ATE65696T1 - Verwendung von defibrotid bei der behandlung von zustaenden akuter nierenschwaeche. - Google Patents

Verwendung von defibrotid bei der behandlung von zustaenden akuter nierenschwaeche.

Info

Publication number
ATE65696T1
ATE65696T1 AT84201286T AT84201286T ATE65696T1 AT E65696 T1 ATE65696 T1 AT E65696T1 AT 84201286 T AT84201286 T AT 84201286T AT 84201286 T AT84201286 T AT 84201286T AT E65696 T1 ATE65696 T1 AT E65696T1
Authority
AT
Austria
Prior art keywords
defibrotid
treatment
kidney failure
acute kidney
failure conditions
Prior art date
Application number
AT84201286T
Other languages
German (de)
English (en)
Inventor
Vittorio Bonomini
Original Assignee
Crinos Industria Farmaco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crinos Industria Farmaco filed Critical Crinos Industria Farmaco
Application granted granted Critical
Publication of ATE65696T1 publication Critical patent/ATE65696T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT84201286T 1983-09-12 1984-09-07 Verwendung von defibrotid bei der behandlung von zustaenden akuter nierenschwaeche. ATE65696T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT22856/83A IT1170215B (it) 1983-09-12 1983-09-12 Composizione farmaceutica per il trattamento di stati di insufficienza renale acuta
EP84201286A EP0137542B1 (en) 1983-09-12 1984-09-07 Use of defibrotide in the treatment of states of acute renal insufficiency

Publications (1)

Publication Number Publication Date
ATE65696T1 true ATE65696T1 (de) 1991-08-15

Family

ID=11201234

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84201286T ATE65696T1 (de) 1983-09-12 1984-09-07 Verwendung von defibrotid bei der behandlung von zustaenden akuter nierenschwaeche.

Country Status (8)

Country Link
US (1) US4649134A (enExample)
EP (1) EP0137542B1 (enExample)
JP (1) JPH0647546B2 (enExample)
AT (1) ATE65696T1 (enExample)
BE (1) BE900563A (enExample)
CH (1) CH661871A5 (enExample)
DE (1) DE3433329A1 (enExample)
IT (1) IT1170215B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1170214B (it) * 1983-09-12 1987-06-03 Crinos Industria Farmaco Composizione farmaceutica per la cura delle arteriopatie periferiche
US5223609A (en) * 1986-04-17 1993-06-29 Crinos Industria Farmacobiologica S.P.A. Process for obtaining chemically defined and reproducible polydeoxyribonucleotides
IT1190313B (it) * 1986-04-17 1988-02-16 Crinos Industria Farmaco Procedimento per l'ottenimento di polidesossiribonucleotidi chimicamente definiti e riproducibili e prodotto farmacologicamente attivo risultante
IT1223322B (it) * 1987-10-23 1990-09-19 Crinos Industria Farmaco Metodo per prevenire la formazione di coaguli sanguigni nel circuito extracorporeo di apparecchi di dialisi a composizione utile per esso
IT1231509B (it) * 1989-09-07 1991-12-07 Crinos Industria Farmaco Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.
US6699985B2 (en) * 1991-08-21 2004-03-02 Arsinur Burcoglu Method of treating HIV infection and related secondary infections thereof
US5977083A (en) * 1991-08-21 1999-11-02 Burcoglu; Arsinur Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
US5624912A (en) * 1991-08-21 1997-04-29 Burcoglu; Arsinur Method of treating HIV infection and related secondary infections with defibrotide
CA2153778C (en) * 1993-01-13 2004-07-06 Arsinur Burcoglu Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
HK1044896A1 (zh) * 1997-04-28 2002-11-08 Burcoglu Arsinur 治疗hiv感染和与之有关的继发感染的方法
EP1325962A1 (en) * 2001-12-17 2003-07-09 Gentium S.p.A. A method for determining the biological activity of defibrotide
EP1872787A1 (en) * 2006-06-27 2008-01-02 Gentium S.p.A. Use of defibrotide for the inhibition of heparanase
EP1982722A1 (en) * 2007-04-16 2008-10-22 Gentium S.p.A. Use of oligotide for the treatment of renal diseases
US8515557B2 (en) 2007-11-19 2013-08-20 Cochlear Limited Electrode array for a cochlear implant
EP2103689A1 (en) * 2008-03-19 2009-09-23 Gentium S.p.A. Synthetic phosphodiester oligonucleotides and therapeutical uses thereof
IT1406068B1 (it) 2010-07-22 2014-02-06 Medestea Int Spa Polidesossiribonucleotidi (pdrn) per l'impiego nel trattamento di condizioni di acidosi e composizioni a base di polidesossiribonucleotidi per il suddetto impiego
EP2637672B1 (en) 2010-11-12 2018-08-22 Gentium S.r.l. Defibrotide for use in prophylaxis and/or treatment of graft versus host disease (gvhd).
DK2864496T4 (da) * 2012-06-22 2021-01-04 Gentium S R L Euglobulin-baseret fremgangsmåde til bestemmelse af den biologiske aktivitet af defibrotid
EP3026122A1 (en) 2014-11-27 2016-06-01 Gentium S.p.A. Cellular-based method for determining the potency of defibrotide
RU2766143C2 (ru) * 2017-07-26 2022-02-08 Джентиум С.Р.Л. Жидкая композиция дефибротида для лечения и профилактики веноокклюзионной болезни
MX2020001337A (es) * 2017-08-03 2020-09-09 Jazz Pharmaceuticals Ireland Ltd Formulaciones que comprenden un acido nucleico en una alta concentracion.
KR20210008478A (ko) 2018-04-12 2021-01-22 재즈 파마슈티칼즈, 인코포레이티드 면역고갈과 관련된 사이토카인 방출 증후군 및 신경독성의 예방 및 치료를 위한 데피브로타이드
WO2021212055A1 (en) 2020-04-17 2021-10-21 Jazz Pharmaceuticals Ireland Limited Defibrotide treatment for the prevention of organ rejection and injury
WO2022234101A1 (en) 2021-05-06 2022-11-10 Jazz Pharmaceuticals Ireland Limited Defibrotide for the treatment and prevention of acute respiratory distress syndrome

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB879622A (en) * 1959-07-13 1961-10-11 Farmaceutici Italia Steroids
DE1202439B (de) * 1959-11-24 1965-10-07 Cediap Centrale De Destributio Verfahren zur Herstellung von Praeparaten mit hohem Gehalt an freien Desoxyribonucleinsaeuren aus Fischmilch
FR2575M (fr) * 1962-03-19 1964-06-08 Cediap Centrale De Distrib D A Procédé de préparation d'un médicament a base d'adn (acide désoxyribonucléique) en milieu vital d'origine et produit nouveau en résultant.
DE2154279A1 (de) * 1970-11-03 1972-05-25 Crinos Industria Farmaco Medikamente für das fibrinolytische System
IT1043823B (it) * 1970-11-03 1980-02-29 Prephar Procedimento per l estrazione di acidi nucleici da organi animali
US3899481A (en) * 1970-11-03 1975-08-12 Crinos Industria Farmaco Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs

Also Published As

Publication number Publication date
JPH0647546B2 (ja) 1994-06-22
IT8322856A0 (it) 1983-09-12
JPS6084224A (ja) 1985-05-13
CH661871A5 (it) 1987-08-31
EP0137542B1 (en) 1991-07-31
IT1170215B (it) 1987-06-03
EP0137542A2 (en) 1985-04-17
US4649134A (en) 1987-03-10
BE900563A (fr) 1985-01-02
DE3433329A1 (de) 1985-03-28
EP0137542A3 (en) 1987-09-02
DE3433329C2 (enExample) 1993-07-22

Similar Documents

Publication Publication Date Title
ATE65696T1 (de) Verwendung von defibrotid bei der behandlung von zustaenden akuter nierenschwaeche.
DE3885300D1 (de) Heilen von wunden.
DE3689974D1 (de) Arzneimittel zur Behandlung von Emesis.
UA19303A (uk) Спосіб одержаhhя похідhих 2-аhіліhопіримідиhу
NL971024I1 (nl) Acrylzuuramiden, hun bereiding en hun toepassing als fungiciden.
NL7706684A (nl) Anti-aritmie hartstimulator.
IS1565B (is) Aðferð við framleiðslu á N1-súbstitúeruðum bensimidasólafleiðum til að nota við lækningar
ATE16489T1 (de) Aroylimidazolone.
IT7821466A0 (it) Complessi di ammino-acido-acido mandelico otticamente attivi erelativo al procedimento di preparazione.
DE3670310D1 (de) Elektrochemische behandlung von ligninen.
FR2545825B1 (fr) 1-pyrimidinyloxy-3-hetarylalkylamino-2-propanols, leur preparation et leurs utilisations therapeutiques
FI802676A7 (fi) 6-pyridatsinoneja ja sydänlääkkeenä käytettävä valmiste.
DE3482333D1 (de) Zahnbauart zur vermeidung von scherbeanspruchungen.
DE3574674D1 (de) Mischung von 2-substituierten carbapenemen mit dipeptidase-inhibitoren.
IT1164915B (it) Trifluoroetil-ammine sostituite, procedimento per ottenerle e farmaci che le contengono
CH481572A (de) Substituierte Furancarbonsäureanilide enthaltendes Fungizid, dessen Herstellung und Verwendung
LU81369A1 (de) Lagerbestaendige,schnell wirkende tablette zur bekaempfung von ueberwiegend in unterirdischen bauen lebenden wirbeltieren
CA961041A (en) 1-methyl-3-alkoxymethyl-5,5-disub-stituted barbituric acid compounds and therapeutic compositions containing same
MX9203782A (es) Forma de dosis con capacidad de administracion mejorada.
FI834362A7 (fi) Korkean verenpaineen hoitoon käytettäviä yhdisteitä.
DE3686472D1 (de) Cardiotonische phenyloxazolone.
FI862493A0 (fi) Fysiologiska medel foer effektivering av transdermal administration av laekemedel.
IT1170361B (it) Cianoguanidine, procedimento per ottenerle e composizioni farmaceutiche che le contengono
IT8720800A0 (it) Composto attivo nella terapia carciovascolare.
ATA208581A (de) Wirkdruckzumischgeraet

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties