ATE545698T1 - Verfahren zur erzeugung dendritischer zellen unter einsatz einer gesunkenen temperatur - Google Patents

Verfahren zur erzeugung dendritischer zellen unter einsatz einer gesunkenen temperatur

Info

Publication number
ATE545698T1
ATE545698T1 AT06818153T AT06818153T ATE545698T1 AT E545698 T1 ATE545698 T1 AT E545698T1 AT 06818153 T AT06818153 T AT 06818153T AT 06818153 T AT06818153 T AT 06818153T AT E545698 T1 ATE545698 T1 AT E545698T1
Authority
AT
Austria
Prior art keywords
dendritic cells
lowered temperature
generating dendritic
generating
relates
Prior art date
Application number
AT06818153T
Other languages
English (en)
Inventor
Alexei Kirkin
Karine Djandjougazian
Jesper Zeuthen
Original Assignee
Dandrit Biotech As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dandrit Biotech As filed Critical Dandrit Biotech As
Application granted granted Critical
Publication of ATE545698T1 publication Critical patent/ATE545698T1/de

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0639Dendritic cells, e.g. Langherhans cells in the epidermis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/22Colony stimulating factors (G-CSF, GM-CSF)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/25Tumour necrosing factors [TNF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2523/00Culture process characterised by temperature

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT06818153T 2005-12-08 2006-12-07 Verfahren zur erzeugung dendritischer zellen unter einsatz einer gesunkenen temperatur ATE545698T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200501742 2005-12-08
PCT/DK2006/000694 WO2007065439A1 (en) 2005-12-08 2006-12-07 Method for generating dendritic cells employing decreased temperature

Publications (1)

Publication Number Publication Date
ATE545698T1 true ATE545698T1 (de) 2012-03-15

Family

ID=37745820

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06818153T ATE545698T1 (de) 2005-12-08 2006-12-07 Verfahren zur erzeugung dendritischer zellen unter einsatz einer gesunkenen temperatur

Country Status (18)

Country Link
US (1) US9771558B2 (de)
EP (1) EP1971680B1 (de)
JP (1) JP2009518017A (de)
CN (1) CN101321861B (de)
AT (1) ATE545698T1 (de)
AU (1) AU2006322451A1 (de)
BR (1) BRPI0619520A2 (de)
CA (1) CA2640836C (de)
CY (1) CY1113016T1 (de)
DK (1) DK1971680T3 (de)
EA (1) EA015266B1 (de)
ES (1) ES2382565T3 (de)
IL (1) IL191782A (de)
MY (1) MY145814A (de)
NO (1) NO20083023L (de)
NZ (1) NZ569343A (de)
PT (1) PT1971680E (de)
WO (1) WO2007065439A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009062502A1 (en) * 2007-11-13 2009-05-22 Dandrit Biotech A/S Method for generating tolerogenic dendritic cells employing decreased temperature
RU2486238C1 (ru) * 2011-12-29 2013-06-27 Государственное бюджетное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО СибГМУ Минздравсоцразвития России) СПОСОБ НАГРУЗКИ ДЕНДРИТНЫХ КЛЕТОК АНТИГЕНОМ ИНФЕКЦИОННОГО ПРОИСХОЖДЕНИЯ Opisthorchis felineus
RU2663468C1 (ru) * 2017-09-25 2018-08-06 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации Способ лечения местно-распространенного нерезектабельного рака поджелудочной железы
KR20220123033A (ko) * 2019-12-27 2022-09-05 제리아 신야쿠 고교 가부시키 가이샤 암 치료 방법 및 의약

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4306813B2 (ja) * 1995-09-19 2009-08-05 アスビオファーマ株式会社 動物細胞の新規培養方法
US5849589A (en) * 1996-03-11 1998-12-15 Duke University Culturing monocytes with IL-4, TNF-α and GM-CSF TO induce differentiation to dendric cells
US20050084966A1 (en) * 1999-04-20 2005-04-21 Edelson Richard L. Methods for inducing the differentiation of blood monocytes into functional dendritic cells
EP1259592A1 (de) * 2000-01-11 2002-11-27 Maxygen, Inc. Monozyten abgeleitete dendritische zellen untegruppen
CN1168740C (zh) * 2001-04-04 2004-09-29 上海美恩生物技术有限公司 细胞因子基因修饰的抗原提呈细胞/肿瘤细胞偶联物、其制法和用途
US20040009596A1 (en) * 2002-03-28 2004-01-15 Rao Kanury V. S. Extract from an Indian green mussel (perna viridis) for differentiation and maturation of dendric cells
JP4219789B2 (ja) 2002-10-30 2009-02-04 独立行政法人科学技術振興機構 骨髄由来の不死化樹状細胞株
JP2007525172A (ja) 2003-04-14 2007-09-06 ボード オブ リージェンツ ザ ユニバーティー オブ テキサス システム ポリクローナル抗体およびモノクローナル抗体のハイブリドーマ不要のエクスビボ産生法ならびに不死化細胞集団の作製法
US20050003533A1 (en) * 2003-05-08 2005-01-06 Pawel Kalinski Mature type-1 polarized dendritic cells with enhanced IL-12 production and methods of serum-free production and use
CN101155914B (zh) * 2005-04-08 2013-03-06 阿戈斯治疗公司 树状细胞组合物和方法

Also Published As

Publication number Publication date
NO20083023L (no) 2008-08-28
IL191782A0 (en) 2008-12-29
NZ569343A (en) 2011-11-25
IL191782A (en) 2012-05-31
EA015266B1 (ru) 2011-06-30
WO2007065439A1 (en) 2007-06-14
CN101321861B (zh) 2012-10-24
AU2006322451A1 (en) 2007-06-14
US20090196856A1 (en) 2009-08-06
ES2382565T3 (es) 2012-06-11
CA2640836C (en) 2018-05-15
BRPI0619520A2 (pt) 2011-10-04
EP1971680A1 (de) 2008-09-24
MY145814A (en) 2012-04-30
CN101321861A (zh) 2008-12-10
CA2640836A1 (en) 2007-06-14
DK1971680T3 (da) 2012-06-11
CY1113016T1 (el) 2016-04-13
EP1971680B1 (de) 2012-02-15
EA200801385A1 (ru) 2008-10-30
PT1971680E (pt) 2012-05-23
JP2009518017A (ja) 2009-05-07
US9771558B2 (en) 2017-09-26

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