ATE75607T1 - Mehrschichtige granula. - Google Patents
Mehrschichtige granula.Info
- Publication number
- ATE75607T1 ATE75607T1 AT89101806T AT89101806T ATE75607T1 AT E75607 T1 ATE75607 T1 AT E75607T1 AT 89101806 T AT89101806 T AT 89101806T AT 89101806 T AT89101806 T AT 89101806T AT E75607 T1 ATE75607 T1 AT E75607T1
- Authority
- AT
- Austria
- Prior art keywords
- layered
- granula
- releasing layer
- layer
- slow
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Glass Compositions (AREA)
- Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP63023215A JP2643222B2 (ja) | 1988-02-03 | 1988-02-03 | 多重層顆粒 |
EP89101806A EP0327086B1 (de) | 1988-02-03 | 1989-02-02 | Mehrschichtige Granula |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE75607T1 true ATE75607T1 (de) | 1992-05-15 |
Family
ID=12104439
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT89101806T ATE75607T1 (de) | 1988-02-03 | 1989-02-02 | Mehrschichtige granula. |
Country Status (11)
Country | Link |
---|---|
US (1) | US4994279A (de) |
EP (1) | EP0327086B1 (de) |
JP (1) | JP2643222B2 (de) |
KR (1) | KR910004582B1 (de) |
CN (1) | CN1031036C (de) |
AT (1) | ATE75607T1 (de) |
CA (1) | CA1337899C (de) |
DE (1) | DE68901384D1 (de) |
ES (1) | ES2031290T3 (de) |
PH (1) | PH26515A (de) |
PT (1) | PT89600B (de) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0386440T3 (da) * | 1989-02-11 | 1992-09-14 | Bayer Ag | Lægemidler med kontrolleret afgivelse af virksomt stof |
AU651084B2 (en) * | 1990-01-30 | 1994-07-14 | Akzo N.V. | Article for the controlled delivery of an active substance, comprising a hollow space fully enclosed by a wall and filled in full or in part with one or more active substances |
US5126147A (en) * | 1990-02-08 | 1992-06-30 | Biosearch, Inc. | Sustained release dosage form |
KR100221695B1 (ko) * | 1991-08-12 | 1999-09-15 | 그린 마틴, 브라이언 쥐 테슬리 | 약학적 구상 제형 |
US5225202A (en) * | 1991-09-30 | 1993-07-06 | E. R. Squibb & Sons, Inc. | Enteric coated pharmaceutical compositions |
US5407686A (en) * | 1991-11-27 | 1995-04-18 | Sidmak Laboratories, Inc. | Sustained release composition for oral administration of active ingredient |
US5478577A (en) † | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
WO1996010996A1 (en) * | 1993-07-21 | 1996-04-18 | The University Of Kentucky Research Foundation | A multicompartment hard capsule with control release properties |
US5430021A (en) * | 1994-03-18 | 1995-07-04 | Pharmavene, Inc. | Hydrophobic drug delivery systems |
US5395626A (en) * | 1994-03-23 | 1995-03-07 | Ortho Pharmaceutical Corporation | Multilayered controlled release pharmaceutical dosage form |
DE4443175A1 (de) * | 1994-12-05 | 1996-06-13 | Jenapharm Gmbh | Neue pulsatile Arzneiform |
US5744164A (en) * | 1994-12-16 | 1998-04-28 | Nestec S.A. | Sustained release microparticulate caffeine formulation |
ES2129356B1 (es) * | 1997-03-26 | 2000-01-16 | Pierre Fabre Iberica S A | Forma farmaceutica de liberacion prolongada y procedimiento para su o btencion. |
US6183482B1 (en) * | 1997-10-01 | 2001-02-06 | Scimed Life Systems, Inc. | Medical retrieval basket with legs shaped to enhance capture and reduce trauma |
TW477702B (en) | 1997-10-23 | 2002-03-01 | Dev Center Biotechnology | Controlled release tacrine dosage form |
EP0928610A1 (de) * | 1998-01-08 | 1999-07-14 | Development Center For Biotechnology | Tacrine enthaltende Dosierungsform zur kontrollierten Freigabe |
US7122207B2 (en) * | 1998-05-22 | 2006-10-17 | Bristol-Myers Squibb Company | High drug load acid labile pharmaceutical composition |
UA69413C2 (uk) | 1998-05-22 | 2004-09-15 | Брістол-Майерс Сквібб Компані | Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції |
UA73092C2 (uk) | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Таблетка з ентеросолюбільним покриттям і спосіб її приготування |
US6555139B2 (en) | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
AU7581800A (en) * | 1999-09-14 | 2001-04-17 | Smithkline Beecham Corporation | Process for making aqueous coated beadlets |
GB0007419D0 (en) | 2000-03-27 | 2000-05-17 | Smithkline Beecham Gmbh | Composition |
US7670612B2 (en) | 2002-04-10 | 2010-03-02 | Innercap Technologies, Inc. | Multi-phase, multi-compartment capsular delivery apparatus and methods for using same |
EP2422775A3 (de) * | 2002-09-20 | 2012-04-18 | Alpharma, Inc. | Sequestriermitteluntereinheit und zugehörige Zusammensetzungen und Verfahren |
US9107804B2 (en) | 2002-12-10 | 2015-08-18 | Nortec Development Associates, Inc. | Method of preparing biologically active formulations |
WO2005123042A1 (en) * | 2004-06-10 | 2005-12-29 | Glatt Air Techniques, Inc. | Controlled release pharmaceutical formulation |
US20090208579A1 (en) * | 2004-12-27 | 2009-08-20 | Eisai R & D Management Co., Ltd. | Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same |
US8481565B2 (en) * | 2004-12-27 | 2013-07-09 | Eisai R&D Management Co., Ltd. | Method for stabilizing anti-dementia drug |
US20060280789A1 (en) * | 2004-12-27 | 2006-12-14 | Eisai Research Institute | Sustained release formulations |
SI2484346T1 (sl) | 2006-06-19 | 2017-05-31 | Alpharma Pharmaceuticals Llc | Farmacevtski sestavki |
US20080233156A1 (en) * | 2006-10-11 | 2008-09-25 | Alpharma, Inc. | Pharmaceutical compositions |
US8110226B2 (en) * | 2007-07-20 | 2012-02-07 | Mylan Pharmaceuticals Inc. | Drug formulations having inert sealed cores |
US8486452B2 (en) * | 2007-07-20 | 2013-07-16 | Mylan Pharmaceuticals Inc. | Stabilized tolterodine tartrate formulations |
US9763989B2 (en) | 2007-08-03 | 2017-09-19 | Shaklee Corporation | Nutritional supplement system |
WO2009020595A2 (en) * | 2007-08-03 | 2009-02-12 | Shaklee Corporation | Nutritional supplement system |
US8323695B2 (en) * | 2007-08-13 | 2012-12-04 | Mcneil-Ppc, Inc. | Method for stabilizing phenylephrine |
IL199781A0 (en) | 2009-07-09 | 2010-05-17 | Yohai Zorea | Heat resistant probiotic compositions and healthy food comprising them |
AU2008346870A1 (en) * | 2007-12-17 | 2009-07-16 | Alpharma Pharmaceuticals, Llc | Pharmaceutical composition |
AU2008338442A1 (en) * | 2007-12-17 | 2009-06-25 | Alpharma Pharmaceuticals, Llc | Pharmaceutical composition |
US20100151014A1 (en) * | 2008-12-16 | 2010-06-17 | Alpharma Pharmaceuticals, Llc | Pharmaceutical composition |
US8623418B2 (en) * | 2007-12-17 | 2014-01-07 | Alpharma Pharmaceuticals Llc | Pharmaceutical composition |
CA2820178A1 (en) | 2010-12-06 | 2012-06-14 | Degama Berrier Ltd. | Composition and method for improving stability and extending shelf life of probiotic bacteria and food products thereof |
US10543175B1 (en) | 2013-05-17 | 2020-01-28 | Degama Berrier Ltd. | Film composition and methods for producing the same |
CA2936746C (en) | 2014-10-31 | 2017-06-27 | Purdue Pharma | Methods and compositions particularly for treatment of attention deficit disorder |
CN106035323B (zh) * | 2016-05-25 | 2018-12-11 | 广西南宁农事帮农业科技服务有限公司 | 一种缓释农药颗粒剂及其制备方法 |
CN107188722A (zh) * | 2017-07-12 | 2017-09-22 | 山东棉花研究中心 | 一种组合式短季棉专用配方肥 |
US10722473B2 (en) | 2018-11-19 | 2020-07-28 | Purdue Pharma L.P. | Methods and compositions particularly for treatment of attention deficit disorder |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2921883A (en) * | 1957-05-03 | 1960-01-19 | Smith Kline French Lab | Novel coating material for medicaments |
NL235736A (de) * | 1958-02-03 | |||
NL122039C (de) * | 1960-10-20 | |||
UST861008I4 (en) * | 1968-05-16 | 1969-04-01 | Defensive publication | |
US3577512A (en) * | 1968-10-11 | 1971-05-04 | Nat Patent Dev Corp | Sustained release tablets |
US3879511A (en) * | 1972-07-03 | 1975-04-22 | Warner Lambert Co | Tasteless methenamine mandelate in a stabilized vegetable oil suspension |
JPS52139715A (en) * | 1976-05-14 | 1977-11-21 | Nippon Kayaku Co Ltd | Coated granules of alkali polyacrylate |
FR2377196A1 (fr) * | 1977-01-13 | 1978-08-11 | Lipha | Composition medicamenteuse a usage oral |
US4122157A (en) * | 1977-03-04 | 1978-10-24 | Richardson-Merrell Inc. | Nitrofurantoin sustained release tablet |
GB1561204A (en) * | 1977-06-01 | 1980-02-13 | Ici Ltd | Sustained release pharmaceutical composition |
GB1594102A (en) * | 1977-09-26 | 1981-07-30 | Sankyo Co | Ingestible coating compositions |
IE48715B1 (en) * | 1978-12-22 | 1985-05-01 | Elan Corp Plc | New galencial forms for administration of medicaments by oral route,with programmed release and processes for preparing same |
JPS55153715A (en) * | 1979-05-18 | 1980-11-29 | Nikken Kagaku Kk | Prolonged granule of theophylline |
CA1146866A (en) * | 1979-07-05 | 1983-05-24 | Yamanouchi Pharmaceutical Co. Ltd. | Process for the production of sustained release pharmaceutical composition of solid medical material |
US4309406A (en) * | 1979-07-10 | 1982-01-05 | American Home Products Corporation | Sustained release pharmaceutical compositions |
US4309405A (en) * | 1979-08-09 | 1982-01-05 | American Home Products Corporation | Sustained release pharmaceutical compositions |
JPS5770816A (en) * | 1980-10-17 | 1982-05-01 | Ono Pharmaceut Co Ltd | Multilayered film preparation of prostagladin of prolonged action |
JPS5839618A (ja) * | 1981-09-04 | 1983-03-08 | Chugai Pharmaceut Co Ltd | 持続性積層錠剤 |
JPS58134019A (ja) * | 1982-02-05 | 1983-08-10 | Ono Pharmaceut Co Ltd | プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法 |
US4634587A (en) * | 1982-07-09 | 1987-01-06 | Key Pharmaceuticals, Inc. | Sustained release quinidine dosage form |
JPS59155309A (ja) * | 1983-02-22 | 1984-09-04 | Teijin Ltd | 活性型ビタミンd↓3類組成物 |
DE3403329A1 (de) * | 1984-02-01 | 1985-08-01 | Horst Dr. 4019 Monheim Zerbe | Pharmazeutisches produkt in form von pellets mit kontinuierlicher, verzoegerter wirkstoffabgabe |
US4572883A (en) * | 1984-06-11 | 1986-02-25 | Xerox Corporation | Electrophotographic imaging member with charge injection layer |
US4600645A (en) * | 1985-01-31 | 1986-07-15 | Warner-Lambert Company | Process for treating dosage forms |
US4568536A (en) * | 1985-02-08 | 1986-02-04 | Ethicon, Inc. | Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition |
NL8500724A (nl) * | 1985-03-13 | 1986-10-01 | Univ Groningen | Inrichtingen voor geregelde afgifte van werkzame stoffen, alsmede werkwijze ter vervaardiging daarvan. |
JPS6261916A (ja) * | 1985-09-12 | 1987-03-18 | Fujisawa Pharmaceut Co Ltd | 持続性製剤 |
JPS62103012A (ja) * | 1985-10-23 | 1987-05-13 | Eisai Co Ltd | 多重顆粒 |
-
1988
- 1988-02-03 JP JP63023215A patent/JP2643222B2/ja not_active Expired - Fee Related
-
1989
- 1989-01-26 US US07/302,646 patent/US4994279A/en not_active Expired - Lifetime
- 1989-01-31 CA CA000589625A patent/CA1337899C/en not_active Expired - Fee Related
- 1989-02-01 KR KR1019890001165A patent/KR910004582B1/ko not_active IP Right Cessation
- 1989-02-02 ES ES198989101806T patent/ES2031290T3/es not_active Expired - Lifetime
- 1989-02-02 PT PT89600A patent/PT89600B/pt not_active IP Right Cessation
- 1989-02-02 DE DE8989101806T patent/DE68901384D1/de not_active Expired - Fee Related
- 1989-02-02 EP EP89101806A patent/EP0327086B1/de not_active Expired - Lifetime
- 1989-02-02 AT AT89101806T patent/ATE75607T1/de not_active IP Right Cessation
- 1989-02-02 CN CN89100615A patent/CN1031036C/zh not_active Expired - Fee Related
- 1989-02-03 PH PH38153A patent/PH26515A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN1037082A (zh) | 1989-11-15 |
JPH01197433A (ja) | 1989-08-09 |
EP0327086A2 (de) | 1989-08-09 |
PH26515A (en) | 1992-08-07 |
PT89600A (pt) | 1989-10-04 |
PT89600B (pt) | 1994-01-31 |
KR910004582B1 (ko) | 1991-07-06 |
EP0327086A3 (en) | 1989-09-06 |
CN1031036C (zh) | 1996-02-21 |
US4994279A (en) | 1991-02-19 |
KR890012636A (ko) | 1989-09-18 |
CA1337899C (en) | 1996-01-09 |
ES2031290T3 (es) | 1992-12-01 |
EP0327086B1 (de) | 1992-05-06 |
JP2643222B2 (ja) | 1997-08-20 |
DE68901384D1 (de) | 1992-06-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |