ATE92335T1 - Reinigung von keuchhustenantigenen. - Google Patents

Reinigung von keuchhustenantigenen.

Info

Publication number
ATE92335T1
ATE92335T1 AT87300387T AT87300387T ATE92335T1 AT E92335 T1 ATE92335 T1 AT E92335T1 AT 87300387 T AT87300387 T AT 87300387T AT 87300387 T AT87300387 T AT 87300387T AT E92335 T1 ATE92335 T1 AT E92335T1
Authority
AT
Austria
Prior art keywords
lpf
produced
fha
purification
fimbrial
Prior art date
Application number
AT87300387T
Other languages
English (en)
Inventor
Andrew Robinson
Lawrence Ian Irons
Original Assignee
Health Lab Service Board
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Health Lab Service Board filed Critical Health Lab Service Board
Application granted granted Critical
Publication of ATE92335T1 publication Critical patent/ATE92335T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K2039/10—Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT87300387T 1986-01-20 1987-01-16 Reinigung von keuchhustenantigenen. ATE92335T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868601279A GB8601279D0 (en) 1986-01-20 1986-01-20 Purification of pertussis antigens
EP87300387A EP0231083B1 (de) 1986-01-20 1987-01-16 Reinigung von Keuchhustenantigenen

Publications (1)

Publication Number Publication Date
ATE92335T1 true ATE92335T1 (de) 1993-08-15

Family

ID=10591636

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87300387T ATE92335T1 (de) 1986-01-20 1987-01-16 Reinigung von keuchhustenantigenen.

Country Status (11)

Country Link
US (1) US4784589A (de)
EP (1) EP0231083B1 (de)
JP (1) JP2538224B2 (de)
KR (1) KR950010323B1 (de)
CN (1) CN1028206C (de)
AT (1) ATE92335T1 (de)
AU (1) AU592727B2 (de)
CA (1) CA1280693C (de)
DE (1) DE3786806T2 (de)
DK (1) DK172936B1 (de)
GB (1) GB8601279D0 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1337859C (en) * 1987-04-24 1996-01-02 Masashi Chazono Method for culturing bordetella pertussis, a pertussis toxoid and a pertussis vaccine
GB8807860D0 (en) * 1988-04-05 1988-05-05 Connaught Lab Pertussis vaccine
CA1341123C (en) * 1988-10-27 2000-10-17 David A. Relman Filamentous hemagglutinin of b. pertussis
JP2706792B2 (ja) * 1988-11-29 1998-01-28 財団法人化学及血清療法研究所 百日咳毒素のトキソイド化法
GB8910570D0 (en) * 1989-05-08 1989-06-21 Wellcome Found Acellular vaccine
US5391715A (en) * 1989-11-06 1995-02-21 Smithkline Beecham Biologicals Method for isolating and purifying bordetella pertussis antigenic factors
DK0427462T3 (da) 1989-11-06 1996-03-11 Smithkline Beecham Biolog Fremgangsmåde
AU646019B2 (en) * 1990-02-12 1994-02-03 Smithkline Beecham Biologicals (Sa) Novel vaccine and method therefor
EP0484621A3 (en) * 1990-07-11 1992-08-26 American Cyanamid Company Efficacious vaccines against bordetella pertussis comprising a combination of individually purified pertussis antigens
US5445817A (en) * 1992-08-21 1995-08-29 The United States Of America As Represented By The Department Of Health And Human Services Pertussis toxin used as a carrier protein with non-charged saccharides in conjugate vaccines
ATE183194T1 (de) * 1994-04-28 1999-08-15 Takeda Chemical Industries Ltd Verfahren zur trennung von protektiven verbindungen aus bordetella pertussis
EP1234579A1 (de) * 1995-05-04 2002-08-28 Aventis Pasteur Limited Azelluläre Pertussis-Impfstoffe und Verfahren zu deren Herstellung
US7091311B2 (en) * 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
US8067367B2 (en) 2002-09-18 2011-11-29 Janssen Pharmaceutica, N.V. Methods of increasing platelet and hematopoietic stem cell production
US8916173B2 (en) 2013-03-08 2014-12-23 Crucell Holland B.V. Acellular pertussis vaccine
CN110358802B (zh) * 2019-08-16 2021-06-18 长春百克生物科技股份公司 一种去除百日咳组分菌毛蛋白2/3内毒素的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4247452A (en) * 1978-03-01 1981-01-27 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland Purification of pertussis haemagglutinins
JPS5750925A (en) * 1980-09-12 1982-03-25 Takeda Chem Ind Ltd Preparation of pertussis toxoid
US4474758A (en) * 1981-11-19 1984-10-02 American Cyanamid Company Haemophilus influenzae type b and pertussis outer membrane component combined vaccine
HU188847B (en) * 1983-02-22 1986-05-28 Human Oltoanyagtermeloe Es Kutato Intezet,Hu Process for producing liophylized combined vaccines
CA1213234A (en) * 1983-03-30 1986-10-28 Akihiro Ginnaga Method for the production of ha fraction containing protective antigens of bordetella pertussis and pertussis vaccine
US4551429A (en) * 1983-09-15 1985-11-05 American Home Products Corporation Stimulation of antigen production by Bordetella pertussis
JPS6098988A (ja) * 1983-11-01 1985-06-01 Chemo Sero Therapeut Res Inst Ｌｐｆ−ｈａの精製法
AU571078B2 (en) * 1984-04-14 1988-03-31 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Purification of filamentous hemagglutinin

Also Published As

Publication number Publication date
CA1280693C (en) 1991-02-26
AU6766487A (en) 1987-07-23
DK172936B1 (da) 1999-10-11
KR870006902A (ko) 1987-08-13
CN87100399A (zh) 1987-09-09
GB8601279D0 (en) 1986-02-26
DK27287D0 (da) 1987-01-19
DK27287A (da) 1987-07-21
EP0231083A2 (de) 1987-08-05
DE3786806D1 (de) 1993-09-09
EP0231083A3 (en) 1988-06-08
KR950010323B1 (ko) 1995-09-14
JPS62234031A (ja) 1987-10-14
CN1028206C (zh) 1995-04-19
JP2538224B2 (ja) 1996-09-25
EP0231083B1 (de) 1993-08-04
US4784589A (en) 1988-11-15
AU592727B2 (en) 1990-01-18
DE3786806T2 (de) 1993-12-09

Similar Documents

Publication Publication Date Title
ATE92335T1 (de) Reinigung von keuchhustenantigenen.
MX9708481A (es) Vacunas acelulares de pertussis y metodos de preparacion de las mismas.
DK496485D0 (da) Transformation af gaer-stammer af slaegten pichia
ATE180477T1 (de) Verfahren und zubereitungen zur isolierung von taxanen
DE3750751D1 (de) Gaschromatographische Methode zur Trennung von Wasserstoffisotopen.
DK0522291T3 (da) Fremgangsmåde til rensning af hepatitis A-virus (HAV), således renset virus og vaccinepræparater indeholdende dette
DE761230T1 (de) Aus Bordetella pertussis Aussenmembranprotein enthaltender Impfstoffe und Verfahren zu seiner Herstellung
SE8402861D0 (sv) Rening av biologiskt material
ATE97448T1 (de) Verfahren zur isolierung von ca 125-antigen.
AU2352595A (en) Method of separating protective components of bordetella pertussis
ZA908801B (en) Process for purifying antigenic factors from b.pertussis
DE59007659D1 (de) Matrix mit daran adhärent gebundenen zellen, sowie verfahren zur produktion von virus/virusantigen.
AT384032B (de) Verfahren zur herstellung von polydispersen nativen pseudomonas-flagella(h)-antigenen (fag)
ES474611A1 (es) Procedimiento para aislar y purificar fosfato de poliribosilribitol inmunologicamente activo
JPS5464683A (en) Preparation of unicellular protein
JPS5675095A (en) Preparation of heat-resistant acetic acid kinase
DK0408742T3 (da) Fremgangsmåde til fremstilling og rensning af hepatitis B vaccine
JPS5750892A (en) Microbial preparation of valeric acid derivative
DK222887A (da) Fremgangsmaade til fremstilling af l-aminosyrer ved fermentering af alfa-ketocarboxylsyrer
ATE109353T1 (de) Verfahren zur herstellung eines impfstoffs gegen hepatitis b.
JPS5539730A (en) Preparation of ubiquinone q10
FI98466B (fi) FSME-viruksen läntisen alatyypin eristettyjä DNA- ja RNA-molekyylejä, näitä sisältäviä vektoreita ja soluviljelmiä sekä menetelmä näiden koodittamien peptidien valmistamiseksi
TH20014A (th) วิธีการแยกส่วนประกอบป้องกันโรคไอกรนของ Bordetella pertussis

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties