AU2001255196A1 - Compositions and methods for enhancing immunogenicity of antigens - Google Patents

Compositions and methods for enhancing immunogenicity of antigens

Info

Publication number
AU2001255196A1
AU2001255196A1 AU2001255196A AU5519601A AU2001255196A1 AU 2001255196 A1 AU2001255196 A1 AU 2001255196A1 AU 2001255196 A AU2001255196 A AU 2001255196A AU 5519601 A AU5519601 A AU 5519601A AU 2001255196 A1 AU2001255196 A1 AU 2001255196A1
Authority
AU
Australia
Prior art keywords
antigens
compositions
methods
enhancing immunogenicity
immunogenicity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001255196A
Other languages
English (en)
Inventor
George Raymond Gunn Iii
Yvonne Paterson
Christian Peters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
Original Assignee
University of Pennsylvania Penn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/537,642 external-priority patent/US6855320B2/en
Application filed by University of Pennsylvania Penn filed Critical University of Pennsylvania Penn
Publication of AU2001255196A1 publication Critical patent/AU2001255196A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0208Specific bacteria not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/35Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2001255196A 2000-03-29 2001-03-26 Compositions and methods for enhancing immunogenicity of antigens Abandoned AU2001255196A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09537642 2000-03-29
US09/537,642 US6855320B2 (en) 2000-03-29 2000-03-29 Fusion of non-hemolytic, truncated form of listeriolysin O to antigens to enhance immunogenicity
US09735450 2000-12-13
US09/735,450 US6767542B2 (en) 2000-03-29 2000-12-13 Compositions and methods for enhancing immunogenicity of antigens
PCT/US2001/009736 WO2001072329A1 (fr) 2000-03-29 2001-03-26 Compositions et procedes renforçant l'immunogenicite d'antigenes

Publications (1)

Publication Number Publication Date
AU2001255196A1 true AU2001255196A1 (en) 2001-10-08

Family

ID=27065568

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001255196A Abandoned AU2001255196A1 (en) 2000-03-29 2001-03-26 Compositions and methods for enhancing immunogenicity of antigens

Country Status (7)

Country Link
US (3) US7635479B2 (fr)
EP (1) EP1303299B1 (fr)
JP (1) JP2004500405A (fr)
AU (1) AU2001255196A1 (fr)
CA (1) CA2404164A1 (fr)
IL (1) IL151942A0 (fr)
WO (1) WO2001072329A1 (fr)

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EP1480548A4 (fr) * 2002-02-06 2006-02-01 Univ Johns Hopkins Med Procedes et compositions de ciblage de reponse immunitaire systemique contre un organe ou un tissu specifique
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CA2512812A1 (fr) 2003-01-09 2004-07-29 The Trustees Of The University Of Pennsylvania Compositions, methodes et trousses renforcant l'immunogenecite d'un vecteur de vaccin bacterien
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US8906664B2 (en) * 2004-08-13 2014-12-09 The Trustees Of The University Of Pennsylvania Methods for constructing antibiotic resistance free vaccines
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WO2007061848A2 (fr) 2005-11-17 2007-05-31 The Trustees Of The University Of Pennsylvania Procedes pour la production, la culture, et la conservation de vecteurs vaccinaux de listeria
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US20060204516A1 (en) 2006-09-14
JP2004500405A (ja) 2004-01-08
US20050118184A1 (en) 2005-06-02
IL151942A0 (en) 2003-04-10
US7655238B2 (en) 2010-02-02
CA2404164A1 (fr) 2001-10-04
EP1303299B1 (fr) 2010-07-28
US7635479B2 (en) 2009-12-22
EP1303299A1 (fr) 2003-04-23
US20070003567A1 (en) 2007-01-04
EP1303299A4 (fr) 2005-01-26
WO2001072329A1 (fr) 2001-10-04
US7588930B2 (en) 2009-09-15

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