ATE81337T1 - Von benzocyclischen oder benzoheterocyclischen saeuren abgeleitete sulfonamide, ihre herstellung und ihre anwendung in der heilkunde. - Google Patents

Von benzocyclischen oder benzoheterocyclischen saeuren abgeleitete sulfonamide, ihre herstellung und ihre anwendung in der heilkunde.

Info

Publication number
ATE81337T1
ATE81337T1 AT90400923T AT90400923T ATE81337T1 AT E81337 T1 ATE81337 T1 AT E81337T1 AT 90400923 T AT90400923 T AT 90400923T AT 90400923 T AT90400923 T AT 90400923T AT E81337 T1 ATE81337 T1 AT E81337T1
Authority
AT
Austria
Prior art keywords
branched
benzocyclic
radical
lower alkyl
benzoheterocyclic
Prior art date
Application number
AT90400923T
Other languages
German (de)
English (en)
Inventor
Dennis Bigg
Alain Duflos
Jean-Pierre Rieu
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Application granted granted Critical
Publication of ATE81337T1 publication Critical patent/ATE81337T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyrane Compounds (AREA)
AT90400923T 1989-04-05 1990-04-04 Von benzocyclischen oder benzoheterocyclischen saeuren abgeleitete sulfonamide, ihre herstellung und ihre anwendung in der heilkunde. ATE81337T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR898904470A FR2645537B1 (fr) 1989-04-05 1989-04-05 Nouveaux sulfonamides derives d'acides benzocycliques ou benzoheterocycliques, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ATE81337T1 true ATE81337T1 (de) 1992-10-15

Family

ID=9380405

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90400923T ATE81337T1 (de) 1989-04-05 1990-04-04 Von benzocyclischen oder benzoheterocyclischen saeuren abgeleitete sulfonamide, ihre herstellung und ihre anwendung in der heilkunde.

Country Status (14)

Country Link
US (1) US5385931A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0391799B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH03505335A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE81337T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU624951B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2030566A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69000364T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0391799T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2053133T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2645537B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3006746T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (2) HU210746B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1990012007A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA902633B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0589037B1 (en) * 1991-03-01 1996-05-29 Zeria Pharmaceutical Co., Ltd. Indian derivative and thromboxane antagonist containing the same
FI963477L (fi) 1995-01-06 1996-11-04 Toray Industries Benseenin kanssa renkaaksi suljettu heterosyklinen johdannainen
US5686471A (en) * 1996-02-01 1997-11-11 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5618835A (en) * 1996-02-01 1997-04-08 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684031A (en) * 1996-02-01 1997-11-04 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
AU711159B2 (en) 1996-02-22 1999-10-07 Tularik Inc. Pentafluorobenzenesulfonamides and analogs
EP0909184B1 (en) * 1996-07-03 2003-09-17 PHARMACIA & UPJOHN COMPANY Targeted drug delivery using sulfonamide derivatives
ATE249214T1 (de) 1996-07-19 2003-09-15 Tularik Inc Pentafluorobenzensulfonamide und analoge
WO1999067258A1 (en) 1998-06-25 1999-12-29 Tularik Inc. Arylsulfonanilide phosphates
US6153585A (en) * 1998-07-20 2000-11-28 Tularik Inc. Arylsulfonanilide derivatives
HUP0103884A3 (en) 1998-09-23 2002-11-28 Tularik Inc South San Francisc Arylsulfonanilide urea-derivatives, pharmaceutical compositions containing them and their use
KR100685059B1 (ko) 1999-07-29 2007-02-22 암젠 인크 펜타플루오로벤젠술폰아미드를 사용하는 복합 치료법
WO2002039958A2 (en) 2000-11-03 2002-05-23 Tularik Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
US20050250854A1 (en) * 2000-11-03 2005-11-10 Amgen Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
ATE400564T1 (de) * 2002-07-30 2008-07-15 Merck & Co Inc Ppar alpha selektive verbindungen zur behandlung von dyslipidämie und anderen lipidstörungen
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
US7514461B2 (en) 2003-09-19 2009-04-07 Edison Pharmaceuticals, Inc. Chroman derivatives
US20060025445A1 (en) * 2004-08-02 2006-02-02 Xiang Jason S 11-Beta HSD1 inhibitors
EP2484725B1 (en) * 2009-09-30 2017-07-19 Adeka Corporation Polyester resin composition, polyester fiber, polyester resin molded article, and process for production of nucleating agent for polyester resin
JP5563282B2 (ja) * 2009-12-04 2014-07-30 株式会社Ａｄｅｋａ ポリエステル樹脂用結晶核剤の製造方法

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Publication number Priority date Publication date Assignee Title
GB1007772A (en) * 1960-12-22 1965-10-22 Rieter Ag Maschf Improvements in or relating to an automatic carding plant
FR1461111A (fr) * 1965-12-21 1966-01-07 Ethyl Corp Procédé de fabrication d'éthers thiophényliques
CH612221A5 (en) * 1976-08-12 1979-07-13 Fiber Controls Corp Apparatus for forming a fibre web
DE2939968C2 (de) * 1979-10-02 1982-09-02 Temafa, Textilmaschinenfabrik Meissner, Morgner & Co Gmbh, 5070 Bergisch Gladbach Füllschacht für eine Krempelspeiseeinrichtung
GB2118552A (en) * 1982-04-15 1983-11-02 Pfizer Ltd Thromboxane synthetase inhibitors
JPS60181067A (ja) * 1984-02-27 1985-09-14 Takeda Chem Ind Ltd ベンゾイル尿素誘導体，その製造法及び殺虫剤
DE3569129D1 (en) * 1984-09-18 1989-05-03 Rieter Ag Maschf Feeding hopper structure for fibre material
DE3623944A1 (de) * 1986-07-16 1988-02-11 Thomae Gmbh Dr K Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
IL83230A (en) * 1986-08-06 1992-06-21 Tanabe Seiyaku Co Phenoxyacetic acid derivatives,their preparation and pharmaceutical compositions containing them
DE3734140C2 (de) * 1987-10-09 1999-01-28 Truetzschler Gmbh & Co Kg Vorrichtung zur Vergleichmäßigung des einer Karde, Krempel, Reiniger o. dgl. zuzuführenden Faserflockenvlieses
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Also Published As

Publication number Publication date
JPH03505335A (ja) 1991-11-21
EP0391799B1 (fr) 1992-10-07
GR3006746T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-06-30
CA2030566A1 (fr) 1990-10-06
HU210746B (en) 1995-07-28
ES2053133T3 (es) 1994-07-16
WO1990012007A1 (fr) 1990-10-18
AU624951B2 (en) 1992-06-25
HU903397D0 (en) 1991-08-28
DE69000364T2 (de) 1993-05-06
HUT57758A (en) 1991-12-30
FR2645537A1 (fr) 1990-10-12
DE69000364D1 (de) 1992-11-12
DK0391799T3 (da) 1993-02-22
HU211872A9 (en) 1995-12-28
EP0391799A1 (fr) 1990-10-10
FR2645537B1 (fr) 1994-03-04
ZA902633B (en) 1991-01-30
US5385931A (en) 1995-01-31
AU5541890A (en) 1990-11-05

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee