AU2001255196A1 - Compositions and methods for enhancing immunogenicity of antigens - Google Patents
Compositions and methods for enhancing immunogenicity of antigensInfo
- Publication number
- AU2001255196A1 AU2001255196A1 AU2001255196A AU5519601A AU2001255196A1 AU 2001255196 A1 AU2001255196 A1 AU 2001255196A1 AU 2001255196 A AU2001255196 A AU 2001255196A AU 5519601 A AU5519601 A AU 5519601A AU 2001255196 A1 AU2001255196 A1 AU 2001255196A1
- Authority
- AU
- Australia
- Prior art keywords
- antigens
- compositions
- methods
- enhancing immunogenicity
- immunogenicity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 230000002708 enhancing effect Effects 0.000 title 1
- 230000005847 immunogenicity Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0208—Specific bacteria not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/35—Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09537642 | 2000-03-29 | ||
US09/537,642 US6855320B2 (en) | 2000-03-29 | 2000-03-29 | Fusion of non-hemolytic, truncated form of listeriolysin O to antigens to enhance immunogenicity |
US09735450 | 2000-12-13 | ||
US09/735,450 US6767542B2 (en) | 2000-03-29 | 2000-12-13 | Compositions and methods for enhancing immunogenicity of antigens |
PCT/US2001/009736 WO2001072329A1 (fr) | 2000-03-29 | 2001-03-26 | Compositions et procedes renforçant l'immunogenicite d'antigenes |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001255196A1 true AU2001255196A1 (en) | 2001-10-08 |
Family
ID=27065568
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001255196A Abandoned AU2001255196A1 (en) | 2000-03-29 | 2001-03-26 | Compositions and methods for enhancing immunogenicity of antigens |
Country Status (7)
Country | Link |
---|---|
US (3) | US7635479B2 (fr) |
EP (1) | EP1303299B1 (fr) |
JP (1) | JP2004500405A (fr) |
AU (1) | AU2001255196A1 (fr) |
CA (1) | CA2404164A1 (fr) |
IL (1) | IL151942A0 (fr) |
WO (1) | WO2001072329A1 (fr) |
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US7662396B2 (en) | 2001-03-26 | 2010-02-16 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
US7794729B2 (en) | 1994-11-08 | 2010-09-14 | The Trustees Of The University Of Pennsylvania | Methods and compositions for immunotherapy of cancer |
US8791237B2 (en) | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
US6051237A (en) * | 1994-11-08 | 2000-04-18 | The Trustees Of The University Of Pennsylvania | Specific immunotherapy of cancer using a live recombinant bacterial vaccine vector |
US20070264279A1 (en) * | 1994-11-08 | 2007-11-15 | Claudia Gravekamp | Compositions and methods comprising a MAGE-b antigen |
US20080286228A1 (en) * | 1995-10-20 | 2008-11-20 | Tarantolo Stefano R | Compositions and methods for enhancing immune responses mediated by antigen-presenting cells |
US9012141B2 (en) | 2000-03-27 | 2015-04-21 | Advaxis, Inc. | Compositions and methods comprising KLK3 of FOLH1 antigen |
CA2404164A1 (fr) | 2000-03-29 | 2001-10-04 | The Trustees Of The University Of Pennsylvania | Compositions et procedes renforcant l'immunogenicite d'antigenes |
US8771702B2 (en) * | 2001-03-26 | 2014-07-08 | The Trustees Of The University Of Pennsylvania | Non-hemolytic LLO fusion proteins and methods of utilizing same |
US7700344B2 (en) | 2001-03-26 | 2010-04-20 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
US7695725B2 (en) | 2003-02-06 | 2010-04-13 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
KR101192652B1 (ko) | 2003-02-06 | 2012-10-19 | 앤저 테라퓨틱스 인코퍼레이티드 | 비포식 세포로의 침투가 약화된 리스테리아, 리스테리아를 포함하는 백신, 및 그것의 사용방법 |
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US8906664B2 (en) | 2004-08-13 | 2014-12-09 | The Trustees Of The University Of Pennsylvania | Methods for constructing antibiotic resistance free vaccines |
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US7855064B2 (en) | 2004-08-13 | 2010-12-21 | The Trustees Of The University Of Pennsylvania | Antibiotic resistance free vaccines and methods for constructing and using same |
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US6099848A (en) | 1997-11-18 | 2000-08-08 | The Trustees Of The University Of Pennsylvania | Immunogenic compositions comprising DAL/DAT double-mutant, auxotrophic, attenuated strains of Listeria and their methods of use |
US6306404B1 (en) * | 1998-07-14 | 2001-10-23 | American Cyanamid Company | Adjuvant and vaccine compositions containing monophosphoryl lipid A |
US6355320B1 (en) * | 1998-10-21 | 2002-03-12 | Nomacorc, Llc | Synthetic closure and manufacturing process thereof |
US6818002B2 (en) * | 1999-02-02 | 2004-11-16 | Samuel Shiber | Vessel cleaner and barrier |
DE19949594A1 (de) | 1999-10-14 | 2001-04-26 | Deutsches Krebsforsch | Rekombinante attenuierte Listerien zur Immuntherapie |
CA2404164A1 (fr) * | 2000-03-29 | 2001-10-04 | The Trustees Of The University Of Pennsylvania | Compositions et procedes renforcant l'immunogenicite d'antigenes |
US6855320B2 (en) * | 2000-03-29 | 2005-02-15 | The Trustees Of The University Of Pennsylvania | Fusion of non-hemolytic, truncated form of listeriolysin O to antigens to enhance immunogenicity |
TW512968U (en) * | 2000-12-12 | 2002-12-01 | Delta Electronics Inc | Winding tube of transformer |
US7700344B2 (en) * | 2001-03-26 | 2010-04-20 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
WO2003008537A2 (fr) * | 2001-04-06 | 2003-01-30 | Mannkind Corporation | Sequences d'epitope |
WO2003015716A2 (fr) | 2001-08-13 | 2003-02-27 | Ige Therapeutics, Inc. | Vaccins d'immunoglobuline e et leurs procedes d'utilisation |
EP1480548A4 (fr) * | 2002-02-06 | 2006-02-01 | Univ Johns Hopkins Med | Procedes et compositions de ciblage de reponse immunitaire systemique contre un organe ou un tissu specifique |
US7425449B2 (en) | 2002-04-30 | 2008-09-16 | The Regents Of The University Of California | Site specific Listeria integration vectors and methods for using the same |
WO2004006837A2 (fr) | 2002-07-12 | 2004-01-22 | The Johns Hopkins University | Vaccins a la mesotheline et systemes de modele |
CA2512812A1 (fr) | 2003-01-09 | 2004-07-29 | The Trustees Of The University Of Pennsylvania | Compositions, methodes et trousses renforcant l'immunogenecite d'un vecteur de vaccin bacterien |
KR101192652B1 (ko) * | 2003-02-06 | 2012-10-19 | 앤저 테라퓨틱스 인코퍼레이티드 | 비포식 세포로의 침투가 약화된 리스테리아, 리스테리아를 포함하는 백신, 및 그것의 사용방법 |
US8906664B2 (en) * | 2004-08-13 | 2014-12-09 | The Trustees Of The University Of Pennsylvania | Methods for constructing antibiotic resistance free vaccines |
US20060121053A1 (en) * | 2004-10-18 | 2006-06-08 | Pamela Sweeney | High cell density process for growth of Listeria |
BRPI0518984A2 (pt) * | 2004-12-10 | 2008-12-16 | Univ Emory | anÁlogos de nucleosÍdeo de ciclobutil substituÍdos em 2' e 3' para tratamento de infecÇÕes virais e proliferaÇço celular anormal |
WO2007061848A2 (fr) | 2005-11-17 | 2007-05-31 | The Trustees Of The University Of Pennsylvania | Procedes pour la production, la culture, et la conservation de vecteurs vaccinaux de listeria |
WO2008008311A1 (fr) * | 2006-07-10 | 2008-01-17 | The Trustees Of The University Of Pennsylvania | Méthode d'administration de vaccins anti-tumoraux |
-
2001
- 2001-03-26 CA CA002404164A patent/CA2404164A1/fr not_active Abandoned
- 2001-03-26 AU AU2001255196A patent/AU2001255196A1/en not_active Abandoned
- 2001-03-26 IL IL15194201A patent/IL151942A0/xx unknown
- 2001-03-26 JP JP2001570290A patent/JP2004500405A/ja active Pending
- 2001-03-26 EP EP01928324A patent/EP1303299B1/fr not_active Expired - Lifetime
- 2001-03-26 US US10/239,703 patent/US7635479B2/en not_active Expired - Fee Related
- 2001-03-26 WO PCT/US2001/009736 patent/WO2001072329A1/fr active Application Filing
-
2004
- 2004-04-30 US US10/835,662 patent/US7588930B2/en not_active Expired - Lifetime
-
2006
- 2006-03-16 US US11/376,572 patent/US7655238B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US20060204516A1 (en) | 2006-09-14 |
JP2004500405A (ja) | 2004-01-08 |
US20050118184A1 (en) | 2005-06-02 |
IL151942A0 (en) | 2003-04-10 |
US7655238B2 (en) | 2010-02-02 |
CA2404164A1 (fr) | 2001-10-04 |
EP1303299B1 (fr) | 2010-07-28 |
US7635479B2 (en) | 2009-12-22 |
EP1303299A1 (fr) | 2003-04-23 |
US20070003567A1 (en) | 2007-01-04 |
EP1303299A4 (fr) | 2005-01-26 |
WO2001072329A1 (fr) | 2001-10-04 |
US7588930B2 (en) | 2009-09-15 |
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