ATE57186T1 - Imidazolylthienobenzothiepin-derivate und verfahren zu ihrer herstellung. - Google Patents
Imidazolylthienobenzothiepin-derivate und verfahren zu ihrer herstellung.Info
- Publication number
- ATE57186T1 ATE57186T1 AT86308622T AT86308622T ATE57186T1 AT E57186 T1 ATE57186 T1 AT E57186T1 AT 86308622 T AT86308622 T AT 86308622T AT 86308622 T AT86308622 T AT 86308622T AT E57186 T1 ATE57186 T1 AT E57186T1
- Authority
- AT
- Austria
- Prior art keywords
- thieno
- benzothiepin
- imidazole
- derivatives
- imidazolylthienobenzothiepine
- Prior art date
Links
- UBNRYQRJBJFNIV-UHFFFAOYSA-N 2-thieno[2,3-i][1]benzothiepin-2-yl-1h-imidazole Chemical class S1C(C=2C=CSC=2C=C2)=C2C=CC=C1C1=NC=CN1 UBNRYQRJBJFNIV-UHFFFAOYSA-N 0.000 title abstract 2
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 2
- DWSJLOMKKVCTPJ-UHFFFAOYSA-N 5,10-dihydrothieno[2,3-c][2]benzothiepin-10-ol Chemical compound S1CC2=CC=CC=C2C(O)C2=C1SC=C2 DWSJLOMKKVCTPJ-UHFFFAOYSA-N 0.000 abstract 1
- 208000031888 Mycoses Diseases 0.000 abstract 1
- 239000002253 acid Chemical group 0.000 abstract 1
- 230000001857 anti-mycotic effect Effects 0.000 abstract 1
- 229910052801 chlorine Chemical group 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 230000002500 effect on skin Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS858664A CS250579B1 (en) | 1985-11-29 | 1985-11-29 | Imidazole derivatives and method of their preparation |
| EP86308622A EP0226320B1 (de) | 1985-11-29 | 1986-11-05 | Imidazolylthienobenzothiepin-Derivate und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE57186T1 true ATE57186T1 (de) | 1990-10-15 |
Family
ID=5437511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86308622T ATE57186T1 (de) | 1985-11-29 | 1986-11-05 | Imidazolylthienobenzothiepin-derivate und verfahren zu ihrer herstellung. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4730054A (de) |
| EP (1) | EP0226320B1 (de) |
| JP (1) | JPS62132885A (de) |
| AT (1) | ATE57186T1 (de) |
| CA (1) | CA1278297C (de) |
| CS (1) | CS250579B1 (de) |
| DE (1) | DE3674741D1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5631210A (en) * | 1996-06-14 | 1997-05-20 | E. I. Du Pont De Nemours And Company | Herbicidal thiophene ketones |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1081360A (en) * | 1965-08-25 | 1967-08-31 | Spofa Vereinigte Pharma Werke | Novel 4-substituted-4,5-dihydrothieno-(2,3-b)-benzo(f)thiepines and process for the preparation thereof |
| US4169205A (en) * | 1978-10-25 | 1979-09-25 | E. R. Squibb & Sons, Inc. | Imidazole derivatives of 6,11-dihydrodibenz[b,e]oxepines and 6,11-dihydrodibenz[b,e]thiepines |
-
1985
- 1985-11-29 CS CS858664A patent/CS250579B1/cs unknown
-
1986
- 1986-11-05 DE DE8686308622T patent/DE3674741D1/de not_active Expired - Fee Related
- 1986-11-05 EP EP86308622A patent/EP0226320B1/de not_active Expired - Lifetime
- 1986-11-05 AT AT86308622T patent/ATE57186T1/de active
- 1986-11-05 CA CA000522256A patent/CA1278297C/en not_active Expired - Fee Related
- 1986-11-28 JP JP61282172A patent/JPS62132885A/ja active Pending
- 1986-12-01 US US06/936,540 patent/US4730054A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3674741D1 (de) | 1990-11-08 |
| EP0226320A1 (de) | 1987-06-24 |
| CA1278297C (en) | 1990-12-27 |
| US4730054A (en) | 1988-03-08 |
| JPS62132885A (ja) | 1987-06-16 |
| EP0226320B1 (de) | 1990-10-03 |
| CS250579B1 (en) | 1987-04-16 |
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