ATE72052T1 - Bestimmung von glycohaemoglobin (glycosyliertem haemoglobin) in blut. - Google Patents

Bestimmung von glycohaemoglobin (glycosyliertem haemoglobin) in blut.

Info

Publication number
ATE72052T1
ATE72052T1 AT86302372T AT86302372T ATE72052T1 AT E72052 T1 ATE72052 T1 AT E72052T1 AT 86302372 T AT86302372 T AT 86302372T AT 86302372 T AT86302372 T AT 86302372T AT E72052 T1 ATE72052 T1 AT E72052T1
Authority
AT
Austria
Prior art keywords
determination
hba1c
blood
glycohaemoglobin
glycosylated haemoglobin
Prior art date
Application number
AT86302372T
Other languages
English (en)
Inventor
Jesper Zeuthen
Annette Prentoe
Viggo Kruse
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE72052T1 publication Critical patent/ATE72052T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT86302372T 1985-03-29 1986-03-27 Bestimmung von glycohaemoglobin (glycosyliertem haemoglobin) in blut. ATE72052T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK145385A DK145385D0 (da) 1985-03-29 1985-03-29 Monoklonalt antistof til immunkemisk analyse
EP86302372A EP0201187B1 (de) 1985-03-29 1986-03-27 Bestimmung von Glycohämoglobin (glycosyliertem Hämoglobin) in Blut

Publications (1)

Publication Number Publication Date
ATE72052T1 true ATE72052T1 (de) 1992-02-15

Family

ID=8104987

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86302372T ATE72052T1 (de) 1985-03-29 1986-03-27 Bestimmung von glycohaemoglobin (glycosyliertem haemoglobin) in blut.

Country Status (10)

Country Link
EP (1) EP0201187B1 (de)
JP (1) JPH0720437B2 (de)
AT (1) ATE72052T1 (de)
AU (1) AU584688B2 (de)
DE (1) DE3683532D1 (de)
DK (2) DK145385D0 (de)
ES (1) ES8800351A1 (de)
FI (1) FI89379B (de)
GR (1) GR860833B (de)
PT (1) PT82296B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4727036A (en) * 1985-08-08 1988-02-23 Molecular Diagnostics, Inc. Antibodies for use in determining hemoglobin A1c
CA1339952C (en) * 1984-10-29 1998-07-14 William J. Knowles Immunoassays for denatured protein analytes, particularly hb alc, and monoclonal antibodies thereto
US4876188A (en) * 1986-11-18 1989-10-24 Scripps Clinic And Research Foundation Novel immunochemical method for assaying stable glycosylated hemoglobin
JPS63273472A (ja) * 1987-04-30 1988-11-10 Asahi Breweries Ltd 新規抗体とそれを用いたヒトヘモグロビンの検出
US4970171A (en) * 1987-11-09 1990-11-13 Miles Inc. Denaturant reagents for convenient determination of hemoglobin derivatives in blood
DE3806198A1 (de) * 1988-02-04 1989-08-17 Boehringer Mannheim Gmbh Immunogen und seine verwendung zur gewinnung von antikoerpern gegen hba(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)c(pfeil abwaerts)
ATE143673T1 (de) * 1989-08-23 1996-10-15 Univ Northwestern Testverfahren von glykosylierten proteinen unter verwendung eines antikörpers gerichtet gegen reduzierte glykosylierte n-terminal-aminosäuren
US5484735A (en) * 1989-08-23 1996-01-16 Northwestern University Immunoassay of glycosylated proteins employing antibody directed to reductively glycosylated N-terminal amino acids
US5183739A (en) * 1990-02-27 1993-02-02 Exocell, Inc. Monoclonal antibodies specific for non-a1c glycated hemoglobin and immunoassay methods
DE4206932A1 (de) * 1992-03-05 1993-09-09 Boehringer Mannheim Gmbh Immunologische methode zur bestimmung eines haemoglobinderivates
JP2596322B2 (ja) * 1992-06-10 1997-04-02 富士レビオ株式会社 総ヘモグロビンに対する糖化ヘモグロビンの割合の測定方法
US5470759A (en) * 1992-06-10 1995-11-28 Fujirebio, Inc. Anti-glycated hemoglobin monoclonal antibody and method for measuring glycated hemoglobin
JP2596321B2 (ja) * 1992-06-16 1997-04-02 富士レビオ株式会社 糖化ヘモグロビンの測定方法
WO1994000592A1 (en) * 1992-06-26 1994-01-06 Exocell, Inc. Monoclonal antibodies against glycated low density lipoprotein
AU661207B2 (en) * 1992-11-17 1995-07-13 Boehringer Mannheim Gmbh Simultaneous determination of HbA1c and haemoglobin variants with a glycation analogus to HbA1c
JP3269765B2 (ja) 1995-12-14 2002-04-02 富士写真フイルム株式会社 ヘモグロビン誘導体の免疫学的測定方法及びその方法に用いる処理試薬
JP3801133B2 (ja) * 2000-07-14 2006-07-26 松下電器産業株式会社 ペプチドフルクトース及びそのタンパク質結合体
WO2005023291A2 (en) * 2003-09-11 2005-03-17 Novo Nordisk A/S Use of glp1-agonists in the treatment of patients with type i diabetes
US7670792B2 (en) 2004-07-14 2010-03-02 The Regents Of The University Of California Biomarkers for early detection of ovarian cancer
EP2199801B1 (de) 2004-07-14 2013-05-29 The Regents of The University of California Biomarker zur Früherkennung von Eierstockkrebs
US9488655B2 (en) 2004-07-14 2016-11-08 The Regents Of The University Of California Biomarkers for detection of early- and late-stage endometrial cancer
WO2012047930A2 (en) 2010-10-04 2012-04-12 The Regents Of The University Of California Compositions and methods for treatment of gynecologic cancers
WO2013033260A1 (en) 2011-08-29 2013-03-07 The Regents Of The University Of California Use of hdl-related molecules to treat and prevent proinflammatory conditions
JP6822957B2 (ja) 2015-07-30 2021-01-27 京セラ株式会社 測定方法、および測定装置
KR20210117267A (ko) * 2019-01-17 2021-09-28 에프. 호프만-라 로슈 아게 원형 단백질 수준의 LC-MS 기반 HbA1c 측정을 위한 자동 샘플 워크플로우
MX2020005703A (es) * 2020-07-13 2022-01-14 Centro De Investig Y Asistencia En Tecnologia Y Diseno Del Estado De Jalisco A C Secuencias de dominios vnar de potamotrygon schroederi y composiciones para el reconocimiento de hemoglobina glicada humana.
CN118772272B (zh) * 2024-09-12 2024-11-08 南京立顶医疗科技有限公司 一种靶向HbA1c的重组IgM型抗体及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4247533A (en) * 1978-05-01 1981-01-27 The Rockefeller University Hemoglobin A1c radioimmunoassay
GB1580318A (en) 1978-05-06 1980-12-03 Univ Rockefeller Antibodies active against human hemoglobin a1c
US4478744A (en) 1982-01-25 1984-10-23 Sherwood Medical Company Method of obtaining antibodies
US4629692A (en) * 1982-12-06 1986-12-16 Miles Laboratories, Inc. Immunoassay for nonenzymatically glucosylated proteins and protein fragments an index of glycemia
AU529210B3 (en) * 1983-02-02 1983-04-14 Australian Monoclonal Development Pty. Ltd. Monoclonal antibody in occult blood diagnosis
JPS59202064A (ja) * 1983-04-30 1984-11-15 Fujirebio Inc 抗原決定基具有物質を測定する方法
CA1339952C (en) * 1984-10-29 1998-07-14 William J. Knowles Immunoassays for denatured protein analytes, particularly hb alc, and monoclonal antibodies thereto

Also Published As

Publication number Publication date
PT82296A (en) 1986-04-01
FI89379B (fi) 1993-06-15
EP0201187A1 (de) 1986-11-12
DK145385D0 (da) 1985-04-01
AU5532186A (en) 1986-10-02
FI861358L (fi) 1986-09-30
DK129986A (da) 1986-09-30
JPS61280571A (ja) 1986-12-11
ES553472A0 (es) 1987-10-16
FI861358A0 (fi) 1986-03-27
DK129986D0 (da) 1986-03-21
PT82296B (pt) 1988-07-29
DE3683532D1 (de) 1992-03-05
DK159826B (da) 1990-12-10
JPH0720437B2 (ja) 1995-03-08
EP0201187B1 (de) 1992-01-22
GR860833B (en) 1986-07-29
ES8800351A1 (es) 1987-10-16
DK159826C (da) 1991-04-29
AU584688B2 (en) 1989-06-01

Similar Documents

Publication Publication Date Title
DE3683532D1 (de) Bestimmung von glycohaemoglobin (glycosyliertem haemoglobin) in blut.
ATE93323T1 (de) Latex-agglutinations-immuntest in gegenwart von haemoglobin.
DK96689A (da) Fremgangsmaade til immunbestemmelse og diagnostisk middel til anvendelse ved fremgangsmaaden
DE59310046D1 (de) Immunologische Methode zur Bestimmung von HbAIc
DK622788D0 (da) Analysemetode og testsystem til bestemmelse af den relative maengde af et bestemt haemoglobinderivat i en blodproeve
DE3587687D1 (de) Monoklonale Antikörper für HbA1c.
SE7910340L (sv) Bestemning av glykosbundet hemoglobin i blod
FI823454L (fi) Foerfarande och reagens foer bestaemning av glykosilerat hemoglobin
NO934139D0 (no) Samtidig bestemmelse av HbAlc og hemoglobinvarianter med en HbAlc-analog glykosilering
ES555425A0 (es) Un metodo de medida de la concentracion de un ligando libre en un fluido biologico
FI841145A7 (fi) Menetelmä hemoglobiinipitoisuuden kvantitatiiviseksi määrittämiseksi biologisessa näytteessä.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee