ATE546521T1 - Sesquiterpene synthasen und verwerdungsmethoden - Google Patents

Sesquiterpene synthasen und verwerdungsmethoden

Info

Publication number
ATE546521T1
ATE546521T1 AT03769780T AT03769780T ATE546521T1 AT E546521 T1 ATE546521 T1 AT E546521T1 AT 03769780 T AT03769780 T AT 03769780T AT 03769780 T AT03769780 T AT 03769780T AT E546521 T1 ATE546521 T1 AT E546521T1
Authority
AT
Austria
Prior art keywords
sesquiterpene synthases
methods
sesquiterpene
synthases
provides
Prior art date
Application number
AT03769780T
Other languages
German (de)
English (en)
Inventor
Michel Schalk
Anthony Clark
Original Assignee
Firmenich & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Firmenich & Cie filed Critical Firmenich & Cie
Application granted granted Critical
Publication of ATE546521T1 publication Critical patent/ATE546521T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT03769780T 2002-10-04 2003-10-02 Sesquiterpene synthasen und verwerdungsmethoden ATE546521T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41576502P 2002-10-04 2002-10-04
IB0205070 2002-12-02
PCT/IB2003/005072 WO2004031376A2 (en) 2002-10-04 2003-10-02 Sesquiterpene synthases and methods of use

Publications (1)

Publication Number Publication Date
ATE546521T1 true ATE546521T1 (de) 2012-03-15

Family

ID=34590004

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03769780T ATE546521T1 (de) 2002-10-04 2003-10-02 Sesquiterpene synthasen und verwerdungsmethoden

Country Status (9)

Country Link
EP (3) EP1554379B1 (https=)
JP (1) JP4571862B2 (https=)
CN (3) CN1703507B (https=)
AT (1) ATE546521T1 (https=)
AU (1) AU2003278478A1 (https=)
BR (1) BR0314979A (https=)
IL (1) IL167832A (https=)
RU (1) RU2005113300A (https=)
WO (1) WO2004031376A2 (https=)

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US8106260B2 (en) 1996-04-12 2012-01-31 The Board Of Trustees Of The University Of Kentucky Chimeric isoprenoid synthases and uses thereof
US7442785B2 (en) 2003-07-24 2008-10-28 The University Of Kentucky Research Foundation Sesquiterpene synthase gene and protein
JP2007517496A (ja) * 2003-09-02 2007-07-05 ステート オブ イスラエル、ミニストリー オブ アグリカルチャー、 アグリカルチュラル リサーチ オーガナイゼイション 柑橘類セスキテルペンシンターゼ、その生成方法、及び使用方法
EP1874934B1 (en) 2005-04-19 2013-11-27 University of Kentucky Research Foundation Transformed plants accumulating terpenes
EP1893753B1 (en) 2005-06-17 2015-12-23 Firmenich Sa Novel sesquiterpene synthases and methods of their use
WO2007004104A2 (en) 2005-07-01 2007-01-11 University Of Kentucky Research Foundation Transformed plants accumulating mono- and/or sesquiterpenes
WO2008100251A1 (en) * 2007-02-13 2008-08-21 Ls9, Inc. Modified microorganism uses therefor
US8048658B2 (en) * 2006-02-14 2011-11-01 Firmenich Sa Method for producing terpenes and MEP-transformed microorganisms therefore
US20100242345A1 (en) 2006-05-19 2010-09-30 LS9, Inc Production of fatty acids & derivatives thereof
US8110670B2 (en) 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
CN101978062B (zh) * 2008-03-06 2014-04-02 弗门尼舍有限公司 用于生产α-檀香萜的方法
US8609371B2 (en) 2008-08-12 2013-12-17 Allylix, Inc. Isoprenoid compounds
EP2373790B1 (en) * 2008-12-05 2015-02-11 Keygene N.V. Farnesene synthase
BRPI1015313B1 (pt) 2009-04-27 2021-06-01 Genomatica, Inc. Método fermentativo para produzir um éster de ácido graxo empregando um microorganismo geneticamente modificado e método para a produção de ésteres de ácidos graxos
CA2766810C (en) 2009-06-29 2017-10-10 The University Of Western Australia Terpene synthases from santalum
CN102933084B (zh) 2009-10-28 2014-12-31 柑橘病虫害预防基金会 控制黄龙病的驱虫剂组合物和基因方法
EP2569427B1 (en) * 2010-05-10 2017-11-08 Firmenich SA Method for producing patchoulol and 7-epi-alpha-selinene
CN103282492A (zh) * 2010-10-29 2013-09-04 奥利里克斯股份有限公司 修饰的瓦伦烯合酶多肽、编码核酸分子及其用途
EP2537926A1 (en) * 2011-06-21 2012-12-26 Isobionics B.V. Valencene synthase
US20150059018A1 (en) 2011-10-19 2015-02-26 Keygene N.V. Methods and compositions for producing drimenol
US9550815B2 (en) 2012-01-23 2017-01-24 University Of British Columbia ABC terpenoid transporters and methods of using the same
CN103243083B (zh) * 2012-02-06 2015-06-03 中国科学院上海生命科学研究院 一种新的倍半萜合成酶及其用途
EP2970934B1 (en) 2013-03-14 2017-08-16 Evolva, Inc. Valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
ES2540791B1 (es) * 2013-12-13 2016-05-09 Consejo Superior De Investigaciones Científicas (Csic) Nuevas sesquiterpeno sintasas aisladas de la piel de naranja.
US10501760B2 (en) * 2014-08-21 2019-12-10 Givaudan Sa Methods for production of oxygenated terpenes
EP3371304B1 (en) * 2015-11-05 2021-01-06 Firmenich SA Drimenol synthases iii
CN105524908B (zh) * 2016-02-04 2018-12-28 中国农业科学院植物保护研究所 一种与(E)-β-石竹烯和(E)-a-律草烯合成相关的蛋白及其应用
CN110093329B (zh) * 2018-01-30 2023-07-04 深圳艾格鑫科技有限公司 萜类合酶及其应用
CN108977426B (zh) * 2018-06-29 2020-08-14 中国林业科学研究院热带林业研究所 一种油楠倍半萜合成酶及其编码基因和应用
CN109852600B (zh) * 2018-12-25 2021-12-31 天津大学 一种小萼苔倍半萜合成酶MTb及其基因序列
CN109837266B (zh) * 2019-01-24 2021-12-31 天津大学 一种小萼苔倍半萜合成酶MTc及其基因序列
CN109666668B (zh) * 2019-01-24 2022-04-15 天津大学 一种小萼苔倍半萜合成酶MTa及其基因序列
CN109929828A (zh) * 2019-01-30 2019-06-25 天津大学 一种苦皮藤倍半萜合成酶CaTPS1及其基因序列
CN111004763B (zh) * 2019-12-26 2022-06-03 中国科学院青岛生物能源与过程研究所 一种生产β-石竹烯的工程菌及其构建方法与应用
CN115404228B (zh) * 2021-05-28 2024-03-08 中国中医科学院中药研究所 山沉香倍半萜合酶蛋白tps1及其编码基因和应用
CN116004490A (zh) * 2022-07-12 2023-04-25 华东理工大学 一种生物合成右旋-双环吉玛烯的重组大肠杆菌、构建方法及应用
CN116555238B (zh) * 2023-06-09 2023-10-20 中国中医科学院中药研究所 SoSTPS1在作为倍半萜合酶中的应用
CN117126835B (zh) * 2023-08-11 2025-04-25 武汉合生科技有限公司 瓦伦烯合成酶及其应用
CN119899828B (zh) * 2025-01-17 2026-01-30 中国药科大学 利用SsDMS突变体高效生产新颖drimane型倍半萜化合物

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ZA811368B (en) 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
NZ201705A (en) 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
US4737462A (en) 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US4518584A (en) 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
US5990387A (en) 1988-06-10 1999-11-23 Pioneer Hi-Bred International, Inc. Stable transformation of plant cells
ATE341224T1 (de) * 1999-03-31 2006-10-15 Firmenich & Cie Verwendung von cubebol als aromastoff

Also Published As

Publication number Publication date
RU2005113300A (ru) 2005-10-27
EP1554379A2 (en) 2005-07-20
EP2365070A1 (en) 2011-09-14
EP3109319A1 (en) 2016-12-28
JP2006500942A (ja) 2006-01-12
EP2365070B1 (en) 2016-09-14
CN101914559A (zh) 2010-12-15
CN101914558B (zh) 2013-05-29
WO2004031376A3 (en) 2005-05-26
CN101914559B (zh) 2012-04-04
CN1703507B (zh) 2010-09-29
AU2003278478A8 (en) 2004-04-23
JP4571862B2 (ja) 2010-10-27
IL167832A (en) 2010-11-30
AU2003278478A1 (en) 2004-04-23
EP1554379B1 (en) 2012-02-22
WO2004031376A2 (en) 2004-04-15
BR0314979A (pt) 2005-08-02
CN1703507A (zh) 2005-11-30
CN101914558A (zh) 2010-12-15

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