|
US5212071A
(en)
*
|
1988-04-01 |
1993-05-18 |
The Johns Hopkins University |
Nucleic acids encoding a human C3b/C4b receptor (CR1)
|
|
US5981481A
(en)
*
|
1974-12-06 |
1999-11-09 |
The Johns Hopkins University |
Human C3b/C4b receptor (CR1)
|
|
US5985587A
(en)
*
|
1984-08-17 |
1999-11-16 |
The Scripps Research Institute |
Polypeptide-induced monoclonal receptors to protein ligands
|
|
US4857637A
(en)
*
|
1986-05-07 |
1989-08-15 |
Genentech, Inc. |
Methods and compositions for immunologically modulating growth hormone receptor activity
|
|
EP0267272A4
(de)
*
|
1986-05-09 |
1990-03-12 |
Biotechnology Res Associates J |
Atriales natriuretisches peptid rezeptor protein und dessen dns-kodierung.
|
|
WO1988001304A1
(en)
|
1986-08-21 |
1988-02-25 |
The Trustees Of Columbia University In The City Of |
Dna encoding the t cell surface protein t4 and use of fragments of t4 in the treatment of aids
|
|
US5126433A
(en)
*
|
1986-08-21 |
1992-06-30 |
The Trustees Of Columbia University In The City Of New York |
Soluble forms of the t cell surface protein cd4
|
|
US6673896B1
(en)
*
|
1986-08-21 |
2004-01-06 |
The Trustees Of Columbia University In The City Of New York |
Derivatives of soluble T-4
|
|
US5958678A
(en)
*
|
1986-08-21 |
1999-09-28 |
The Trustees Of Columbia University In The City Of New York |
DNA encoding the T cell surface protein T4 and use of fragments of T4 in the treatment of AIDS
|
|
AT391998B
(de)
*
|
1987-02-02 |
1990-12-27 |
Falko Dr Skrabal |
Vorrichtung zur bestimmung der konzentration zumindest einer medizinischen substanz in lebenden organismen
|
|
US5057417A
(en)
*
|
1987-06-12 |
1991-10-15 |
Genentech, Inc. |
Compositions and methods for the synthesis of growth hormone receptor and growth hormone binding protein
|
|
US5688763A
(en)
*
|
1987-06-12 |
1997-11-18 |
Hammonds, Jr.; R. Glenn |
Compositions and methods for the synthesis of growth hormone receptor and growth hormone binding protein
|
|
US5637677A
(en)
*
|
1987-07-16 |
1997-06-10 |
The Trustees Of The University Of Pennsylvania |
Biologically active compounds and methods of constructing and using the same
|
|
IL83687A
(en)
*
|
1987-08-30 |
1995-03-30 |
Yeda Res & Dev |
Pharmaceutical compositions comprising molecular decays and their use in the manufacture of said compositions
|
|
US5336603A
(en)
*
|
1987-10-02 |
1994-08-09 |
Genentech, Inc. |
CD4 adheson variants
|
|
US6710169B2
(en)
*
|
1987-10-02 |
2004-03-23 |
Genentech, Inc. |
Adheson variants
|
|
US4962155A
(en)
*
|
1987-12-07 |
1990-10-09 |
City Of Hope |
Methods and compositions for activating the human insulin receptor kinase
|
|
US5395929A
(en)
*
|
1987-12-15 |
1995-03-07 |
Dana Farber Cancer Institute |
Isolated nucleic acid encoding the alpha subunit of the human leukocyte adhesion receptor
|
|
US6018026A
(en)
*
|
1988-01-22 |
2000-01-25 |
Zymogenetics, Inc. |
Biologically active dimerized and multimerized polypeptide fusions
|
|
US5567584A
(en)
*
|
1988-01-22 |
1996-10-22 |
Zymogenetics, Inc. |
Methods of using biologically active dimerized polypeptide fusions to detect PDGF
|
|
US5750375A
(en)
*
|
1988-01-22 |
1998-05-12 |
Zymogenetics, Inc. |
Methods of producing secreted receptor analogs and biologically active dimerized polypeptide fusions
|
|
US6180368B1
(en)
*
|
1988-03-23 |
2001-01-30 |
University Of Melbourne |
Ryegrass pollen allergen
|
|
US5256642A
(en)
*
|
1988-04-01 |
1993-10-26 |
The Johns Hopkins University |
Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
|
|
ATE140233T1
(de)
*
|
1988-05-13 |
1996-07-15 |
University Patents Inc |
Von gemeinsamen sequenzen von antigenen und antiidiotypischen antikörpern oder von antikörpern mit spezifizität für die zellulären rezeptoren der antigene abgeleitete immunogene und biologisch aktive peptide
|
|
AU630882B2
(en)
*
|
1988-06-30 |
1992-11-12 |
City Of Hope |
Insulinomimetic and insulin receptor binding site peptides
|
|
US5227466A
(en)
*
|
1988-06-30 |
1993-07-13 |
City Of Hope |
Insulin receptor binding site
|
|
EP0364690A3
(de)
*
|
1988-08-23 |
1990-07-18 |
Dana Farber Cancer Institute |
Alpha-Subeinheit des Mac-1-Leukocyt-Adhäsions-Rezeptors
|
|
US6277591B1
(en)
|
1988-11-18 |
2001-08-21 |
Oregon Health Science University |
Dopamine receptors and genes
|
|
US5217867A
(en)
*
|
1988-11-30 |
1993-06-08 |
The Salk Institute For Biological Studies |
Receptors: their identification, characterization, preparation and use
|
|
EP0452364B1
(de)
*
|
1988-12-22 |
2002-05-22 |
Genentech, Inc. |
Verfahren zur herstellung von wasserlöslichen polypeptiden
|
|
JPH04505103A
(ja)
*
|
1989-05-05 |
1992-09-10 |
ジェネンテク,インコーポレイテッド |
糖タンパク質ホルモン受容体分子
|
|
US6261800B1
(en)
|
1989-05-05 |
2001-07-17 |
Genentech, Inc. |
Luteinizing hormone/choriogonadotropin (LH/CG) receptor
|
|
US5073540A
(en)
*
|
1989-05-15 |
1991-12-17 |
Receptron |
Composite binding site drugs
|
|
DE69031120T2
(de)
|
1989-05-19 |
1998-01-15 |
Genentech, Inc., South San Francisco, Calif. |
Her2 extrazellulare domäne
|
|
CA2063431C
(en)
*
|
1989-07-06 |
2002-10-29 |
Lewis T. Williams |
Receptors for fibroblast growth factors
|
|
US5665543A
(en)
*
|
1989-07-18 |
1997-09-09 |
Oncogene Science, Inc. |
Method of discovering chemicals capable of functioning as gene expression modulators
|
|
US5580722A
(en)
*
|
1989-07-18 |
1996-12-03 |
Oncogene Science, Inc. |
Methods of determining chemicals that modulate transcriptionally expression of genes associated with cardiovascular disease
|
|
US5776502A
(en)
|
1989-07-18 |
1998-07-07 |
Oncogene Science, Inc. |
Methods of transcriptionally modulating gene expression
|
|
ATE238431T1
(de)
*
|
1989-07-18 |
2003-05-15 |
Osi Pharm Inc |
Methode der veränderung der expression von genen bei der transkription und zum nachweis von chemischen substanzen, die wie modulatoren der genexpression wirken
|
|
US6203976B1
(en)
*
|
1989-07-18 |
2001-03-20 |
Osi Pharmaceuticals, Inc. |
Methods of preparing compositions comprising chemicals capable of transcriptional modulation
|
|
US5215963A
(en)
*
|
1989-10-24 |
1993-06-01 |
Berlex Laboratories, Inc. |
Solubilization and purification of the active gastrin releasing peptide receptor
|
|
US6458360B1
(en)
|
1990-04-25 |
2002-10-01 |
The Johns Hopkins University |
Soluble complement regulatory molecules
|
|
US6265566B1
(en)
|
1990-08-17 |
2001-07-24 |
Immulogic Pharmaceuticals, Inc. |
Ryegrass pollen allergen
|
|
US5569601A
(en)
|
1990-12-07 |
1996-10-29 |
State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University |
Human dopamine receptor and its uses
|
|
WO1992013091A1
(en)
*
|
1991-01-18 |
1992-08-06 |
Oncogene Science, Inc. |
Methods of transcriptionally modulating expression of oncogenes and tumor suppressor genes
|
|
AU1469292A
(en)
*
|
1991-01-18 |
1992-08-27 |
Oncogene Science, Inc. |
Methods of transcriptionally modulating expression of growth factor genes and growth factor receptor genes
|
|
AU671417B2
(en)
|
1991-03-15 |
1996-08-29 |
Merck Serono Sa |
Human follicle stimulating hormone receptor
|
|
JPH07507441A
(ja)
*
|
1991-11-01 |
1995-08-24 |
ジヨスリン・ダイアビーテイス・センター |
1型真性糖尿病に関連する抗原
|
|
US5532347A
(en)
*
|
1992-04-10 |
1996-07-02 |
State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University, A Non-Profit Organization |
DNA encoding α melanocyte stimulating hormone receptor
|
|
US5280112A
(en)
*
|
1992-04-10 |
1994-01-18 |
State Of Oregon, Oregon Health Sciences University |
DNA sequence encoding bovine and human adrenocorticotropic hormone receptors
|
|
AU1812595A
(en)
*
|
1994-02-28 |
1995-09-11 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. |
Cell lines for the identification of substances affecting insulin receptor mediated signal transduction
|
|
AU2470295A
(en)
*
|
1994-05-06 |
1995-11-29 |
Nexstar Pharmaceuticals, Inc. |
High-affinity ligands of insulin receptor antibodies, tachykinin substance p, hiv integrase and hiv-1 reverse transcriptase
|
|
US8183344B2
(en)
*
|
1996-04-24 |
2012-05-22 |
University Of Michigan |
Inactivation resistant factor VIII
|
|
US6593456B1
(en)
*
|
1996-11-06 |
2003-07-15 |
The Regents Of The University Of California |
Tumor necrosis factor receptor releasing enzyme
|
|
US6930084B1
(en)
|
1996-11-06 |
2005-08-16 |
The Regents Of The University Of California |
Treating arthritis with TNF receptor releasing enzyme
|
|
EP1988165A1
(de)
|
1999-03-31 |
2008-11-05 |
The University of North Carolina at Chapel Hill |
Cullin-Regulator ROC1 zur Kodierung isolierter DNA, durch diesen Regulator kodierte isolierte Proteine und Verfahren zu seiner Verwendung
|
|
US6911314B2
(en)
|
1999-05-14 |
2005-06-28 |
The Regents Of The University Of California |
Screening for drugs that affect TNF receptor releasing enzyme
|
|
US7181349B1
(en)
|
1999-05-27 |
2007-02-20 |
Cecil Yip |
Identification of compounds for modulating dimeric receptors
|
|
US7101989B1
(en)
|
1999-07-09 |
2006-09-05 |
University Of North Carolina At Chapel Hill |
DsrA protein and polynucleotides encoding the same
|
|
GB9924717D0
(en)
*
|
1999-10-19 |
1999-12-22 |
Glaxo Group Ltd |
Diagnostic
|
|
CN105131104B
(zh)
|
2001-10-10 |
2018-11-16 |
诺和诺德公司 |
肽的重构和糖缀合
|
|
AU2004221824B2
(en)
|
2003-03-14 |
2009-08-27 |
Ratiopharm Gmbh |
Branched water-soluble polymers and their conjugates
|
|
SG155777A1
(en)
|
2003-04-09 |
2009-10-29 |
Neose Technologies Inc |
Glycopegylation methods and proteins/peptides produced by the methods
|
|
US7514593B2
(en)
|
2003-05-30 |
2009-04-07 |
The University Of North Carolina At Chapel Hill |
Animal model for chronic obstructive pulmonary disease and cystic fibrosis
|
|
CA2904275C
(en)
|
2004-05-23 |
2020-09-01 |
Gerard M. Housey |
Theramutein modulators
|
|
PL2586456T3
(pl)
|
2004-10-29 |
2016-07-29 |
Ratiopharm Gmbh |
Remodeling i glikopegilacja czynnika wzrostu fibroblastów (FGF)
|
|
EP1871795A4
(de)
|
2005-04-08 |
2010-03-31 |
Biogenerix Ag |
Zusammensetzungen und verfahren zur herstellung von glycosylierungsmutanten eines proteaseresistenten menschlichen wachstumshormons
|
|
US8431110B2
(en)
|
2005-05-23 |
2013-04-30 |
Hmi Medical Innovations, Llc. |
Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators
|
|
EP4424838A3
(de)
*
|
2005-11-23 |
2024-12-04 |
Gerard M. Housey |
Verbindungen und verfahren zur identifizierung, synthese, optimierung und profilerstellung von proteinmodulatoren
|
|
JP5526332B2
(ja)
|
2005-12-21 |
2014-06-18 |
シーエヌジェイ ホールディングス,インコーポレイテッド |
組み換え法によって生物活性ビタミンk依存性タンパク質を製造する方法
|
|
WO2007149010A1
(en)
|
2006-06-06 |
2007-12-27 |
Oleg Iliich Epshtein |
Medicinal agent for treating fatness, diabetes, and diseases associated with impaired glucose tolerance
|
|
WO2008005847A2
(en)
|
2006-06-30 |
2008-01-10 |
The Regents Of The University Of Michigan |
Method of producing factor viii proteins by recombinant methods
|
|
US20090203077A1
(en)
*
|
2006-06-30 |
2009-08-13 |
The Regents Of The University Of Michigan |
Method of producing factor viii proteins by recombinant methods
|
|
JP6050927B2
(ja)
|
2007-04-26 |
2016-12-21 |
シーエヌジェイ ホールディングス,インコーポレイテッド |
高シアル酸含量を有する組換えビタミンk依存性タンパク質およびその調製方法
|
|
CA2772945A1
(en)
|
2009-09-25 |
2011-03-31 |
Xoma Technology Ltd. |
Screening methods
|
|
US8926976B2
(en)
*
|
2009-09-25 |
2015-01-06 |
Xoma Technology Ltd. |
Modulators
|
|
EP2494040B1
(de)
|
2009-10-30 |
2018-08-29 |
Aptevo BioTherapeutics LLC |
Verfahren zur herstellung rekombinanter vitamin-k-abhängiger proteine
|
|
JP2015536148A
(ja)
|
2012-11-20 |
2015-12-21 |
ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル |
改変第ix因子タンパク質についての方法および組成物
|
|
CN107531774B
(zh)
|
2015-02-06 |
2021-12-14 |
北卡罗来纳大学查珀尔希尔分校 |
优化的人类凝血因子viii基因表达盒及其用途
|
|
WO2017070167A1
(en)
|
2015-10-20 |
2017-04-27 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for modified factor ix fusion proteins
|
|
JP2025525516A
(ja)
|
2022-07-12 |
2025-08-05 |
リシリアン ベー.フェー. |
高インスリン血症と関連する低血糖症を伴う状態の処置
|