ATE552002T1 - Feste zubereitung zur oralen verabreichung - Google Patents
Feste zubereitung zur oralen verabreichungInfo
- Publication number
- ATE552002T1 ATE552002T1 AT09712557T AT09712557T ATE552002T1 AT E552002 T1 ATE552002 T1 AT E552002T1 AT 09712557 T AT09712557 T AT 09712557T AT 09712557 T AT09712557 T AT 09712557T AT E552002 T1 ATE552002 T1 AT E552002T1
- Authority
- AT
- Austria
- Prior art keywords
- oral administration
- solid preparation
- cariprazine hydrochloride
- lactose
- enables
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008040696 | 2008-02-21 | ||
| JP2008284685 | 2008-11-05 | ||
| PCT/JP2009/053039 WO2009104739A1 (ja) | 2008-02-21 | 2009-02-20 | 経口投与用固形製剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE552002T1 true ATE552002T1 (de) | 2012-04-15 |
Family
ID=40985616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT09712557T ATE552002T1 (de) | 2008-02-21 | 2009-02-20 | Feste zubereitung zur oralen verabreichung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20110059980A1 (https=) |
| EP (1) | EP2251011B1 (https=) |
| JP (2) | JP4409630B2 (https=) |
| KR (2) | KR101563383B1 (https=) |
| CN (1) | CN102014909B (https=) |
| AT (1) | ATE552002T1 (https=) |
| CA (1) | CA2715760C (https=) |
| EA (1) | EA023972B1 (https=) |
| WO (1) | WO2009104739A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0700353A2 (en) * | 2007-05-18 | 2008-12-29 | Richter Gedeon Nyrt | Metabolites of (thio)carbamoyl-cyclohexane derivatives |
| US7875610B2 (en) * | 2007-12-03 | 2011-01-25 | Richter Gedeon Nyrt. | Pyrimidinyl-piperazines useful as D3/D2 receptor ligands |
| KR101563383B1 (ko) * | 2008-02-21 | 2015-10-26 | 미쓰비시 타나베 파마 코퍼레이션 | 경구 투여용 고형 제제 |
| PL2317852T3 (pl) * | 2008-07-16 | 2015-05-29 | Richter Gedeon Nyrt | Preparaty farmaceutyczne zawierające ligandy receptora dopaminy |
| HU230067B1 (hu) | 2008-12-17 | 2015-06-29 | Richter Gedeon Nyrt | Új piperazin só és eljárás előállítására |
| HUP0800765A2 (en) | 2008-12-18 | 2010-11-29 | Richter Gedeon Nyrt | A new process for the preparation of piperazine derivatives and their hydrochloric salts |
| HUP0800766A2 (en) | 2008-12-18 | 2010-11-29 | Richter Gedeon Vegyeszet | Process for the preparation of piperazine derivatives |
| CN106560179B (zh) * | 2015-09-30 | 2020-02-21 | 石药集团中奇制药技术（石家庄）有限公司 | 盐酸卡利拉嗪药物组合物及其制备方法 |
| EP3231418A1 (en) * | 2016-04-14 | 2017-10-18 | Richter Gedeon Nyrt. | Granule formulation for oral administration |
| JP7020688B2 (ja) * | 2016-06-28 | 2022-02-16 | 株式会社日本抗菌総合研究所 | 賦形剤及び錠剤 |
| US11274087B2 (en) | 2016-07-08 | 2022-03-15 | Richter Gedeon Nyrt. | Industrial process for the preparation of cariprazine |
| CN107970217A (zh) * | 2016-10-25 | 2018-05-01 | 浙江京新药业股份有限公司 | 卡利拉嗪口腔崩解片及其制备方法 |
| CN108261394B (zh) * | 2017-01-04 | 2022-03-04 | 广东东阳光药业有限公司 | 一种盐酸卡利拉嗪注射制剂及其制备方法和用途 |
| HUP1700253A1 (hu) * | 2017-06-13 | 2019-01-28 | Richter Gedeon Nyrt | Szilárd orális gyógyszerkészítmények |
| US11273156B2 (en) * | 2018-11-20 | 2022-03-15 | Aurobindo Pharma Ltd | Stable cariprazine formulations for oral use |
| US11547707B2 (en) | 2019-04-10 | 2023-01-10 | Richter Gedeon Nyrt. | Carbamoyl cyclohexane derivatives for treating autism spectrum disorder |
| US11344503B2 (en) * | 2019-12-13 | 2022-05-31 | Halo Science LLC | Cariprazine release formulations |
| US20230338295A1 (en) * | 2020-08-06 | 2023-10-26 | Sk Biopharmaceuticals Co., Ltd. | Solid oral composition comprising carbamate compound, and preparation method therefor |
| CN118526462B (zh) * | 2024-07-25 | 2024-11-15 | 山东则正医药技术有限公司 | 不同规格溶出行为相似的盐酸卡利拉嗪口崩片及制备方法 |
| TR2024011970A1 (tr) * | 2024-09-10 | 2026-03-23 | Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ | Kari̇prazi̇n hi̇droklorür i̇çeren kati bi̇r oral bi̇leşi̇m |
| TR2024011969A1 (tr) | 2024-09-10 | 2026-03-23 | Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ | Kari̇prazi̇n hi̇droklorür i̇çeren bi̇r kapsül formülasyonu |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4666911A (en) * | 1981-07-14 | 1987-05-19 | Taiho Pharmaceutical Company Limited | Allophanoylpiperazine compound and analgesic composition containing same as active ingredient |
| GB8802622D0 (en) * | 1988-02-05 | 1988-03-02 | Glaxo Group Ltd | Chemical compound |
| US4957921A (en) * | 1989-12-06 | 1990-09-18 | Warner-Lambert Company | Substituted cyclohexanols as central nervous system agents |
| US6334997B1 (en) * | 1994-03-25 | 2002-01-01 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| CN1087725C (zh) * | 1994-03-25 | 2002-07-17 | 同位素技术有限公司 | 用氘代方法增强药物效果 |
| US6528529B1 (en) * | 1998-03-31 | 2003-03-04 | Acadia Pharmaceuticals Inc. | Compounds with activity on muscarinic receptors |
| US6395739B1 (en) * | 1998-06-30 | 2002-05-28 | Zeria Pharmaceutical Co., Ltd. | N-phenyl-N′-phenylpopylpiperazine derivatives and process for the preparation |
| US6489341B1 (en) * | 1999-06-02 | 2002-12-03 | Sepracor Inc. | Methods for the treatment of neuroleptic and related disorders using sertindole derivatives |
| US7122576B2 (en) * | 2001-02-27 | 2006-10-17 | Plata-Salaman Carlos R | Carbamate compounds for use in preventing or treating bipolar disorder |
| US6566550B2 (en) * | 2001-06-21 | 2003-05-20 | Pfizer Inc | Substituted aromatic ethers as inhibitors of glycine transport |
| HU227543B1 (en) * | 2001-09-28 | 2011-08-29 | Richter Gedeon Nyrt | N-[4-(2-piperazin- and 2-piperidin-1-yl-ethyl)-cyclohexyl]-sulfon- and sulfamides, process for their preparation, their use and pharmaceutical compositions containing them |
| US6919342B2 (en) * | 2003-06-05 | 2005-07-19 | Abbott Gmbh & Co. Kg | Triazole compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor |
| HU227534B1 (en) * | 2003-08-04 | 2011-08-29 | Richter Gedeon Nyrt | (thio)carbamoyl-cyclohexane derivatives, process for producing them and pharmaceutical compositions containing them |
| DE102004047517A1 (de) * | 2004-09-28 | 2006-03-30 | Merck Patent Gmbh | Neuartige Kristallform von (3-Cyan-1H-indol-7-yl)-[4-(4-fluorphenethyl)-piperazin-1-yl]-methanon, Hydrochlorid |
| ES2617671T3 (es) * | 2007-05-11 | 2017-06-19 | Richter Gedeon Nyrt. | Forma cristalina de un derivado de carbamoil ciclohexano |
| HU230748B1 (hu) * | 2007-05-11 | 2018-02-28 | Richter Gedeon Nyrt | Új piperazin só és előállítási eljárása |
| HUP0700353A2 (en) * | 2007-05-18 | 2008-12-29 | Richter Gedeon Nyrt | Metabolites of (thio)carbamoyl-cyclohexane derivatives |
| HUP0700369A2 (en) * | 2007-05-24 | 2009-04-28 | Richter Gedeon Nyrt | Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment in the manufacture of a medicament for the treatment of schizophrenia |
| HUP0700370A2 (en) * | 2007-05-24 | 2009-04-28 | Richter Gedeon Nyrt | Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment of acute mania |
| CN101790374A (zh) * | 2007-08-01 | 2010-07-28 | H.隆德贝克有限公司 | Kcnq钾通道开放剂用于减轻多巴胺能系统受到干扰的障碍或病症的症状或治疗这种障碍或病症的用途 |
| US7875610B2 (en) * | 2007-12-03 | 2011-01-25 | Richter Gedeon Nyrt. | Pyrimidinyl-piperazines useful as D3/D2 receptor ligands |
| KR101563383B1 (ko) * | 2008-02-21 | 2015-10-26 | 미쓰비시 타나베 파마 코퍼레이션 | 경구 투여용 고형 제제 |
| PL2317852T3 (pl) * | 2008-07-16 | 2015-05-29 | Richter Gedeon Nyrt | Preparaty farmaceutyczne zawierające ligandy receptora dopaminy |
| HU230067B1 (hu) * | 2008-12-17 | 2015-06-29 | Richter Gedeon Nyrt | Új piperazin só és eljárás előállítására |
| HUP0800765A2 (en) * | 2008-12-18 | 2010-11-29 | Richter Gedeon Nyrt | A new process for the preparation of piperazine derivatives and their hydrochloric salts |
| HUP0800766A2 (en) * | 2008-12-18 | 2010-11-29 | Richter Gedeon Vegyeszet | Process for the preparation of piperazine derivatives |
-
2009
- 2009-02-20 KR KR1020107020649A patent/KR101563383B1/ko active Active
- 2009-02-20 CN CN2009801148592A patent/CN102014909B/zh active Active
- 2009-02-20 EP EP09712557A patent/EP2251011B1/en active Active
- 2009-02-20 EA EA201001334A patent/EA023972B1/ru unknown
- 2009-02-20 AT AT09712557T patent/ATE552002T1/de active
- 2009-02-20 WO PCT/JP2009/053039 patent/WO2009104739A1/ja not_active Ceased
- 2009-02-20 US US12/918,580 patent/US20110059980A1/en not_active Abandoned
- 2009-02-20 KR KR1020137025458A patent/KR20130115393A/ko not_active Ceased
- 2009-02-20 CA CA2715760A patent/CA2715760C/en not_active Expired - Fee Related
- 2009-02-20 JP JP2009520724A patent/JP4409630B2/ja active Active
- 2009-11-11 JP JP2009258219A patent/JP2010132654A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20130115393A (ko) | 2013-10-21 |
| EA201001334A1 (ru) | 2011-06-30 |
| JP2010132654A (ja) | 2010-06-17 |
| US20110059980A1 (en) | 2011-03-10 |
| EP2251011A4 (en) | 2011-03-02 |
| EA023972B1 (ru) | 2016-08-31 |
| CA2715760C (en) | 2017-06-13 |
| KR20100117676A (ko) | 2010-11-03 |
| CN102014909A (zh) | 2011-04-13 |
| JP4409630B2 (ja) | 2010-02-03 |
| CA2715760A1 (en) | 2009-08-27 |
| EP2251011B1 (en) | 2012-04-04 |
| KR101563383B1 (ko) | 2015-10-26 |
| EP2251011A1 (en) | 2010-11-17 |
| WO2009104739A1 (ja) | 2009-08-27 |
| CN102014909B (zh) | 2013-03-13 |
| JPWO2009104739A1 (ja) | 2011-06-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE552002T1 (de) | Feste zubereitung zur oralen verabreichung | |
| HUS000504I2 (hu) | Relebaktám, adott esetben monohidrát formájában, és imipenem kombinációja | |
| EA200701065A1 (ru) | Инъецируемые составы, содержащие нанодисперсный оланзапин | |
| EA201100358A1 (ru) | Дабигатран для чрескожной хирургической катетеризации сердца | |
| BRPI0913379A2 (pt) | formulações farmacêuticas sólidas compreendendo bibw 2992 | |
| EA201170512A1 (ru) | Композиция для перорального введения | |
| EA201200390A1 (ru) | Макроциклические ингибиторы сериновых протеаз гепатита с | |
| BRPI0906020A2 (pt) | Sais farmaceuticamente aceitáveis de 2-{4-[ (3s) - piperidina-3-il ] fenil} -2h - indazol - 7 - carboxamida, uso e método de tratamento | |
| MX2018013333A (es) | Composiciones de nucleasas terapeuticas y metodos. | |
| BRPI0916689A2 (pt) | composição farmacêutica estabilizada, preparação sólida, e, métodos para estabilizar uma composição farmacêutica, e para estabilizar uma preparação sólida. | |
| IL211028A0 (en) | Linaclotide-containing formulations for oral administration | |
| EA201290116A1 (ru) | Новые композиции 1-[2-(2,4-диметилфенилсульфанил)фенил]пиперазина | |
| ATE516044T1 (de) | Attenuierte rotavirus-vakzine zur oralen verabreichung | |
| PT2868315T (pt) | Formulações melhoradas e métodos para liofilização e liofilizados assim produzidos | |
| NO20075111L (no) | Farmasoytisk sammensetning | |
| WO2009149056A3 (en) | Combinations of niacin and an oxicam | |
| BR112015002183A2 (pt) | processos para a preparação de (s) -3- (4 - ((4- (morfolinometil) benzil) oxi) -1-oxoisoindolin-2-il) -piperidina-2,6-diona e formas farmaceuticamente aceitáveis da mesma | |
| UA109037C2 (uk) | Триазолопіридини | |
| WO2010055119A3 (en) | Pharmaceutical composition comprising pimobendan | |
| UA97660C2 (ru) | Жидкие композиции солей 4-[2-(4-метилфенилсульфанил)фенил]-пиперидина | |
| MX2010003989A (es) | Composicion zibotentan que contiene mannitol y/o celulosa microcristalina. | |
| EP2062579A4 (en) | SOLID PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING OPTICALLY STABLE RAMOSETRON | |
| BRPI0918539A2 (pt) | preparação farmacêutica sólida para administração oral | |
| CY1119315T1 (el) | Στερεες μορφες που περιεχουν μελοξικαμη με βελτιωμενη στοματικη γευση και η διαδικασια για τηn προετοιμασια τους | |
| TR201109686T2 (tr) | Olmesartan'ın Farmasötik Bileşimleri. |