Dr.rer.nat. Isoprenoid biosynthese
DE10027821A1 (de) 2000-06-05 2001-12-06 Adelbert Bacher Der Mevalonat-unabhängige Isoprenoidbiosyntheseweg
US6660507B2 (en) * 2000-09-01 2003-12-09 E. I. Du Pont De Nemours And Company Genes involved in isoprenoid compound production
DE10201458A1 (de) * 2001-04-11 2002-10-17 Adelbert Bacher Intermediate und Enzyme des Mevalonat-unabhängigen Isoprenoidbiosyntheseweg
ATE371729T1 (de) * 2001-05-15 2007-09-15 Adelbert Bacher Kristallstruktur der 2c-methyl-d-erythritol-2,4- cyclodiphosphat-synthase
PT1408984E (pt) 2001-07-20 2008-12-26 Bioagency Ag Compostos organofosforosos para activar células t gama/delta
BR122021005304B1 (pt) 2010-06-02 2022-02-22 Evolva, Inc Hospedeiro recombinante que compreende genes recombinantes para produção de esteviol ou glicosídeo de esteviol, ácido nucleico, método para produzir esteviol, glicosídeo de esteviol ou composição de glicosídeo de esteviol e método para sintetizar esteviol ou glicosídeo de esteviol
CN103732753B (zh) 2011-08-08 2018-03-30 埃沃尔瓦公司 甜菊醇糖苷类的重组生产
CA3171770A1 (en) 2013-02-06 2014-08-14 Evolva Sa Methods for improved production of rebaudioside d and rebaudioside m
EP2954061B1 (de) 2013-02-11 2023-11-22 Evolva SA Effiziente herstellung von steviolglycosiden in rekombinanten wirtszellen
MX2017001859A (es) 2014-08-11 2017-04-11 Evolva Sa Produccion de glicosidos de esteviol en hospederos recombinantes.
SG11201701677UA (en) 2014-09-09 2017-04-27 Evolva Sa Production of steviol glycosides in recombinant hosts
CA2973674A1 (en) 2015-01-30 2016-08-04 Evolva Sa Production of steviol glycosides in recombinant hosts
US10604743B2 (en) 2015-03-16 2020-03-31 Dsm Ip Assets B.V. UDP-glycosyltransferases
WO2017025362A1 (en) 2015-08-07 2017-02-16 Evolva Sa Production of steviol glycosides in recombinant hosts
CA3020671A1 (en) 2016-04-13 2017-10-19 Evolva Sa Production of steviol glycosides in recombinant hosts
EP3458599A1 (de) 2016-05-16 2019-03-27 Evolva SA Herstellung von steviolglycosiden in rekombinanten wirten
EP3535406A1 (de) 2016-11-07 2019-09-11 Evolva SA Herstellung von steviolglycosiden in rekombinanten wirten

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3587718T2 (de) 1984-03-06 1994-08-04 Mgi Pharma Inc Herbizide Resistenz in Pflanzen.
GB9315751D0 (en) 1993-07-30 1993-09-15 Zeneca Ltd Dna,dna constructs,cells and plants derived therefrom
US5885782A (en) 1994-09-13 1999-03-23 Nce Pharmaceuticals, Inc. Synthetic antibiotics
US6107071A (en) 1996-09-24 2000-08-22 Smithkline Beecham Corporation Histidinol dehydrogenase
US5858367A (en) 1997-03-27 1999-01-12 Case Western Reserve University Methods for screening for antimicrobials utilizing AarC and compositions thereof
WO1999011757A1 (en) 1997-09-02 1999-03-11 Washington State University Research Foundation NUCLEIC AND AMINO ACID SEQUENCES FOR A NOVEL TRANSKETOLASE FROM $i (MENTHA PIPERITA)
DE19752700A1 (de) 1997-11-28 1999-06-02 Hoechst Schering Agrevo Gmbh 1-Desoxy-D-xylulose-5-phosphat Synthase, Verfahren zur Identifizierung von Effektoren der 1-Desoxy-D-xylulose-5-phosphat Synthase und Effektoren der 1-Desoxy-D-xylulose-5-phosphat Synthase
CA2328157A1 (en) 1998-04-14 1999-10-21 Jomaa Hassan Method for identifying chemical active agents and active agents for inhibiting the 1-desoxy-d-xylulose-5-phosphate biosynthetic pathway
WO1999058649A1 (en) * 1998-05-13 1999-11-18 University Of Maryland Methods of modifying the production of isopentenyl pyrophosphate, dimethylallyl pyrophosphate and/or isoprenoids
SK3922001A3 (en) 1998-09-22 2001-09-11 Jomaa Pharmaka Gmbh Genes of the 1-desoxy-d-xylulose biosynthetic pathway
JP2002532101A (ja) * 1998-12-14 2002-10-02 バッハー，アーデルバート テルペノイド類生合成阻害剤のためのスクリーニング
JP2003500073A (ja) * 1999-05-21 2003-01-07 ヨマー、ファルマカ、ゲゼルシャフト、ミット、ベシュレンクテル、ハフツング イソプレノイドの濃度を変更するためのデオキシ−ｄ−キシルロースホスフェート生合成経路の遺伝子の使用
DE60036477T2 (de) 1999-08-04 2008-06-12 Bacher, Adelbert, Prof. Dr.med. Dr.rer.nat. Isoprenoid biosynthese
DE10021688A1 (de) 2000-05-05 2001-11-15 Hassan Jomaa Gene des 1-Desoxy-D-xylulose-Biosynthesewegs
DE10027821A1 (de) 2000-06-05 2001-12-06 Adelbert Bacher Der Mevalonat-unabhängige Isoprenoidbiosyntheseweg
AU2001290522B2 (en) 2000-08-07 2006-11-30 Monsanto Technology Llc Methyl-D-erythritol phosphate pathway genes
DE10201458A1 (de) 2001-04-11 2002-10-17 Adelbert Bacher Intermediate und Enzyme des Mevalonat-unabhängigen Isoprenoidbiosyntheseweg
ATE371729T1 (de) 2001-05-15 2007-09-15 Adelbert Bacher Kristallstruktur der 2c-methyl-d-erythritol-2,4- cyclodiphosphat-synthase
AU2002322265A1 (en) 2001-06-18 2003-01-02 Structural Genomix Crystals and structure of 2c-methyl-d-erythritol 2,4-cyclodiphosphate synthase mecps

Also Published As

Publication number Publication date
WO2001094561A2 (en) 2001-12-13
EP1287145A2 (de) 2003-03-05
US7288367B2 (en) 2007-10-30
DE10027821A1 (de) 2001-12-06
ATE415479T1 (de) 2008-12-15
US20040072142A1 (en) 2004-04-15
DE60136701D1 (de) 2009-01-08
WO2001094561A3 (en) 2002-05-30
EP1287145B1 (de) 2008-11-26
US20090199313A1 (en) 2009-08-06

Similar Documents

Publication Publication Date Title
AU2001274084A1 (en) The non-mevalonate isoprenoid pathway
Sharkey et al. Photometric method for routine determination of k cat and carbamylation of rubisco
Hanson et al. One-carbon metabolism in higher plants
Ziegler Hydrogen isotope fractionation in plant tissues
Berger et al. Medicago truncatula Phytoglobin 1.1 controls symbiotic nodulation and nitrogen fixation via the regulation of nitric oxide concentration
Hirai et al. Global expression profiling of sulfur‐starved Arabidopsis by DNA macroarray reveals the role of O‐acetyl‐l‐serine as a general regulator of gene expression in response to sulfur nutrition
Anderson et al. Abiotic stress alters transcript profiles and activity of glutathione S‐transferase, glutathione peroxidase, and glutathione reductase in Euphorbia esula
Blackwell et al. Inhibition of photosynthesis in barley with decreased levels of chloroplastic glutamine synthetase activity
Meinzer et al. Nitrogen stress reduces the efficiency of the C4CO2 concentrating system, and therefore quantum yield, in Saccharum (sugarcane) species
Bowes et al. C4 mechanisms in aquatic angiosperms: comparisons with terrestrial C4 systems
Mengistu et al. psbA mutation (valine219 to isoleucine) in Poa annua resistant to metribuzin and diuron
BR9710751A (pt) ácido nucléico, vetor de dna, célula compreendendo um vetor de dna, semente, proteìna hppd, método para identificar inibidores de herbecidas/hppd, método para identificar variantes de hppd resistentes a herbicida, proteìna hppd variante, método para prover a uma planta resistência à herbicida, método para controle de ervas daninhas
Gutiérrez-Barranquero et al. Pseudomonas syringae pv. syringae associated with mango trees, a particular pathogen within the “hodgepodge” of the Pseudomonas syringae complex
AU2002215087A1 (en) Herbicide-tolerant plants through bypassing metabolic pathway
Durner et al. Acetolactate synthase from barley (Hordeum vulgare L.): purification and partial characterization
WO2000032761A8 (en) Ethylene-response-factor1 (erf1) in plants
TR199701492T1 (xx) Hidroksi-fenil piruvat dioksijenaz�n bir geninin DNA sekans�
RAVEN et al. The influence of natural and experimental high O2 concentrations on O2‐evolving phototrophs
CN107426979B (zh) 具有增加的除草剂耐受性的植物
DE60036477D1 (en) Isoprenoid biosynthese
Nadler‐Hassar et al. Natural tolerance of Cuscuta campestris to herbicides inhibiting amino acid biosynthesis
Sangwan et al. Interspecific variation in physiological and metabolic responses of five species of Cymbopogon to water stress
Dakora et al. Elevated CO2 stimulates associative N2 fixation in a C3 plant of the Chesapeake Bay wetland
DiMario et al. Lack of leaf carbonic anhydrase activity eliminates the C4 carbon‐concentrating mechanism requiring direct diffusion of CO2 into bundle sheath cells
Burandt et al. Genotypical differences intotal sulfur contents and cysteine desulfhydrase activities in Brassica napus L'