ATE90083T1 - Cinnolin-karbonsaeure-amide und verfahren zu deren herstellung. - Google Patents
Cinnolin-karbonsaeure-amide und verfahren zu deren herstellung.Info
- Publication number
- ATE90083T1 ATE90083T1 AT88300823T AT88300823T ATE90083T1 AT E90083 T1 ATE90083 T1 AT E90083T1 AT 88300823 T AT88300823 T AT 88300823T AT 88300823 T AT88300823 T AT 88300823T AT E90083 T1 ATE90083 T1 AT E90083T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- unsubstituted
- substituted
- alkoxy
- halogen
- Prior art date
Links
- -1 CARBON ACID AMIDES Chemical class 0.000 title abstract 7
- 229910052799 carbon Inorganic materials 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 7
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 125000003837 (C1-C20) alkyl group Chemical group 0.000 abstract 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- 125000004485 2-pyrrolidinyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])([H])C1([H])* 0.000 abstract 1
- 125000004575 3-pyrrolidinyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000037581 Persistent Infection Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002519 immonomodulatory effect Effects 0.000 abstract 1
- 125000000842 isoxazolyl group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000005936 piperidyl group Chemical group 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000335 thiazolyl group Chemical group 0.000 abstract 1
- 125000005505 thiomorpholino group Chemical group 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/28—Cinnolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878702288A GB8702288D0 (en) | 1987-02-02 | 1987-02-02 | Cinnoline-carboxamides |
| EP88300823A EP0277791B1 (de) | 1987-02-02 | 1988-02-01 | Cinnolin-Karbonsäure-Amide und Verfahren zu deren Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE90083T1 true ATE90083T1 (de) | 1993-06-15 |
Family
ID=10611587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88300823T ATE90083T1 (de) | 1987-02-02 | 1988-02-01 | Cinnolin-karbonsaeure-amide und verfahren zu deren herstellung. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4826837A (de) |
| EP (1) | EP0277791B1 (de) |
| JP (1) | JPS63225363A (de) |
| AT (1) | ATE90083T1 (de) |
| AU (1) | AU605541B2 (de) |
| CA (1) | CA1309407C (de) |
| DE (1) | DE3881407T2 (de) |
| DK (1) | DK48488A (de) |
| ES (1) | ES2058247T3 (de) |
| FI (1) | FI91405C (de) |
| GB (1) | GB8702288D0 (de) |
| HU (1) | HU207053B (de) |
| IE (1) | IE61161B1 (de) |
| IL (1) | IL85221A (de) |
| MY (1) | MY103055A (de) |
| NZ (1) | NZ223350A (de) |
| PT (1) | PT86677B (de) |
| SU (1) | SU1563592A3 (de) |
| ZA (1) | ZA88686B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8513639D0 (en) * | 1985-05-30 | 1985-07-03 | Ici America Inc | Cinnoline compounds |
| FR2683221B1 (fr) * | 1991-11-04 | 1994-03-04 | Fabre Medicament Pierre | Nouveaux derives de cinnolinones-4, leur preparation et leur application en therapeutique. |
| JPH05310732A (ja) * | 1992-03-12 | 1993-11-22 | Mitsubishi Kasei Corp | シンノリン−３−カルボン酸誘導体 |
| US7217722B2 (en) | 2000-02-01 | 2007-05-15 | Kirin Beer Kabushiki Kaisha | Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same |
| KR20020093849A (ko) | 2000-03-21 | 2002-12-16 | 파마시아 앤드 업존 캄파니 | 항바이러스제로서의4-옥소-1,4-디히드로[1,8]나프티리딘-3-카르복스아미드 |
| NZ521523A (en) | 2000-03-21 | 2004-05-28 | Upjohn Co | 4-hydroxy-1,8-naphthyridine-3-carboxamides as antiviral agents |
| CA2399741A1 (en) * | 2000-03-21 | 2001-11-01 | Scott D. Larsen | 4-hydroxycinnoline-3-carboxyamides as antiviral agents |
| KR20020081479A (ko) * | 2000-03-21 | 2002-10-26 | 파마시아 앤드 업존 캄파니 | 항바이러스제인4-옥소-1,4-디히드로-3-신놀린카르복스아미드 |
| CN101849943A (zh) * | 2005-06-06 | 2010-10-06 | 菲布罗根公司 | 使用HIFα稳定剂的改进的贫血治疗 |
| TW200911760A (en) * | 2007-06-19 | 2009-03-16 | Astrazeneca Ab | Compounds and uses thereof |
| KR101713402B1 (ko) * | 2015-03-06 | 2017-03-07 | 엘지전자 주식회사 | 조리기기 |
| JP2025521347A (ja) * | 2022-06-23 | 2025-07-08 | ランクセス・ドイチュランド・ゲーエムベーハー | エトキシル化アルコールを含むゴム混合物 |
| EP4296075A1 (de) * | 2022-06-23 | 2023-12-27 | LANXESS Deutschland GmbH | Kautschukmischungen enthaltend ethoxylierten alkohol |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1474399A (en) * | 1974-08-19 | 1977-05-25 | Ici Ltd | Cinnolin-3-yl carboxylic acids and derivatives thereof |
| GB1472766A (en) * | 1974-11-07 | 1977-05-04 | Ici Ltd | Hydroxycinnoline derivatives processes for their preparation and their use in pharmaceutical compositions |
| US4085103A (en) * | 1974-11-07 | 1978-04-18 | Imperial Chemical Industries Limited | 6-Substituted-4-hydroxycinnolin-3-yl-carboxylic acids and esters thereof |
| GB8513639D0 (en) * | 1985-05-30 | 1985-07-03 | Ici America Inc | Cinnoline compounds |
-
1987
- 1987-02-02 GB GB878702288A patent/GB8702288D0/en active Pending
-
1988
- 1988-01-26 US US07/148,702 patent/US4826837A/en not_active Expired - Fee Related
- 1988-01-27 IL IL85221A patent/IL85221A/xx not_active IP Right Cessation
- 1988-01-28 FI FI880376A patent/FI91405C/fi not_active IP Right Cessation
- 1988-01-28 AU AU10908/88A patent/AU605541B2/en not_active Ceased
- 1988-01-29 DK DK048488A patent/DK48488A/da not_active Application Discontinuation
- 1988-01-29 NZ NZ223350A patent/NZ223350A/xx unknown
- 1988-02-01 ES ES88300823T patent/ES2058247T3/es not_active Expired - Lifetime
- 1988-02-01 AT AT88300823T patent/ATE90083T1/de not_active IP Right Cessation
- 1988-02-01 PT PT86677A patent/PT86677B/pt not_active IP Right Cessation
- 1988-02-01 EP EP88300823A patent/EP0277791B1/de not_active Expired - Lifetime
- 1988-02-01 IE IE26488A patent/IE61161B1/en not_active IP Right Cessation
- 1988-02-01 CA CA000557868A patent/CA1309407C/en not_active Expired - Lifetime
- 1988-02-01 DE DE88300823T patent/DE3881407T2/de not_active Expired - Fee Related
- 1988-02-01 SU SU884355119A patent/SU1563592A3/ru active
- 1988-02-01 ZA ZA88686A patent/ZA88686B/xx unknown
- 1988-02-01 HU HU88435A patent/HU207053B/hu unknown
- 1988-02-02 JP JP63022671A patent/JPS63225363A/ja active Pending
- 1988-02-02 MY MYPI88000096A patent/MY103055A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU605541B2 (en) | 1991-01-17 |
| DK48488A (da) | 1988-08-03 |
| AU1090888A (en) | 1988-08-04 |
| DE3881407T2 (de) | 1993-09-30 |
| PT86677A (pt) | 1988-03-01 |
| CA1309407C (en) | 1992-10-27 |
| GB8702288D0 (en) | 1987-03-11 |
| DE3881407D1 (de) | 1993-07-08 |
| IE880264L (en) | 1988-08-02 |
| IE61161B1 (en) | 1994-10-05 |
| PT86677B (pt) | 1992-04-30 |
| NZ223350A (en) | 1990-08-28 |
| ES2058247T3 (es) | 1994-11-01 |
| HUT56551A (en) | 1991-09-30 |
| ZA88686B (en) | 1989-10-25 |
| HU207053B (en) | 1993-03-01 |
| FI91405C (fi) | 1994-06-27 |
| MY103055A (en) | 1993-04-30 |
| EP0277791B1 (de) | 1993-06-02 |
| US4826837A (en) | 1989-05-02 |
| IL85221A0 (en) | 1988-07-31 |
| JPS63225363A (ja) | 1988-09-20 |
| FI880376A0 (fi) | 1988-01-28 |
| EP0277791A2 (de) | 1988-08-10 |
| FI91405B (fi) | 1994-03-15 |
| FI880376A7 (fi) | 1988-08-03 |
| SU1563592A3 (ru) | 1990-05-07 |
| IL85221A (en) | 1992-09-06 |
| DK48488D0 (da) | 1988-01-29 |
| EP0277791A3 (en) | 1990-04-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |