CN1703507B - 倍半萜烯合成酶及其使用方法 - Google Patents

倍半萜烯合成酶及其使用方法 Download PDF

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Publication number
CN1703507B
CN1703507B CN2003801009412A CN200380100941A CN1703507B CN 1703507 B CN1703507 B CN 1703507B CN 2003801009412 A CN2003801009412 A CN 2003801009412A CN 200380100941 A CN200380100941 A CN 200380100941A CN 1703507 B CN1703507 B CN 1703507B
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seq
nucleic acid
polypeptide
nucleotide sequence
microorganism
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CN1703507A (zh
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米歇尔·沙尔克
安东尼·克拉克
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Firmenich SA
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
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  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
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  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN2003801009412A 2002-10-04 2003-10-02 倍半萜烯合成酶及其使用方法 Expired - Fee Related CN1703507B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41576502P 2002-10-04 2002-10-04
US60/415,765 2002-10-04
IB0205070 2002-12-02
WOPCT/IB02/05070 2002-12-02
PCT/IB2003/005072 WO2004031376A2 (en) 2002-10-04 2003-10-02 Sesquiterpene synthases and methods of use

Related Child Applications (2)

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CN2010102391730A Division CN101914558B (zh) 2002-10-04 2003-10-02 倍半萜烯合成酶及其使用方法
CN2010102392305A Division CN101914559B (zh) 2002-10-04 2003-10-02 倍半萜烯合成酶及其使用方法

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CN1703507A CN1703507A (zh) 2005-11-30
CN1703507B true CN1703507B (zh) 2010-09-29

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CN2003801009412A Expired - Fee Related CN1703507B (zh) 2002-10-04 2003-10-02 倍半萜烯合成酶及其使用方法
CN2010102392305A Expired - Fee Related CN101914559B (zh) 2002-10-04 2003-10-02 倍半萜烯合成酶及其使用方法
CN2010102391730A Expired - Fee Related CN101914558B (zh) 2002-10-04 2003-10-02 倍半萜烯合成酶及其使用方法

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CN2010102391730A Expired - Fee Related CN101914558B (zh) 2002-10-04 2003-10-02 倍半萜烯合成酶及其使用方法

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EP (3) EP2365070B1 (https=)
JP (1) JP4571862B2 (https=)
CN (3) CN1703507B (https=)
AU (1) AU2003278478A1 (https=)
BR (1) BR0314979A (https=)
IL (1) IL167832A (https=)
RU (1) RU2005113300A (https=)
WO (1) WO2004031376A2 (https=)

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JP5135215B2 (ja) 2005-07-01 2013-02-06 ユニバーシティー オブ ケンタッキー リサーチ ファンデーション モノテルペン及び／又はセスキテルペンを蓄積する形質転換植物
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CN101384719B (zh) * 2006-02-14 2012-10-03 弗门尼舍有限公司 用于生成萜的方法和用于该方法的mep转化后的微生物
US8110670B2 (en) 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
US20100242345A1 (en) 2006-05-19 2010-09-30 LS9, Inc Production of fatty acids & derivatives thereof
PL2252691T3 (pl) 2008-03-06 2013-08-30 Firmenich & Cie Sposób otrzymywania alfa-santalenu
WO2010019696A2 (en) 2008-08-12 2010-02-18 Allylix, Inc. Method for production of isoprenoids
ES2535722T3 (es) * 2008-12-05 2015-05-14 Keygene N.V. Farneseno sintasa
CN111808892A (zh) 2009-04-27 2020-10-23 基因组股份公司 脂肪酸酯的产生
EP2449107B1 (en) 2009-06-29 2015-04-08 The University Of Western Australia Terpene synthases from santalum
PT2493318T (pt) 2009-10-28 2016-12-23 Fundo De Defesa Da Citricultura - Fundecitrus Composições repelentes e abordagens genéticas para controlo de huanglongbing
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CN103282492A (zh) 2010-10-29 2013-09-04 奥利里克斯股份有限公司 修饰的瓦伦烯合酶多肽、编码核酸分子及其用途
EP2537926A1 (en) * 2011-06-21 2012-12-26 Isobionics B.V. Valencene synthase
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US9550815B2 (en) 2012-01-23 2017-01-24 University Of British Columbia ABC terpenoid transporters and methods of using the same
CN103243083B (zh) * 2012-02-06 2015-06-03 中国科学院上海生命科学研究院 一种新的倍半萜合成酶及其用途
US10000749B2 (en) 2013-03-14 2018-06-19 Evolva, Inc. Valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
ES2540791B1 (es) * 2013-12-13 2016-05-09 Consejo Superior De Investigaciones Científicas (Csic) Nuevas sesquiterpeno sintasas aisladas de la piel de naranja.
SG11201701278RA (en) * 2014-08-21 2017-03-30 Manus Biosynthesis Inc Methods for production of oxygenated terpenes
WO2017077125A1 (en) * 2015-11-05 2017-05-11 Firmenich S.A Drimenol synthases iii
CN105524908B (zh) * 2016-02-04 2018-12-28 中国农业科学院植物保护研究所 一种与(E)-β-石竹烯和(E)-a-律草烯合成相关的蛋白及其应用
CN110093329B (zh) * 2018-01-30 2023-07-04 深圳艾格鑫科技有限公司 萜类合酶及其应用
CN108977426B (zh) * 2018-06-29 2020-08-14 中国林业科学研究院热带林业研究所 一种油楠倍半萜合成酶及其编码基因和应用
CN109852600B (zh) * 2018-12-25 2021-12-31 天津大学 一种小萼苔倍半萜合成酶MTb及其基因序列
CN109666668B (zh) * 2019-01-24 2022-04-15 天津大学 一种小萼苔倍半萜合成酶MTa及其基因序列
CN109837266B (zh) * 2019-01-24 2021-12-31 天津大学 一种小萼苔倍半萜合成酶MTc及其基因序列
CN109929828A (zh) * 2019-01-30 2019-06-25 天津大学 一种苦皮藤倍半萜合成酶CaTPS1及其基因序列
CN111004763B (zh) * 2019-12-26 2022-06-03 中国科学院青岛生物能源与过程研究所 一种生产β-石竹烯的工程菌及其构建方法与应用
CN115404228B (zh) * 2021-05-28 2024-03-08 中国中医科学院中药研究所 山沉香倍半萜合酶蛋白tps1及其编码基因和应用
CN116004490A (zh) * 2022-07-12 2023-04-25 华东理工大学 一种生物合成右旋-双环吉玛烯的重组大肠杆菌、构建方法及应用
CN116555238B (zh) * 2023-06-09 2023-10-20 中国中医科学院中药研究所 SoSTPS1在作为倍半萜合酶中的应用
CN117126835B (zh) * 2023-08-11 2025-04-25 武汉合生科技有限公司 瓦伦烯合成酶及其应用
CN119899828B (zh) * 2025-01-17 2026-01-30 中国药科大学 利用SsDMS突变体高效生产新颖drimane型倍半萜化合物

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Publication number Publication date
EP3109319A1 (en) 2016-12-28
EP2365070B1 (en) 2016-09-14
EP2365070A1 (en) 2011-09-14
AU2003278478A1 (en) 2004-04-23
IL167832A (en) 2010-11-30
CN101914559B (zh) 2012-04-04
EP1554379A2 (en) 2005-07-20
WO2004031376A2 (en) 2004-04-15
CN1703507A (zh) 2005-11-30
CN101914559A (zh) 2010-12-15
BR0314979A (pt) 2005-08-02
CN101914558B (zh) 2013-05-29
RU2005113300A (ru) 2005-10-27
JP4571862B2 (ja) 2010-10-27
JP2006500942A (ja) 2006-01-12
EP1554379B1 (en) 2012-02-22
AU2003278478A8 (en) 2004-04-23
WO2004031376A3 (en) 2005-05-26
CN101914558A (zh) 2010-12-15

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